These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

300 related articles for article (PubMed ID: 17456595)

  • 1. Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties.
    Wang J; Kodali S; Lee SH; Galgoci A; Painter R; Dorso K; Racine F; Motyl M; Hernandez L; Tinney E; Colletti SL; Herath K; Cummings R; Salazar O; González I; Basilio A; Vicente F; Genilloud O; Pelaez F; Jayasuriya H; Young K; Cully DF; Singh SB
    Proc Natl Acad Sci U S A; 2007 May; 104(18):7612-6. PubMed ID: 17456595
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Isolation and structure of platencin: a FabH and FabF dual inhibitor with potent broad-spectrum antibiotic activity.
    Jayasuriya H; Herath KB; Zhang C; Zink DL; Basilio A; Genilloud O; Diez MT; Vicente F; Gonzalez I; Salazar O; Pelaez F; Cummings R; Ha S; Wang J; Singh SB
    Angew Chem Int Ed Engl; 2007; 46(25):4684-8. PubMed ID: 17487925
    [No Abstract]   [Full Text] [Related]  

  • 3. Total syntheses of (+/-)-platencin and (-)-platencin.
    Nicolaou KC; Tria GS; Edmonds DJ; Kar M
    J Am Chem Soc; 2009 Nov; 131(43):15909-17. PubMed ID: 19824676
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Review of Platensimycin and Platencin: Inhibitors of β-Ketoacyl-acyl Carrier Protein (ACP) Synthase III (FabH).
    Shang R; Liang J; Yi Y; Liu Y; Wang J
    Molecules; 2015 Sep; 20(9):16127-41. PubMed ID: 26404223
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Platensimycin is a selective FabF inhibitor with potent antibiotic properties.
    Wang J; Soisson SM; Young K; Shoop W; Kodali S; Galgoci A; Painter R; Parthasarathy G; Tang YS; Cummings R; Ha S; Dorso K; Motyl M; Jayasuriya H; Ondeyka J; Herath K; Zhang C; Hernandez L; Allocco J; Basilio A; Tormo JR; Genilloud O; Vicente F; Pelaez F; Colwell L; Lee SH; Michael B; Felcetto T; Gill C; Silver LL; Hermes JD; Bartizal K; Barrett J; Schmatz D; Becker JW; Cully D; Singh SB
    Nature; 2006 May; 441(7091):358-61. PubMed ID: 16710421
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural Characterisation of the Beta-Ketoacyl-Acyl Carrier Protein Synthases, FabF and FabH, of Yersinia pestis.
    Nanson JD; Himiari Z; Swarbrick CM; Forwood JK
    Sci Rep; 2015 Oct; 5():14797. PubMed ID: 26469877
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural characterization of β-ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites.
    Patterson EI; Nanson JD; Abendroth J; Bryan C; Sankaran B; Myler PJ; Forwood JK
    Proteins; 2020 Jan; 88(1):47-56. PubMed ID: 31237717
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Asymmetric Synthesis and Biological Evaluation of Platensilin, Platensimycin, Platencin, and Their Analogs via a Bioinspired Skeletal Reconstruction Approach.
    Gao ZX; Wang H; Su AH; Li QY; Liang Z; Zhang YQ; Liu XY; Zhu MZ; Zhang HX; Hou YT; Li X; Sun LR; Li J; Xu ZJ; Lou HX
    J Am Chem Soc; 2024 Jul; 146(28):18967-18978. PubMed ID: 38973592
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Platensimycin and platencin: promising antibiotics for future application in human medicine.
    Martens E; Demain AL
    J Antibiot (Tokyo); 2011 Nov; 64(11):705-10. PubMed ID: 21915133
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Platensimycin and platencin congeners from Streptomyces platensis.
    Zhang C; Ondeyka J; Herath K; Jayasuriya H; Guan Z; Zink DL; Dietrich L; Burgess B; Ha SN; Wang J; Singh SB
    J Nat Prod; 2011 Mar; 74(3):329-40. PubMed ID: 21214253
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Platensimycin: a promising antimicrobial targeting fatty acid synthesis.
    Manallack DT; Crosby IT; Khakham Y; Capuano B
    Curr Med Chem; 2008; 15(7):705-10. PubMed ID: 18336284
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of FabH/FabF inhibitors from natural products.
    Young K; Jayasuriya H; Ondeyka JG; Herath K; Zhang C; Kodali S; Galgoci A; Painter R; Brown-Driver V; Yamamoto R; Silver LL; Zheng Y; Ventura JI; Sigmund J; Ha S; Basilio A; Vicente F; Tormo JR; Pelaez F; Youngman P; Cully D; Barrett JF; Schmatz D; Singh SB; Wang J
    Antimicrob Agents Chemother; 2006 Feb; 50(2):519-26. PubMed ID: 16436705
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains.
    Peterson RM; Huang T; Rudolf JD; Smanski MJ; Shen B
    Chem Biol; 2014 Mar; 21(3):389-397. PubMed ID: 24560608
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and antibacterial properties of (-)-nor-platencin.
    Barykina OV; Rossi KL; Rybak MJ; Snider BB
    Org Lett; 2009 Nov; 11(22):5334-7. PubMed ID: 19845392
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Purification, characterization, and identification of novel inhibitors of the beta-ketoacyl-acyl carrier protein synthase III (FabH) from Staphylococcus aureus.
    He X; Reynolds KA
    Antimicrob Agents Chemother; 2002 May; 46(5):1310-8. PubMed ID: 11959561
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.
    Singh SB; Ondeyka JG; Herath KB; Zhang C; Jayasuriya H; Zink DL; Parthasarathy G; Becker JW; Wang J; Soisson SM
    Bioorg Med Chem Lett; 2009 Aug; 19(16):4756-9. PubMed ID: 19581087
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Advances in the research of β-ketoacyl-ACP synthase III (FabH) inhibitors.
    Zhang HJ; Li ZL; Zhu HL
    Curr Med Chem; 2012; 19(8):1225-37. PubMed ID: 22257054
    [TBL] [Abstract][Full Text] [Related]  

  • 18. FabH mutations confer resistance to FabF-directed antibiotics in Staphylococcus aureus.
    Parsons JB; Yao J; Frank MW; Rock CO
    Antimicrob Agents Chemother; 2015 Feb; 59(2):849-58. PubMed ID: 25403676
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Engineering of Streptomyces platensis MA7339 for overproduction of platencin and congeners.
    Yu Z; Smanski MJ; Peterson RM; Marchillo K; Andes D; Rajski SR; Shen B
    Org Lett; 2010 Apr; 12(8):1744-7. PubMed ID: 20232845
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure and semisynthesis of platensimide A, produced by Streptomyces platensis.
    Herath KB; Zhang C; Jayasuriya H; Ondeyka JG; Zink DL; Burgess B; Wang J; Singh SB
    Org Lett; 2008 May; 10(9):1699-702. PubMed ID: 18393511
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.