286 related articles for article (PubMed ID: 17456723)
1. Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells.
Zhang F; Thornhill SI; Howe SJ; Ulaganathan M; Schambach A; Sinclair J; Kinnon C; Gaspar HB; Antoniou M; Thrasher AJ
Blood; 2007 Sep; 110(5):1448-57. PubMed ID: 17456723
[TBL] [Abstract][Full Text] [Related]
2. Physiological regulation of transgene expression by a lentiviral vector containing the A2UCOE linked to a myeloid promoter.
Brendel C; Müller-Kuller U; Schultze-Strasser S; Stein S; Chen-Wichmann L; Krattenmacher A; Kunkel H; Dillmann A; Antoniou MN; Grez M
Gene Ther; 2012 Oct; 19(10):1018-29. PubMed ID: 22071971
[TBL] [Abstract][Full Text] [Related]
3. Long-term reproducible expression in human fetal liver hematopoietic stem cells with a UCOE-based lentiviral vector.
Dighe N; Khoury M; Mattar C; Chong M; Choolani M; Chen J; Antoniou MN; Chan JK
PLoS One; 2014; 9(8):e104805. PubMed ID: 25118036
[TBL] [Abstract][Full Text] [Related]
4. A ubiquitous chromatin opening element (UCOE) confers resistance to DNA methylation-mediated silencing of lentiviral vectors.
Zhang F; Frost AR; Blundell MP; Bales O; Antoniou MN; Thrasher AJ
Mol Ther; 2010 Sep; 18(9):1640-9. PubMed ID: 20588258
[TBL] [Abstract][Full Text] [Related]
5. Efficiency of different fragment lengths of the ubiquitous chromatin opening element HNRPA2B1-CBX3 in driving human CD18 gene expression within self-inactivating lentiviral vectors for gene therapy applications.
Gopinath C; Chodisetty S; Ghosh A; Nelson EJR
Gene; 2019 Aug; 710():265-272. PubMed ID: 31200085
[TBL] [Abstract][Full Text] [Related]
6. Lentiviral MGMT(P140K)-mediated in vivo selection employing a ubiquitous chromatin opening element (A2UCOE) linked to a cellular promoter.
Phaltane R; Lachmann N; Brennig S; Ackermann M; Modlich U; Moritz T
Biomaterials; 2014 Aug; 35(25):7204-13. PubMed ID: 24875758
[TBL] [Abstract][Full Text] [Related]
7. Interplay of Promoter Usage and Intragenic CpG Content: Impact on GFP Reporter Gene Expression.
Krinner S; Heitzer A; Asbach B; Wagner R
Hum Gene Ther; 2015 Dec; 26(12):826-40. PubMed ID: 26414116
[TBL] [Abstract][Full Text] [Related]
8. Safer, silencing-resistant lentiviral vectors: optimization of the ubiquitous chromatin-opening element through elimination of aberrant splicing.
Knight S; Zhang F; Mueller-Kuller U; Bokhoven M; Gupta A; Broughton T; Sha S; Antoniou MN; Brendel C; Grez M; Thrasher AJ; Collins M; Takeuchi Y
J Virol; 2012 Sep; 86(17):9088-95. PubMed ID: 22696657
[TBL] [Abstract][Full Text] [Related]
9. A ubiquitous chromatin opening element prevents transgene silencing in pluripotent stem cells and their differentiated progeny.
Pfaff N; Lachmann N; Ackermann M; Kohlscheen S; Brendel C; Maetzig T; Niemann H; Antoniou MN; Grez M; Schambach A; Cantz T; Moritz T
Stem Cells; 2013 Mar; 31(3):488-99. PubMed ID: 23307570
[TBL] [Abstract][Full Text] [Related]
10. Sustained and regulated gene expression by Tet-inducible "all-in-one" retroviral vectors containing the HNRPA2B1-CBX3 UCOE
Cullmann K; Blokland KEC; Sebe A; Schenk F; Ivics Z; Heinz N; Modlich U
Biomaterials; 2019 Feb; 192():486-499. PubMed ID: 30508767
[TBL] [Abstract][Full Text] [Related]
11. Correction of murine Rag2 severe combined immunodeficiency by lentiviral gene therapy using a codon-optimized RAG2 therapeutic transgene.
