These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Virtual screening and biological characterization of novel histone arginine methyltransferase PRMT1 inhibitors. Heinke R; Spannhoff A; Meier R; Trojer P; Bauer I; Jung M; Sippl W ChemMedChem; 2009 Jan; 4(1):69-77. PubMed ID: 19085993 [TBL] [Abstract][Full Text] [Related]
3. Histone methyltransferases in Aspergillus nidulans: evidence for a novel enzyme with a unique substrate specificity. Trojer P; Dangl M; Bauer I; Graessle S; Loidl P; Brosch G Biochemistry; 2004 Aug; 43(33):10834-43. PubMed ID: 15311944 [TBL] [Abstract][Full Text] [Related]
4. Small molecule inhibitors of histone arginine methyltransferases: homology modeling, molecular docking, binding mode analysis, and biological evaluations. Ragno R; Simeoni S; Castellano S; Vicidomini C; Mai A; Caroli A; Tramontano A; Bonaccini C; Trojer P; Bauer I; Brosch G; Sbardella G J Med Chem; 2007 Mar; 50(6):1241-53. PubMed ID: 17323938 [TBL] [Abstract][Full Text] [Related]
5. Small molecule inhibitors that discriminate between protein arginine N-methyltransferases PRMT1 and CARM1. Dowden J; Pike RA; Parry RV; Hong W; Muhsen UA; Ward SG Org Biomol Chem; 2011 Oct; 9(22):7814-21. PubMed ID: 21952734 [TBL] [Abstract][Full Text] [Related]
6. Transient Kinetics Define a Complete Kinetic Model for Protein Arginine Methyltransferase 1. Hu H; Luo C; Zheng YG J Biol Chem; 2016 Dec; 291(52):26722-26738. PubMed ID: 27834681 [TBL] [Abstract][Full Text] [Related]
7. Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor. Ferreira de Freitas R; Eram MS; Szewczyk MM; Steuber H; Smil D; Wu H; Li F; Senisterra G; Dong A; Brown PJ; Hitchcock M; Moosmayer D; Stegmann CM; Egner U; Arrowsmith C; Barsyte-Lovejoy D; Vedadi M; Schapira M J Med Chem; 2016 Feb; 59(3):1176-83. PubMed ID: 26824386 [TBL] [Abstract][Full Text] [Related]
8. In situ generation of a bisubstrate analogue for protein arginine methyltransferase 1. Osborne T; Roska RL; Rajski SR; Thompson PR J Am Chem Soc; 2008 Apr; 130(14):4574-5. PubMed ID: 18338885 [TBL] [Abstract][Full Text] [Related]
9. Discovery and mechanistic study of a class of protein arginine methylation inhibitors. Feng Y; Li M; Wang B; Zheng YG J Med Chem; 2010 Aug; 53(16):6028-39. PubMed ID: 20666457 [TBL] [Abstract][Full Text] [Related]
10. The Development of Tetrazole Derivatives as Protein Arginine Methyltransferase I (PRMT I) Inhibitors. Sun Y; Wang Z; Yang H; Zhu X; Wu H; Ma L; Xu F; Hong W; Wang H Int J Mol Sci; 2019 Aug; 20(15):. PubMed ID: 31390828 [TBL] [Abstract][Full Text] [Related]
11. Protein arginine methyltransferase 1: positively charged residues in substrate peptides distal to the site of methylation are important for substrate binding and catalysis. Osborne TC; Obianyo O; Zhang X; Cheng X; Thompson PR Biochemistry; 2007 Nov; 46(46):13370-81. PubMed ID: 17960915 [TBL] [Abstract][Full Text] [Related]
12. Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1. Bissinger EM; Heinke R; Spannhoff A; Eberlin A; Metzger E; Cura V; Hassenboehler P; Cavarelli J; Schüle R; Bedford MT; Sippl W; Jung M Bioorg Med Chem; 2011 Jun; 19(12):3717-31. PubMed ID: 21440447 [TBL] [Abstract][Full Text] [Related]
13. Arginine Methyltransferase 1 in the Nucleus Accumbens Regulates Behavioral Effects of Cocaine. Li Y; Zhu R; Wang W; Fu D; Hou J; Ji S; Chen B; Hu Z; Shao X; Yu X; Zhao Q; Zhang B; Du C; Bu Q; Hu C; Tang Y; Zhong L; Yang S; Zhao Y; Cen X J Neurosci; 2015 Sep; 35(37):12890-902. PubMed ID: 26377474 [TBL] [Abstract][Full Text] [Related]
14. Novel inhibitors for PRMT1 discovered by high-throughput screening using activity-based fluorescence polarization. Dillon MB; Bachovchin DA; Brown SJ; Finn MG; Rosen H; Cravatt BF; Mowen KA ACS Chem Biol; 2012 Jul; 7(7):1198-204. PubMed ID: 22506763 [TBL] [Abstract][Full Text] [Related]
15. Nη-substituted arginyl peptide inhibitors of protein arginine N-methyltransferases. Lakowski TM; 't Hart P; Ahern CA; Martin NI; Frankel A ACS Chem Biol; 2010 Nov; 5(11):1053-63. PubMed ID: 20701328 [TBL] [Abstract][Full Text] [Related]
16. Structural and biochemical evaluation of bisubstrate inhibitors of protein arginine N-methyltransferases PRMT1 and CARM1 (PRMT4). Gunnell EA; Al-Noori A; Muhsen U; Davies CC; Dowden J; Dreveny I Biochem J; 2020 Feb; 477(4):787-800. PubMed ID: 32011657 [TBL] [Abstract][Full Text] [Related]
17. A Pan-Inhibitor for Protein Arginine Methyltransferase Family Enzymes. Iyamu ID; Al-Hamashi AA; Huang R Biomolecules; 2021 Jun; 11(6):. PubMed ID: 34201091 [TBL] [Abstract][Full Text] [Related]
18. Histone H4-based peptoids are inhibitors of protein arginine methyltransferase 1 (PRMT1). Mann SA; DeMart MK; May B; Causey CP; Knuckley B Biochem J; 2020 Aug; 477(16):2971-2980. PubMed ID: 32716034 [TBL] [Abstract][Full Text] [Related]
19. Virtual screening and biological evaluation of novel small molecular inhibitors against protein arginine methyltransferase 1 (PRMT1). Xie Y; Zhou R; Lian F; Liu Y; Chen L; Shi Z; Zhang N; Zheng M; Shen B; Jiang H; Liang Z; Luo C Org Biomol Chem; 2014 Dec; 12(47):9665-73. PubMed ID: 25348815 [TBL] [Abstract][Full Text] [Related]
20. Investigating the binding preferences of small molecule inhibitors of human protein arginine methyltransferase 1 using molecular modelling. Hong W; Li J; Laughton CA; Yap LF; Paterson IC; Wang H J Mol Graph Model; 2014 Jun; 51():193-202. PubMed ID: 24937176 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]