285 related articles for article (PubMed ID: 17438137)
1. MLN8054, a small-molecule inhibitor of Aurora A, causes spindle pole and chromosome congression defects leading to aneuploidy.
Hoar K; Chakravarty A; Rabino C; Wysong D; Bowman D; Roy N; Ecsedy JA
Mol Cell Biol; 2007 Jun; 27(12):4513-25. PubMed ID: 17438137
[TBL] [Abstract][Full Text] [Related]
2. Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by Aurora A: a novel pharmacodynamic method for measuring Aurora A activity.
LeRoy PJ; Hunter JJ; Hoar KM; Burke KE; Shinde V; Ruan J; Bowman D; Galvin K; Ecsedy JA
Cancer Res; 2007 Jun; 67(11):5362-70. PubMed ID: 17545617
[TBL] [Abstract][Full Text] [Related]
3. MLN8054, an inhibitor of Aurora A kinase, induces senescence in human tumor cells both in vitro and in vivo.
Huck JJ; Zhang M; McDonald A; Bowman D; Hoar KM; Stringer B; Ecsedy J; Manfredi MG; Hyer ML
Mol Cancer Res; 2010 Mar; 8(3):373-84. PubMed ID: 20197380
[TBL] [Abstract][Full Text] [Related]
4. Phase I assessment of new mechanism-based pharmacodynamic biomarkers for MLN8054, a small-molecule inhibitor of Aurora A kinase.
Chakravarty A; Shinde V; Tabernero J; Cervantes A; Cohen RB; Dees EC; Burris H; Infante JR; Macarulla T; Elez E; Andreu J; Rodriguez-Braun E; Rosello S; von Mehren M; Meropol NJ; Langer CJ; ONeil B; Bowman D; Zhang M; Danaee H; Faron-Yowe L; Gray G; Liu H; Pappas J; Silverman L; Simpson C; Stringer B; Tirrell S; Veiby OP; Venkatakrishnan K; Galvin K; Manfredi M; Ecsedy JA
Cancer Res; 2011 Feb; 71(3):675-85. PubMed ID: 21148750
[TBL] [Abstract][Full Text] [Related]
5. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores.
Ditchfield C; Johnson VL; Tighe A; Ellston R; Haworth C; Johnson T; Mortlock A; Keen N; Taylor SS
J Cell Biol; 2003 Apr; 161(2):267-80. PubMed ID: 12719470
[TBL] [Abstract][Full Text] [Related]
6. Trivalent dimethylarsenic compound induces histone H3 phosphorylation and abnormal localization of Aurora B kinase in HepG2 cells.
Suzuki T; Miyazaki K; Kita K; Ochi T
Toxicol Appl Pharmacol; 2009 Dec; 241(3):275-82. PubMed ID: 19716834
[TBL] [Abstract][Full Text] [Related]
7. Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase.
Manfredi MG; Ecsedy JA; Meetze KA; Balani SK; Burenkova O; Chen W; Galvin KM; Hoar KM; Huck JJ; LeRoy PJ; Ray ET; Sells TB; Stringer B; Stroud SG; Vos TJ; Weatherhead GS; Wysong DR; Zhang M; Bolen JB; Claiborne CF
Proc Natl Acad Sci U S A; 2007 Mar; 104(10):4106-11. PubMed ID: 17360485
[TBL] [Abstract][Full Text] [Related]
8. ASAP is a novel substrate of the oncogenic mitotic kinase Aurora-A: phosphorylation on Ser625 is essential to spindle formation and mitosis.
Venoux M; Basbous J; Berthenet C; Prigent C; Fernandez A; Lamb NJ; Rouquier S
Hum Mol Genet; 2008 Jan; 17(2):215-24. PubMed ID: 17925329
[TBL] [Abstract][Full Text] [Related]
9. Pharmacologic abrogation of the mitotic spindle checkpoint by an indolocarbazole discovered by cellular screening efficiently kills cancer cells.
