These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

311 related articles for article (PubMed ID: 17446301)

  • 1. Wash-resistantly bound xanomeline inhibits acetylcholine release by persistent activation of presynaptic M(2) and M(4) muscarinic receptors in rat brain.
    Machová E; Jakubík J; El-Fakahany EE; Dolezal V
    J Pharmacol Exp Ther; 2007 Jul; 322(1):316-23. PubMed ID: 17446301
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differences in kinetics of xanomeline binding and selectivity of activation of G proteins at M(1) and M(2) muscarinic acetylcholine receptors.
    Jakubík J; El-Fakahany EE; Dolezal V
    Mol Pharmacol; 2006 Aug; 70(2):656-66. PubMed ID: 16675658
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Persistent binding and functional antagonism by xanomeline at the muscarinic M5 receptor.
    Grant MK; El-Fakahany EE
    J Pharmacol Exp Ther; 2005 Oct; 315(1):313-9. PubMed ID: 16002459
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Long-term changes in the muscarinic M1 receptor induced by instantaneous formation of wash-resistant xanomeline-receptor complex.
    De Lorme KC; Grant MK; Noetzel MJ; Polson SB; El-Fakahany EE
    J Pharmacol Exp Ther; 2007 Dec; 323(3):868-76. PubMed ID: 17855477
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional effects of the muscarinic receptor agonist, xanomeline, at 5-HT1 and 5-HT2 receptors.
    Watson J; Brough S; Coldwell MC; Gager T; Ho M; Hunter AJ; Jerman J; Middlemiss DN; Riley GJ; Brown AM
    Br J Pharmacol; 1998 Dec; 125(7):1413-20. PubMed ID: 9884068
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacological analysis of the novel mode of interaction between xanomeline and the M1 muscarinic acetylcholine receptor.
    Christopoulos A; Parsons AM; El-Fakahany EE
    J Pharmacol Exp Ther; 1999 Jun; 289(3):1220-8. PubMed ID: 10336509
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of receptor protein and membrane lipids in xanomeline wash-resistant binding to muscarinic M1 receptors.
    Jakubík J; Tucek S; El-Fakahany EE
    J Pharmacol Exp Ther; 2004 Jan; 308(1):105-10. PubMed ID: 14569060
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Low-affinity M(2) receptor binding state mediates mouse atrial bradycardia: comparative effects of carbamylcholine and the M(1) receptor agonists sabcomeline and xanomeline.
    Stengel PW; Cohen ML
    J Pharmacol Exp Ther; 2001 Mar; 296(3):818-24. PubMed ID: 11181912
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Long-term wash-resistant effects of brief interaction of xanomeline at the M1 muscarinic receptor.
    De Lorme KC; Sikorski KL; Grant MK; El-Fakahany EE
    Neurosci Lett; 2006 Dec; 410(1):11-4. PubMed ID: 17052840
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and evaluation of xanomeline analogs--probing the wash-resistant phenomenon at the M1 muscarinic acetylcholine receptor.
    Kane BE; Grant MK; El-Fakahany EE; Ferguson DM
    Bioorg Med Chem; 2008 Feb; 16(3):1376-92. PubMed ID: 17977730
    [TBL] [Abstract][Full Text] [Related]  

  • 11. On the unique binding and activating properties of xanomeline at the M1 muscarinic acetylcholine receptor.
    Christopoulos A; Pierce TL; Sorman JL; El-Fakahany EE
    Mol Pharmacol; 1998 Jun; 53(6):1120-30. PubMed ID: 9614217
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Allosteric modulation by persistent binding of xanomeline of the interaction of competitive ligands with the M1 muscarinic acetylcholine receptor.
    Jakubík J; Tucek S; El-Fakahany EE
    J Pharmacol Exp Ther; 2002 Jun; 301(3):1033-41. PubMed ID: 12023535
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Long-term activation upon brief exposure to xanomleline is unique to M1 and M4 subtypes of muscarinic acetylcholine receptors.
    Šantrůčková E; Doležal V; El-Fakahany EE; Jakubík J
    PLoS One; 2014; 9(2):e88910. PubMed ID: 24558448
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Attenuation of amphetamine-induced activity by the non-selective muscarinic receptor agonist, xanomeline, is absent in muscarinic M4 receptor knockout mice and attenuated in muscarinic M1 receptor knockout mice.
    Woolley ML; Carter HJ; Gartlon JE; Watson JM; Dawson LA
    Eur J Pharmacol; 2009 Jan; 603(1-3):147-9. PubMed ID: 19111716
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Xanomeline: a novel muscarinic receptor agonist with functional selectivity for M1 receptors.
    Shannon HE; Bymaster FP; Calligaro DO; Greenwood B; Mitch CH; Sawyer BD; Ward JS; Wong DT; Olesen PH; Sheardown MJ; Swedberg MD; Suzdak PD; Sauerberg P
    J Pharmacol Exp Ther; 1994 Apr; 269(1):271-81. PubMed ID: 7909557
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Agonist-mediated regulation of presynaptic receptor function during development of rat septal neurons in culture.
    Ehret A; Birthelmer A; Rutz S; Riegert C; Rothmaier AK; Jackisch R
    J Neurochem; 2007 Aug; 102(4):1071-82. PubMed ID: 17472710
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-function studies of allosteric agonism at M2 muscarinic acetylcholine receptors.
    May LT; Avlani VA; Langmead CJ; Herdon HJ; Wood MD; Sexton PM; Christopoulos A
    Mol Pharmacol; 2007 Aug; 72(2):463-76. PubMed ID: 17525129
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Classical and atypical agonists activate M1 muscarinic acetylcholine receptors through common mechanisms.
    Randáková A; Dolejší E; Rudajev V; Zimčík P; Doležal V; El-Fakahany EE; Jakubík J
    Pharmacol Res; 2015 Jul; 97():27-39. PubMed ID: 25882246
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of glutamate release from primary afferents and interneurons in the spinal cord by muscarinic receptor subtypes.
    Zhang HM; Chen SR; Pan HL
    J Neurophysiol; 2007 Jan; 97(1):102-9. PubMed ID: 17050831
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacological evaluation of the long-term effects of xanomeline on the M(1) muscarinic acetylcholine receptor.
    Grant MK; Noetzel MJ; De Lorme KC; Jakubík J; Doležal V; El-Fakahany EE
    PLoS One; 2010 Dec; 5(12):e15722. PubMed ID: 21203415
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.