van Til NP; de Boer H; Mashamba N; Wabik A; Huston M; Visser TP; Fontana E; Poliani PL; Cassani B; Zhang F; Thrasher AJ; Villa A; Wagemaker G
Mol Ther; 2012 Oct; 20(10):1968-80. PubMed ID: 22692499
[TBL] [Abstract][Full Text] [Related]
12. Correlation of DNA methylation with histone modifications across the HNRPA2B1-CBX3 ubiquitously-acting chromatin open element (UCOE).
Lindahl Allen M; Antoniou M
Epigenetics; 2007; 2(4):227-36. PubMed ID: 18032920
[TBL] [Abstract][Full Text] [Related]
13. Ubiquitous Chromatin-opening Elements (UCOEs): Applications in biomanufacturing and gene therapy.
Neville JJ; Orlando J; Mann K; McCloskey B; Antoniou MN
Biotechnol Adv; 2017 Sep; 35(5):557-564. PubMed ID: 28528197
[TBL] [Abstract][Full Text] [Related]
14. High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency [correction of imunodeficiency] virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter.
Demaison C; Parsley K; Brouns G; Scherr M; Battmer K; Kinnon C; Grez M; Thrasher AJ
Hum Gene Ther; 2002 May; 13(7):803-13. PubMed ID: 11975847
[TBL] [Abstract][Full Text] [Related]
15. Lentiviral Vectors Mediate Long-Term and High Efficiency Transgene Expression in HEK 293T cells.
Mao Y; Yan R; Li A; Zhang Y; Li J; Du H; Chen B; Wei W; Zhang Y; Sumners C; Zheng H; Li H
Int J Med Sci; 2015; 12(5):407-15. PubMed ID: 26005375
[TBL] [Abstract][Full Text] [Related]
16. Detailed comparison of retroviral vectors and promoter configurations for stable and high transgene expression in human induced pluripotent stem cells.
Hoffmann D; Schott JW; Geis FK; Lange L; Müller FJ; Lenz D; Zychlinski D; Steinemann D; Morgan M; Moritz T; Schambach A
Gene Ther; 2017 May; 24(5):298-307. PubMed ID: 28346436
[TBL] [Abstract][Full Text] [Related]
17. A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells.
Müller-Kuller U; Ackermann M; Kolodziej S; Brendel C; Fritsch J; Lachmann N; Kunkel H; Lausen J; Schambach A; Moritz T; Grez M
Nucleic Acids Res; 2015 Feb; 43(3):1577-92. PubMed ID: 25605798
[TBL] [Abstract][Full Text] [Related]
18. Chromatin function modifying elements in an industrial antibody production platform--comparison of UCOE, MAR, STAR and cHS4 elements.
Saunders F; Sweeney B; Antoniou MN; Stephens P; Cain K
PLoS One; 2015; 10(4):e0120096. PubMed ID: 25849659
[TBL] [Abstract][Full Text] [Related]
19. Transgenes encompassing dual-promoter CpG islands from the human TBP and HNRPA2B1 loci are resistant to heterochromatin-mediated silencing.
Antoniou M; Harland L; Mustoe T; Williams S; Holdstock J; Yague E; Mulcahy T; Griffiths M; Edwards S; Ioannou PA; Mountain A; Crombie R
Genomics; 2003 Sep; 82(3):269-79. PubMed ID: 12906852
[TBL] [Abstract][Full Text] [Related]
20. Promoter and lineage independent anti-silencing activity of the A2 ubiquitous chromatin opening element for optimized human pluripotent stem cell-based gene therapy.
Ackermann M; Lachmann N; Hartung S; Eggenschwiler R; Pfaff N; Happle C; Mucci A; Göhring G; Niemann H; Hansen G; Schambach A; Cantz T; Zweigerdt R; Moritz T
Biomaterials; 2014 Feb; 35(5):1531-42. PubMed ID: 24290698
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
