205 related articles for article (PubMed ID: 17448659)
1. Design and synthesis of novel hydantoin-containing melanin-concentrating hormone receptor antagonists.
Balavoine F; Malabre P; Alleaume T; Rey A; Cherfils V; Jeanneton O; Seigneurin-Venin S; Revah F
Bioorg Med Chem Lett; 2007 Jul; 17(13):3754-9. PubMed ID: 17448659
[TBL] [Abstract][Full Text] [Related]
2. Substituted chromones and quinolones as potent melanin-concentrating hormone receptor 1 antagonists.
Dyck B; Zhao L; Tamiya J; Pontillo J; Hudson S; Ching B; Heise CE; Wen J; Norton C; Madan A; Schwarz D; Wade W; Goodfellow VS
Bioorg Med Chem Lett; 2006 Aug; 16(16):4237-42. PubMed ID: 16762549
[TBL] [Abstract][Full Text] [Related]
3. Thienopyrimidinone bis-aminopyrrolidine ureas as potent melanin-concentrating hormone receptor-1 (MCH-R1) antagonists.
Zhang M; Tamiya J; Nguyen L; Rowbottom MW; Dyck B; Vickers TD; Grey J; Schwarz DA; Heise CE; Haelewyn J; Mistry MS; Goodfellow VS
Bioorg Med Chem Lett; 2007 May; 17(9):2535-9. PubMed ID: 17329101
[TBL] [Abstract][Full Text] [Related]
4. Bicyclo[3.1.0]hexyl urea melanin concentrating hormone (MCH) receptor-1 antagonists: impacting hERG liability via aryl modifications.
McBriar MD; Guzik H; Shapiro S; Xu R; Paruchova J; Clader JW; O'neill K; Hawes B; Sorota S; Margulis M; Tucker K; Weston DJ; Cox K
Bioorg Med Chem Lett; 2006 Aug; 16(16):4262-5. PubMed ID: 16753297
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of novel bicyclo[4.1.0]heptane and bicyclo[3.1.0]hexane derivatives as melanin-concentrating hormone receptor R1 antagonists.
Su J; Tang H; McKittrick BA; Gu H; Guo T; Qian G; Burnett DA; Clader JW; Greenlee WJ; Hawes BE; O'neill K; Spar B; Weig B; Kowalski T; Sorota S
Bioorg Med Chem Lett; 2007 Sep; 17(17):4845-50. PubMed ID: 17604169
[TBL] [Abstract][Full Text] [Related]
6. Solid-phase synthesis and structure-activity relationships of novel biarylethers as melanin-concentrating hormone receptor-1 antagonists.
Ma V; Bannon AW; Baumgartner J; Hale C; Hsieh F; Hulme C; Rorrer K; Salon J; van Staden C; Tempest P
Bioorg Med Chem Lett; 2006 Oct; 16(19):5066-72. PubMed ID: 16887348
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and structure-activity relationships of spirohydantoin-derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1).
Rowbottom MW; Vickers TD; Tamiya J; Zhang M; Dyck B; Grey J; Schwarz D; Heise CE; Hedrick M; Wen J; Tang H; Wang H; Fisher A; Aparicio A; Saunders J; Goodfellow VS
Bioorg Med Chem Lett; 2007 Apr; 17(8):2171-8. PubMed ID: 17350839
[TBL] [Abstract][Full Text] [Related]
8. Design and optimization of quinazoline derivatives as melanin concentrating hormone receptor 1 (MCHR1) antagonists: part 2.
Sasmal S; Balasubrahmanyam D; Kanna Reddy HR; Balaji G; Srinivas G; Cheera S; Abbineni C; Sasmal PK; Khanna I; Sebastian VJ; Jadhav VP; Singh MP; Talwar R; Suresh J; Shashikumar D; Harinder Reddy K; Sihorkar V; Frimurer TM; Rist Ø; Elster L; Högberg T
Bioorg Med Chem Lett; 2012 May; 22(9):3163-7. PubMed ID: 22497763
[TBL] [Abstract][Full Text] [Related]
9. Structure-activity relationships of a novel series of melanin-concentrating hormone (MCH) receptor antagonists.
Arienzo R; Clark DE; Cramp S; Daly S; Dyke HJ; Lockey P; Norman D; Roach AG; Stuttle K; Tomlinson M; Wong M; Wren SP
Bioorg Med Chem Lett; 2004 Aug; 14(15):4099-102. PubMed ID: 15225734
[TBL] [Abstract][Full Text] [Related]
10. Design and synthesis of orally efficacious benzimidazoles as melanin-concentrating hormone receptor 1 antagonists.
Wu WL; Burnett DA; Caplen MA; Domalski MS; Bennett C; Greenlee WJ; Hawes BE; O'Neill K; Weig B; Weston D; Spar B; Kowalski T
Bioorg Med Chem Lett; 2006 Jul; 16(14):3674-8. PubMed ID: 16690315
[TBL] [Abstract][Full Text] [Related]
11. Novel approach for chemotype hopping based on annotated databases of chemically feasible fragments and a prospective case study: new melanin concentrating hormone antagonists.
