102 related articles for article (PubMed ID: 17459932)
21. Inhibition of hepatitis C virus replication by Monascus pigment derivatives that interfere with viral RNA polymerase activity and the mevalonate biosynthesis pathway.
Sun JM; Kim SJ; Kim GW; Rhee JK; Kim ND; Jung H; Jeun J; Lee SH; Han SH; Shin CS; Oh JW
J Antimicrob Chemother; 2012 Jan; 67(1):49-58. PubMed ID: 22076990
[TBL] [Abstract][Full Text] [Related]
22. Chiral gold(I) vs chiral silver complexes as catalysts for the enantioselective synthesis of the second generation GSK-hepatitis C virus inhibitor.
Martín-Rodríguez M; Nájera C; Sansano JM; de Cózar A; Cossío FP
Beilstein J Org Chem; 2011; 7():988-96. PubMed ID: 21915198
[TBL] [Abstract][Full Text] [Related]
23. Discovery of naturally occurring aurones that are potent allosteric inhibitors of hepatitis C virus RNA-dependent RNA polymerase.
Haudecoeur R; Ahmed-Belkacem A; Yi W; Fortuné A; Brillet R; Belle C; Nicolle E; Pallier C; Pawlotsky JM; Boumendjel A
J Med Chem; 2011 Aug; 54(15):5395-402. PubMed ID: 21699179
[TBL] [Abstract][Full Text] [Related]
24. Antiviral activity and mode of action of TMC647078, a novel nucleoside inhibitor of the hepatitis C virus NS5B polymerase.
Berke JM; Vijgen L; Lachau-Durand S; Powdrill MH; Rawe S; Sjuvarsson E; Eriksson S; Götte M; Fransen E; Dehertogh P; Van den Eynde C; Leclercq L; Jonckers TH; Raboisson P; Nilsson M; Samuelsson B; Rosenquist Å; Fanning GC; Lin TI
Antimicrob Agents Chemother; 2011 Aug; 55(8):3812-20. PubMed ID: 21576430
[TBL] [Abstract][Full Text] [Related]
25. De novo polymerase activity and oligomerization of hepatitis C virus RNA-dependent RNA-polymerases from genotypes 1 to 5.
Clemente-Casares P; López-Jiménez AJ; Bellón-Echeverría I; Encinar JA; Martínez-Alfaro E; Pérez-Flores R; Mas A
PLoS One; 2011 Apr; 6(4):e18515. PubMed ID: 21490973
[TBL] [Abstract][Full Text] [Related]
26. Comparison of the Mechanisms of Drug Resistance among HIV, Hepatitis B, and Hepatitis C.
Margeridon-Thermet S; Shafer RW
Viruses; 2010 Dec; 2(12):2696-739. PubMed ID: 21243082
[TBL] [Abstract][Full Text] [Related]
27. Inhibition of dengue virus polymerase by blocking of the RNA tunnel.
Niyomrattanakit P; Chen YL; Dong H; Yin Z; Qing M; Glickman JF; Lin K; Mueller D; Voshol H; Lim JY; Nilar S; Keller TH; Shi PY
J Virol; 2010 Jun; 84(11):5678-86. PubMed ID: 20237086
[TBL] [Abstract][Full Text] [Related]
28. Mechanism and specificity of a symmetrical benzimidazolephenylcarboxamide helicase inhibitor.
Belon CA; High YD; Lin TI; Pauwels F; Frick DN
Biochemistry; 2010 Mar; 49(9):1822-32. PubMed ID: 20108979
[TBL] [Abstract][Full Text] [Related]
29. 1a/1b subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus.
Nyanguile O; Devogelaere B; Vijgen L; Van den Broeck W; Pauwels F; Cummings MD; De Bondt HL; Vos AM; Berke JM; Lenz O; Vandercruyssen G; Vermeiren K; Mostmans W; Dehertogh P; Delouvroy F; Vendeville S; VanDyck K; Dockx K; Cleiren E; Raboisson P; Simmen KA; Fanning GC
J Virol; 2010 Mar; 84(6):2923-34. PubMed ID: 20071590
[TBL] [Abstract][Full Text] [Related]
30. Slow binding inhibition and mechanism of resistance of non-nucleoside polymerase inhibitors of hepatitis C virus.
Hang JQ; Yang Y; Harris SF; Leveque V; Whittington HJ; Rajyaguru S; Ao-Ieong G; McCown MF; Wong A; Giannetti AM; Le Pogam S; Talamás F; Cammack N; Nájera I; Klumpp K
J Biol Chem; 2009 Jun; 284(23):15517-29. PubMed ID: 19246450
[TBL] [Abstract][Full Text] [Related]
31. 1,5-benzodiazepines, a novel class of hepatitis C virus polymerase nonnucleoside inhibitors.
