These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

266 related articles for article (PubMed ID: 17442341)

  • 1. Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7.
    Miley MJ; Zielinska AK; Keenan JE; Bratton SM; Radominska-Pandya A; Redinbo MR
    J Mol Biol; 2007 Jun; 369(2):498-511. PubMed ID: 17442341
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families.
    Radominska-Pandya A; Bratton SM; Redinbo MR; Miley MJ
    Drug Metab Rev; 2010 Feb; 42(1):133-44. PubMed ID: 19821783
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Arginine-259 of UGT2B7 Confers UDP-Sugar Selectivity.
    Nair PC; Chau N; McKinnon RA; Miners JO
    Mol Pharmacol; 2020 Dec; 98(6):710-718. PubMed ID: 33008919
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis.
    Xiong Y; Patana AS; Miley MJ; Zielinska AK; Bratton SM; Miller GP; Goldman A; Finel M; Redinbo MR; Radominska-Pandya A
    Drug Metab Dispos; 2008 Mar; 36(3):517-22. PubMed ID: 18048489
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insights into the UDP-sugar selectivities of human UDP-glycosyltransferases (UGT): a molecular modeling perspective.
    Nair PC; Meech R; Mackenzie PI; McKinnon RA; Miners JO
    Drug Metab Rev; 2015 Aug; 47(3):335-45. PubMed ID: 26289097
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparative modelling of the human UDP-glucuronosyltransferases: insights into structure and mechanism.
    Locuson CW; Tracy TS
    Xenobiotica; 2007 Feb; 37(2):155-68. PubMed ID: 17484518
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Catalytic key amino acids and UDP-sugar donor specificity of a plant glucuronosyltransferase, UGT94B1: molecular modeling substantiated by site-specific mutagenesis and biochemical analyses.
    Osmani SA; Bak S; Imberty A; Olsen CE; Møller BL
    Plant Physiol; 2008 Nov; 148(3):1295-308. PubMed ID: 18829982
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Backbone assignment of the apo-form of the human C-terminal domain of UDP-glucuronosyltransferase 1A (UGT1A).
    Osborne MJ; Coutinho de Oliveira L; Volpon L; Borden KLB
    Biomol NMR Assign; 2018 Oct; 12(2):315-318. PubMed ID: 29934866
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human UDP-glucuronosyltransferase 2B7.
    Radominska-Pandya A; Little JM; Czernik PJ
    Curr Drug Metab; 2001 Sep; 2(3):283-98. PubMed ID: 11513331
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mapping the UDP-glucuronic acid binding site in UDP-glucuronosyltransferase-1A10 by homology-based modeling: confirmation with biochemical evidence.
    Banerjee R; Pennington MW; Garza A; Owens IS
    Biochemistry; 2008 Jul; 47(28):7385-92. PubMed ID: 18570380
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Amino terminal domains of human UDP-glucuronosyltransferases (UGT) 2B7 and 2B15 associated with substrate selectivity and autoactivation.
    Lewis BC; Mackenzie PI; Elliot DJ; Burchell B; Bhasker CR; Miners JO
    Biochem Pharmacol; 2007 May; 73(9):1463-73. PubMed ID: 17223084
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Relative enzymatic activity, protein stability, and tissue distribution of human steroid-metabolizing UGT2B subfamily members.
    Turgeon D; Carrier JS; Lévesque E; Hum DW; Bélanger A
    Endocrinology; 2001 Feb; 142(2):778-87. PubMed ID: 11159850
    [TBL] [Abstract][Full Text] [Related]  

  • 13.
    Osborne MJ; Rahardjo AK; Volpon L; Borden KLB
    Biomol NMR Assign; 2021 Oct; 15(2):323-328. PubMed ID: 33870481
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The human UDP-glucuronosyltransferase: identification of key residues within the nucleotide-sugar binding site.
    Patana AS; Kurkela M; Goldman A; Finel M
    Mol Pharmacol; 2007 Sep; 72(3):604-11. PubMed ID: 17578897
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Morphine glucuronidation and glucosidation represent complementary metabolic pathways that are both catalyzed by UDP-glucuronosyltransferase 2B7: kinetic, inhibition, and molecular modeling studies.
    Chau N; Elliot DJ; Lewis BC; Burns K; Johnston MR; Mackenzie PI; Miners JO
    J Pharmacol Exp Ther; 2014 Apr; 349(1):126-37. PubMed ID: 24459244
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inter-isoform Hetero-dimerization of Human UDP-Glucuronosyltransferases (UGTs) 1A1, 1A9, and 2B7 and Impacts on Glucuronidation Activity.
    Yuan LM; Gao ZZ; Sun HY; Qian SN; Xiao YS; Sun LL; Zeng S
    Sci Rep; 2016 Nov; 6():34450. PubMed ID: 27857056
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Understanding substrate selectivity of human UDP-glucuronosyltransferases through QSAR modeling and analysis of homologous enzymes.
    Dong D; Ako R; Hu M; Wu B
    Xenobiotica; 2012 Aug; 42(8):808-20. PubMed ID: 22385482
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The importance of local chemical structure for chemical metabolism by human uridine 5'-diphosphate-glucuronosyltransferase.
    Sorich MJ; McKinnon RA; Miners JO; Smith PA
    J Chem Inf Model; 2006; 46(6):2692-7. PubMed ID: 17125209
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Homodimerization of UDP-glucuronosyltransferase 2B7 (UGT2B7) and identification of a putative dimerization domain by protein homology modeling.
    Lewis BC; Mackenzie PI; Miners JO
    Biochem Pharmacol; 2011 Dec; 82(12):2016-23. PubMed ID: 21930117
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7.
    Mackenzie P; Little JM; Radominska-Pandya A
    Biochem Pharmacol; 2003 Feb; 65(3):417-21. PubMed ID: 12527334
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.