Oyarzabal J; Howe T; Alcazar J; Andrés JI; Alvarez RM; Dautzenberg F; Iturrino L; Martínez S; Van der Linden I
J Med Chem; 2009 Apr; 52(7):2076-89. PubMed ID: 19290642
[TBL] [Abstract][Full Text] [Related]
12. The use of three-dimensional shape and electrostatic similarity searching in the identification of a melanin-concentrating hormone receptor 1 antagonist.
Muchmore SW; Souers AJ; Akritopoulou-Zanze I
Chem Biol Drug Des; 2006 Feb; 67(2):174-6. PubMed ID: 16492165
[TBL] [Abstract][Full Text] [Related]
13. Discovery and characterization of a potent and selective antagonist of melanin-concentrating hormone receptor 2.
Chen X; Mihalic J; Fan P; Liang L; Lindstrom M; Wong S; Ye Q; Fu Y; Jaen J; Chen JL; Dai K; Li L
Bioorg Med Chem Lett; 2012 Jan; 22(1):363-6. PubMed ID: 22123324
[TBL] [Abstract][Full Text] [Related]
14. Tandem optimization of target activity and elimination of mutagenic potential in a potent series of N-aryl bicyclic hydantoin-based selective androgen receptor modulators.
Hamann LG; Manfredi MC; Sun C; Krystek SR; Huang Y; Bi Y; Augeri DJ; Wang T; Zou Y; Betebenner DA; Fura A; Seethala R; Golla R; Kuhns JE; Lupisella JA; Darienzo CJ; Custer LL; Price JL; Johnson JM; Biller SA; Zahler R; Ostrowski J
Bioorg Med Chem Lett; 2007 Apr; 17(7):1860-4. PubMed ID: 17292608
[TBL] [Abstract][Full Text] [Related]
15. 4-Acylamino-and 4-ureidobenzamides as melanin-concentrating hormone (MCH) receptor 1 antagonists.
Receveur JM; Bjurling E; Ulven T; Little PB; Nørregaard PK; Högberg T
Bioorg Med Chem Lett; 2004 Oct; 14(20):5075-80. PubMed ID: 15380202
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and structure-activity relationships of retro bis-aminopyrrolidine urea (rAPU) derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Part 1.
Rowbottom MW; Vickers TD; Dyck B; Grey J; Tamiya J; Zhang M; Kiankarimi M; Wu D; Dwight W; Wade WS; Schwarz D; Heise CE; Madan A; Fisher A; Petroski R; Goodfellow VS
Bioorg Med Chem Lett; 2006 Sep; 16(17):4450-7. PubMed ID: 16814542
[TBL] [Abstract][Full Text] [Related]
17. Discovery of novel chemotypes to a G-protein-coupled receptor through ligand-steered homology modeling and structure-based virtual screening.
Cavasotto CN; Orry AJ; Murgolo NJ; Czarniecki MF; Kocsi SA; Hawes BE; O'Neill KA; Hine H; Burton MS; Voigt JH; Abagyan RA; Bayne ML; Monsma FJ
J Med Chem; 2008 Feb; 51(3):581-8. PubMed ID: 18198821
[TBL] [Abstract][Full Text] [Related]
18. Discovery of novel spiro-piperidine derivatives as highly potent and selective melanin-concentrating hormone 1 receptor antagonists.
Suzuki T; Moriya M; Sakamoto T; Suga T; Kishino H; Takahashi H; Ishikawa M; Nagai K; Imai Y; Sekino E; Ito M; Iwaasa H; Ishihara A; Tokita S; Kanatani A; Sato N; Fukami T
Bioorg Med Chem Lett; 2009 Jun; 19(11):3072-7. PubMed ID: 19403308
[TBL] [Abstract][Full Text] [Related]
19. Novel H3 receptor antagonists with improved pharmacokinetic profiles.
Santora VJ; Covel JA; Hayashi R; Hofilena BJ; Ibarra JB; Pulley MD; Weinhouse MI; Semple G; Ren A; Pereira G; Edwards JE; Suarez M; Frazer J; Thomsen W; Hauser E; Lorea J; Grottick AJ
Bioorg Med Chem Lett; 2008 Jul; 18(14):4133-6. PubMed ID: 18554904
[TBL] [Abstract][Full Text] [Related]
20. 2-Arylpyrimidines: novel CRF-1 receptor antagonists.
Yoon T; De Lombaert S; Brodbeck R; Gulianello M; Krause JE; Hutchison A; Horvath RF; Ge P; Kehne J; Hoffman D; Chandrasekhar J; Doller D; Hodgetts KJ
Bioorg Med Chem Lett; 2008 Aug; 18(16):4486-90. PubMed ID: 18672365
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]