Stolz A; Vogel C; Schneider V; Ertych N; Kienitz A; Yu H; Bastians H
Cancer Res; 2009 May; 69(9):3874-83. PubMed ID: 19366805
[TBL] [Abstract][Full Text] [Related]
10. 2-methoxyestradiol induces spindle aberrations, chromosome congression failure, and nondisjunction in mouse oocytes.
Eichenlaub-Ritter U; Winterscheidt U; Vogt E; Shen Y; Tinneberg HR; Sorensen R
Biol Reprod; 2007 May; 76(5):784-93. PubMed ID: 17229934
[TBL] [Abstract][Full Text] [Related]
11. A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells.
Fielding AB; Lim S; Montgomery K; Dobreva I; Dedhar S
Oncogene; 2011 Feb; 30(5):521-34. PubMed ID: 20838383
[TBL] [Abstract][Full Text] [Related]
12. The inhibition of Aurora A abrogates the mitotic delay induced by microtubule perturbing agents.
Wysong DR; Chakravarty A; Hoar K; Ecsedy JA
Cell Cycle; 2009 Mar; 8(6):876-88. PubMed ID: 19221504
[TBL] [Abstract][Full Text] [Related]
13. Okadaic acid: chromosomal non-disjunction analysis in human lymphocytes and study of aneugenic pathway in CHO-K1 cells.
Hégarat LL; Orsière T; Botta A; Fessard V
Mutat Res; 2005 Oct; 578(1-2):53-63. PubMed ID: 15885711
[TBL] [Abstract][Full Text] [Related]
14. Septin1 is required for spindle assembly and chromosome congression in mouse oocytes.
Zhu J; Qi ST; Wang YP; Wang ZB; Ouyang YC; Hou Y; Schatten H; Sun QY
Dev Dyn; 2011 Oct; 240(10):2281-9. PubMed ID: 21932310
[TBL] [Abstract][Full Text] [Related]
15. Targeted disruption of Aurora A causes abnormal mitotic spindle assembly, chromosome misalignment and embryonic lethality.
Sasai K; Parant JM; Brandt ME; Carter J; Adams HP; Stass SA; Killary AM; Katayama H; Sen S
Oncogene; 2008 Jul; 27(29):4122-7. PubMed ID: 18345035
[TBL] [Abstract][Full Text] [Related]
16. Live imaging of spindle pole disorganization in docetaxel-treated multicolor cells.
Sakaushi S; Nishida K; Minamikawa H; Fukada T; Oka S; Sugimoto K
Biochem Biophys Res Commun; 2007 Jun; 357(3):655-60. PubMed ID: 17448447
[TBL] [Abstract][Full Text] [Related]
17. Aurora kinases in spindle assembly and chromosome segregation.
Ducat D; Zheng Y
Exp Cell Res; 2004 Nov; 301(1):60-7. PubMed ID: 15501446
[TBL] [Abstract][Full Text] [Related]
18. Trichlorfon predisposes to aneuploidy and interferes with spindle formation in in vitro maturing mouse oocytes.
Cukurcam S; Sun F; Betzendahl I; Adler ID; Eichenlaub-Ritter U
Mutat Res; 2004 Dec; 564(2):165-78. PubMed ID: 15507381
[TBL] [Abstract][Full Text] [Related]
19. Cytochalasin J affects chromosome congression and spindle microtubule organization in PtK1 cells.
Snyder JA; Cohen L
Cell Motil Cytoskeleton; 1995; 32(4):245-57. PubMed ID: 8608604
[TBL] [Abstract][Full Text] [Related]
20. Determinants for the efficiency of anticancer drugs targeting either Aurora-A or Aurora-B kinases in human colon carcinoma cells.
Kaestner P; Stolz A; Bastians H
Mol Cancer Ther; 2009 Jul; 8(7):2046-56. PubMed ID: 19584233
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