Nyanguile O; Pauwels F; Van den Broeck W; Boutton CW; Quirynen L; Ivens T; van der Helm L; Vandercruyssen G; Mostmans W; Delouvroy F; Dehertogh P; Cummings MD; Bonfanti JF; Simmen KA; Raboisson P
Antimicrob Agents Chemother; 2008 Dec; 52(12):4420-31. PubMed ID: 18852280
[TBL] [Abstract][Full Text] [Related]
32. Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors.
Paeshuyse J; Vliegen I; Coelmont L; Leyssen P; Tabarrini O; Herdewijn P; Mittendorfer H; Easmon J; Cecchetti V; Bartenschlager R; Puerstinger G; Neyts J
Antimicrob Agents Chemother; 2008 Sep; 52(9):3433-7. PubMed ID: 18625766
[TBL] [Abstract][Full Text] [Related]
33. Functional characterization of fingers subdomain-specific monoclonal antibodies inhibiting the hepatitis C virus RNA-dependent RNA polymerase.
Nikonov A; Juronen E; Ustav M
J Biol Chem; 2008 Aug; 283(35):24089-102. PubMed ID: 18574240
[TBL] [Abstract][Full Text] [Related]
34. Effects of mutagenic and chain-terminating nucleotide analogs on enzymes isolated from hepatitis C virus strains of various genotypes.
Heck JA; Lam AM; Narayanan N; Frick DN
Antimicrob Agents Chemother; 2008 Jun; 52(6):1901-11. PubMed ID: 18391043
[TBL] [Abstract][Full Text] [Related]
35. Binding-site identification and genotypic profiling of hepatitis C virus polymerase inhibitors.
Pauwels F; Mostmans W; Quirynen LM; van der Helm L; Boutton CW; Rueff AS; Cleiren E; Raboisson P; Surleraux D; Nyanguile O; Simmen KA
J Virol; 2007 Jul; 81(13):6909-19. PubMed ID: 17459932
[TBL] [Abstract][Full Text] [Related]
36. RNA-dependent RNA polymerases from different hepatitis C virus genotypes reveal distinct biochemical properties and drug susceptibilities.
May MM; Lorengel H; Kreuter J; Zimmermann H; Ruebsamen-Schaeff H; Urban A
Biochim Biophys Acta; 2011 Oct; 1814(10):1325-32. PubMed ID: 21621653
[TBL] [Abstract][Full Text] [Related]
37. Optimization of novel acyl pyrrolidine inhibitors of hepatitis C virus RNA-dependent RNA polymerase leading to a development candidate.
Slater MJ; Amphlett EM; Andrews DM; Bravi G; Burton G; Cheasty AG; Corfield JA; Ellis MR; Fenwick RH; Fernandes S; Guidetti R; Haigh D; Hartley CD; Howes PD; Jackson DL; Jarvest RL; Lovegrove VL; Medhurst KJ; Parry NR; Price H; Shah P; Singh OM; Stocker R; Thommes P; Wilkinson C; Wonacott A
J Med Chem; 2007 Mar; 50(5):897-900. PubMed ID: 17269759
[TBL] [Abstract][Full Text] [Related]
38. Identification of a novel resistance mutation for benzimidazole inhibitors of the HCV RNA-dependent RNA polymerase.
Delang L; Froeyen M; Herdewijn P; Neyts J
Antiviral Res; 2012 Jan; 93(1):30-8. PubMed ID: 22033247
[TBL] [Abstract][Full Text] [Related]
39. Identification of small molecule inhibitors of the hepatitis C virus RNA-dependent RNA polymerase from a pyrrolidine combinatorial mixture.
Burton G; Ku TW; Carr TJ; Kiesow T; Sarisky RT; Lin-Goerke J; Baker A; Earnshaw DL; Hofmann GA; Keenan RM; Dhanak D
Bioorg Med Chem Lett; 2005 Mar; 15(6):1553-6. PubMed ID: 15745795
[TBL] [Abstract][Full Text] [Related]
40. Identification of novel HCV RNA-dependent RNA polymerase inhibitors using pharmacophore-guided virtual screening.
Kim J; Kim KS; Kim DE; Chong Y
Chem Biol Drug Des; 2008 Dec; 72(6):585-91. PubMed ID: 19090925
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
