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BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

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  • 1. On call. I am 57 years old, and as far as I know, my health is excellent. At my last check-up, my doctor said that I was in perfect health except that my cholesterol was too high. Please tell me what you think of these results: cholesterol 243, LDL cholesterol 162, HDL cholesterol 68, and triglycerides 86. Everything else was "normal".
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  • 2. On call. I'm a 63-year-old man with arthritis but no other conditions. My only medicines were Naprosyn and vitamins until my last annual checkup, when my cholesterol was high. My doctor gave me Zocor, which helped. But I developed muscle aches, so he switched me to Zetia. I feel fine again, but I'd like to know what you think.
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  • 3. Ask the Doctor: I am a woman, age 48, in generally good health, although I've gained about 10 pounds over the past two years. My LDL cholesterol us 142 mg/dL and my HDL cholesterol is 58 mg/dL. I looked at the news reports on the new cholesterol guidelines and was extremely unhappy to see that my LDL is "borderline high". My doctor says I don't need drug therapy. What do you think?
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  • 4. I'm 56 years old and have total cholesterol of 217 milligrams per deciliter, LDL of 131 mg/dl, HDL of 67 mg/dl, and a total-to-HDL ratio of 3.24. My doctor says that ratio is good for a woman my age, so why does she want me to lower my LDL?
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  • 9. Ask the doctor. My cholesterol profile is pretty good, except that my HDL level is only 32 mg/dL, and I know the normal range is 40 or more. My LDL cholesterol is 110 mg/dL and my triglycerides are in the normal range. I don't have a history of heart disease and I've never had any symptoms (or diagnosis) of heart disease. Should I be taking a drug to raise my HDL?
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  • 11. Ask the doctors. I am a 62-year-old female with no chronic health problems, but I am about 10 pounds overweight. My new doctor wants to put me on a statin immediately. My total cholesterol is 187: my LDL is 129, my HDL is 47, and my triglycerides are 55. He is concerned because my father died of a heart attack from coronary artery disease. The doctor wants my HDL to be above 60 and my LDL to be below 100. Could this result be achieved by weight loss, dietary changes, and exercise alone? If not, which statin would you recommend?
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  • 12. Ask the doctor. Can I lower my LDL level by raising my triglycerides?
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  • 13. My doctor has me taking Lopid (gemfibrozil) twice a day. My cholesterol level is only 187, but my HDL cholesterol is low at 25. My LDL cholesterol is"normal" at 98 and my triglycerides are 318. These pills give me stomach cramps and they are expensive. Do I need to take them?
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  • 14. Ask the doctor. I am a 59-year-old man. The results of my latest blood test showed that my LDL cholesterol was 67, which was flagged as low. (I do not take any cholesterol-lowering drugs.) Should I be worried, or do anything to raise my LDL?
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  • 15. Ask the doctor. Just two years ago, my total cholesterol was 175 mg/dL, and my LDL cholesterol was 128 mg/dL. This week my doctor told me that my cholesterol was 240 and my LDL was 170. I haven't gained any weight or changed my diet--what's going on?
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  • 16. I've read that I should lower my triglycerides as well as my cholesterol. What's the difference, and what should I do to lower them?
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