BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 17453413)

  • 1. Cation coupling properties of human concentrative nucleoside transporters hCNT1, hCNT2 and hCNT3.
    Smith KM; Slugoski MD; Cass CE; Baldwin SA; Karpinski E; Young JD
    Mol Membr Biol; 2007; 24(1):53-64. PubMed ID: 17453413
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The broadly selective human Na+/nucleoside cotransporter (hCNT3) exhibits novel cation-coupled nucleoside transport characteristics.
    Smith KM; Slugoski MD; Loewen SK; Ng AM; Yao SY; Chen XZ; Karpinski E; Cass CE; Baldwin SA; Young JD
    J Biol Chem; 2005 Jul; 280(27):25436-49. PubMed ID: 15870078
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Uridine binding and transportability determinants of human concentrative nucleoside transporters.
    Zhang J; Smith KM; Tackaberry T; Visser F; Robins MJ; Nielsen LP; Nowak I; Karpinski E; Baldwin SA; Young JD; Cass CE
    Mol Pharmacol; 2005 Sep; 68(3):830-9. PubMed ID: 15955867
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Recent molecular advances in studies of the concentrative Na+-dependent nucleoside transporter (CNT) family: identification and characterization of novel human and mouse proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib).
    Ritzel MW; Ng AM; Yao SY; Graham K; Loewen SK; Smith KM; Hyde RJ; Karpinski E; Cass CE; Baldwin SA; Young JD
    Mol Membr Biol; 2001; 18(1):65-72. PubMed ID: 11396613
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An ancient prevertebrate Na+-nucleoside cotransporter (hfCNT) from the Pacific hagfish (Eptatretus stouti).
    Yao SY; Ng AM; Loewen SK; Cass CE; Baldwin SA; Young JD
    Am J Physiol Cell Physiol; 2002 Jul; 283(1):C155-68. PubMed ID: 12055084
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interaction of fused-pyrimidine nucleoside analogs with human concentrative nucleoside transporters: High-affinity inhibitors of human concentrative nucleoside transporter 1.
    Damaraju VL; Smith KM; Mowles D; Nowak I; Karpinski E; Young JD; Robins MJ; Cass CE
    Biochem Pharmacol; 2011 Jan; 81(1):82-90. PubMed ID: 20854794
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of human nucleoside transporters in the cellular uptake of two inhibitors of IMP dehydrogenase, tiazofurin and benzamide riboside.
    Damaraju VL; Visser F; Zhang J; Mowles D; Ng AM; Young JD; Jayaram HN; Cass CE
    Mol Pharmacol; 2005 Jan; 67(1):273-9. PubMed ID: 15486050
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transport of physiological nucleosides and anti-viral and anti-neoplastic nucleoside drugs by recombinant Escherichia coli nucleoside-H(+) cotransporter (NupC) produced in Xenopus laevis oocytes.
    Loewen SK; Yao SY; Slugoski MD; Mohabir NN; Turner RJ; Mackey JR; Weiner JH; Gallagher MP; Henderson PJ; Baldwin SA; Cass CE; Young JD
    Mol Membr Biol; 2004; 21(1):1-10. PubMed ID: 14668133
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib).
    Ritzel MW; Ng AM; Yao SY; Graham K; Loewen SK; Smith KM; Ritzel RG; Mowles DA; Carpenter P; Chen XZ; Karpinski E; Hyde RJ; Baldwin SA; Cass CE; Young JD
    J Biol Chem; 2001 Jan; 276(4):2914-27. PubMed ID: 11032837
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interactions of nucleoside analogs, caffeine, and nicotine with human concentrative nucleoside transporters 1 and 2 stably produced in a transport-defective human cell line.
    Lang TT; Young JD; Cass CE
    Mol Pharmacol; 2004 Apr; 65(4):925-33. PubMed ID: 15044622
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Specific mutations in transmembrane helix 8 of human concentrative Na+/nucleoside cotransporter hCNT1 affect permeant selectivity and cation coupling.
    Slugoski MD; Loewen SK; Ng AM; Smith KM; Yao SY; Karpinski E; Cass CE; Baldwin SA; Young JD
    Biochemistry; 2007 Feb; 46(6):1684-93. PubMed ID: 17279631
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A proton-mediated conformational shift identifies a mobile pore-lining cysteine residue (Cys-561) in human concentrative nucleoside transporter 3.
    Slugoski MD; Ng AM; Yao SY; Smith KM; Lin CC; Zhang J; Karpinski E; Cass CE; Baldwin SA; Young JD
    J Biol Chem; 2008 Mar; 283(13):8496-507. PubMed ID: 18199742
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Substituted cysteine accessibility method (SCAM) analysis of the transport domain of human concentrative nucleoside transporter 3 (hCNT3) and other family members reveals features of structural and functional importance.
    Mulinta R; Yao SYM; Ng AML; Cass CE; Young JD
    J Biol Chem; 2017 Jun; 292(23):9505-9522. PubMed ID: 28385889
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A conformationally mobile cysteine residue (Cys-561) modulates Na+ and H+ activation of human CNT3.
    Slugoski MD; Smith KM; Mulinta R; Ng AM; Yao SY; Morrison EL; Lee QO; Zhang J; Karpinski E; Cass CE; Baldwin SA; Young JD
    J Biol Chem; 2008 Sep; 283(36):24922-34. PubMed ID: 18621735
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular requirements of the human nucleoside transporters hCNT1, hCNT2, and hENT1.
    Chang C; Swaan PW; Ngo LY; Lum PY; Patil SD; Unadkat JD
    Mol Pharmacol; 2004 Mar; 65(3):558-70. PubMed ID: 14978234
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Localization of broadly selective equilibrative and concentrative nucleoside transporters, hENT1 and hCNT3, in human kidney.
    Damaraju VL; Elwi AN; Hunter C; Carpenter P; Santos C; Barron GM; Sun X; Baldwin SA; Young JD; Mackey JR; Sawyer MB; Cass CE
    Am J Physiol Renal Physiol; 2007 Jul; 293(1):F200-11. PubMed ID: 17409283
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Conserved glutamate residues Glu-343 and Glu-519 provide mechanistic insights into cation/nucleoside cotransport by human concentrative nucleoside transporter hCNT3.
    Slugoski MD; Smith KM; Ng AML; Yao SYM; Karpinski E; Cass CE; Baldwin SA; Young JD
    J Biol Chem; 2009 Jun; 284(25):17266-17280. PubMed ID: 19380587
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HPLC reveals novel features of nucleoside and nucleobase homeostasis, nucleoside metabolism and nucleoside transport.
    Altaweraqi RA; Yao SYM; Smith KM; Cass CE; Young JD
    Biochim Biophys Acta Biomembr; 2020 Jul; 1862(7):183247. PubMed ID: 32126230
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2.
    Loewen SK; Ng AM; Yao SY; Cass CE; Baldwin SA; Young JD
    J Biol Chem; 1999 Aug; 274(35):24475-84. PubMed ID: 10455109
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ribavirin uptake by cultured human choriocarcinoma (BeWo) cells and Xenopus laevis oocytes expressing recombinant plasma membrane human nucleoside transporters.
    Yamamoto T; Kuniki K; Takekuma Y; Hirano T; Iseki K; Sugawara M
    Eur J Pharmacol; 2007 Feb; 557(1):1-8. PubMed ID: 17140564
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.