170 related articles for article (PubMed ID: 17455929)
21. Novel 1-hydroxyazole bioisosteres of glutamic acid. Synthesis, protolytic properties, and pharmacology.
Stensbøl TB; Uhlmann P; Morel S; Eriksen BL; Felding J; Kromann H; Hermit MB; Greenwood JR; Braüner-Osborne H; Madsen U; Junager F; Krogsgaard-Larsen P; Begtrup M; Vedsø P
J Med Chem; 2002 Jan; 45(1):19-31. PubMed ID: 11754576
[TBL] [Abstract][Full Text] [Related]
22. Structural determinants of AMPA agonist activity in analogues of 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid: synthesis and pharmacology.
Bang-Andersen B; Ahmadian H; Lenz SM; Stensbøl TB; Madsen U; Bøgesø KP; Krogsgaard-Larsen P
J Med Chem; 2000 Dec; 43(25):4910-8. PubMed ID: 11124000
[TBL] [Abstract][Full Text] [Related]
23. 3-hydroxypyridazine 1-oxides as carboxylate bioisosteres: a new series of subtype-selective AMPA receptor agonists.
Greenwood JR; Mewett KN; Allan RD; Martín BO; Pickering DS
Neuropharmacology; 2006 Jul; 51(1):52-9. PubMed ID: 16631211
[TBL] [Abstract][Full Text] [Related]
24. A new phenylalanine derivative acts as an antagonist at the AMPA receptor GluA2 and introduces partial domain closure: synthesis, resolution, pharmacology, and crystal structure.
Szymańska E; Frydenvang K; Contreras-Sanz A; Pickering DS; Frola E; Serafimoska Z; Nielsen B; Kastrup JS; Johansen TN
J Med Chem; 2011 Oct; 54(20):7289-98. PubMed ID: 21923187
[TBL] [Abstract][Full Text] [Related]
25. Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4.
Kasper C; Frydenvang K; Naur P; Gajhede M; Pickering DS; Kastrup JS
FEBS Lett; 2008 Dec; 582(29):4089-94. PubMed ID: 19022251
[TBL] [Abstract][Full Text] [Related]
26. Mechanism of activation and selectivity in a ligand-gated ion channel: structural and functional studies of GluR2 and quisqualate.
Jin R; Horning M; Mayer ML; Gouaux E
Biochemistry; 2002 Dec; 41(52):15635-43. PubMed ID: 12501192
[TBL] [Abstract][Full Text] [Related]
27. Selective agonist binding of (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) and 2S-(2alpha,3beta,4beta)-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid (kainate) receptors: a molecular modeling study.
Pentikäinen OT; Settimo L; Keinänen K; Johnson MS
Biochem Pharmacol; 2003 Dec; 66(12):2413-25. PubMed ID: 14637199
[TBL] [Abstract][Full Text] [Related]
28. Structural determinants for AMPA agonist activity of aryl or heteroaryl substituted AMPA analogues. Synthesis and pharmacology.
Sørensen US; Falch E; Stensbøl TB; Jaroszewski JW; Madsen U; Krogsgaard-Larsen P
Arch Pharm (Weinheim); 2001 Feb; 334(2):62-8. PubMed ID: 11268776
[TBL] [Abstract][Full Text] [Related]
29. Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor.
Armstrong N; Jasti J; Beich-Frandsen M; Gouaux E
Cell; 2006 Oct; 127(1):85-97. PubMed ID: 17018279
[TBL] [Abstract][Full Text] [Related]
30. Molecular pharmacology of the AMPA agonist, (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazolyl)propionic acid [(S)-APPA] and the AMPA antagonist, (R)-APPA.
Ebert B; Madsen U; Lund TM; Lenz SM; Krogsgaard-Larsen P
Neurochem Int; 1994 Jun; 24(6):507-15. PubMed ID: 7526921
[TBL] [Abstract][Full Text] [Related]
31. Stereochemistry of glutamate receptor agonist efficacy: engineering a dual-specificity AMPA/kainate receptor.
Madden DR; Cheng Q; Thiran S; Rajan S; Rigo F; Keinänen K; Reinelt S; Zimmermann H; Jayaraman V
Biochemistry; 2004 Dec; 43(50):15838-44. PubMed ID: 15595838
[TBL] [Abstract][Full Text] [Related]
32. A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study.
Holm MM; Naur P; Vestergaard B; Geballe MT; Gajhede M; Kastrup JS; Traynelis SF; Egebjerg J
J Biol Chem; 2005 Oct; 280(42):35469-76. PubMed ID: 16103115
[TBL] [Abstract][Full Text] [Related]
33. Resolution, absolute stereochemistry, and enantiopharmacology of the GluR1-4 and GluR5 antagonist 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid.
Møller EH; Egebjerg J; Brehm L; Stensbøl TB; Johansen TN; Madsen U; Krogsgaard-Larsen P
Chirality; 1999; 11(10):752-9. PubMed ID: 10561704
[TBL] [Abstract][Full Text] [Related]
34. Different characteristics of AMPA receptor agonists acting at AMPA receptors expressed in Xenopus oocytes.
Wahl P; Madsen U; Banke T; Krogsgaard-Larsen P; Schousboe A
Eur J Pharmacol; 1996 Jul; 308(2):211-8. PubMed ID: 8840134
[TBL] [Abstract][Full Text] [Related]
35. GluR2 ligand-binding core complexes: importance of the isoxazolol moiety and 5-substituent for the binding mode of AMPA-type agonists.
Kasper C; Lunn ML; Liljefors T; Gouaux E; Egebjerg J; Kastrup JS
FEBS Lett; 2002 Nov; 531(2):173-8. PubMed ID: 12417307
[TBL] [Abstract][Full Text] [Related]
36. Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core.
Hogner A; Kastrup JS; Jin R; Liljefors T; Mayer ML; Egebjerg J; Larsen IK; Gouaux E
J Mol Biol; 2002 Sep; 322(1):93-109. PubMed ID: 12215417
[TBL] [Abstract][Full Text] [Related]
37. The selective activation of the glutamate receptor GluR5 by ATPA is controlled by serine 741.
Nielsen MM; Liljefors T; Krogsgaard-Larsen P; Egebjerg J
Mol Pharmacol; 2003 Jan; 63(1):19-25. PubMed ID: 12488532
[TBL] [Abstract][Full Text] [Related]
38. Divergent effects of the purinoceptor antagonists suramin and pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate) (PPNDS) on alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors.
Suzuki E; Kessler M; Montgomery K; Arai AC
Mol Pharmacol; 2004 Dec; 66(6):1738-47. PubMed ID: 15448189
[TBL] [Abstract][Full Text] [Related]
39. Tweaking Subtype Selectivity and Agonist Efficacy at (S)-2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) Receptors in a Small Series of BnTetAMPA Analogues.
Wang SY; Larsen Y; Navarrete CV; Jensen AA; Nielsen B; Al-Musaed A; Frydenvang K; Kastrup JS; Pickering DS; Clausen RP
J Med Chem; 2016 Mar; 59(5):2244-54. PubMed ID: 26862980
[TBL] [Abstract][Full Text] [Related]
40. Use of [3H]fluorowillardiine to study properties of AMPA receptor allosteric modulators.
Kessler M; Arai AC
Brain Res; 2006 Mar; 1076(1):25-41. PubMed ID: 16256076
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
