BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

555 related articles for article (PubMed ID: 17463090)

  • 1. Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity.
    Siddiquee K; Zhang S; Guida WC; Blaskovich MA; Greedy B; Lawrence HR; Yip ML; Jove R; McLaughlin MM; Lawrence NJ; Sebti SM; Turkson J
    Proc Natl Acad Sci U S A; 2007 May; 104(18):7391-6. PubMed ID: 17463090
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel small-molecule disrupts Stat3 SH2 domain-phosphotyrosine interactions and Stat3-dependent tumor processes.
    Zhang X; Yue P; Fletcher S; Zhao W; Gunning PT; Turkson J
    Biochem Pharmacol; 2010 May; 79(10):1398-409. PubMed ID: 20067773
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An oxazole-based small-molecule Stat3 inhibitor modulates Stat3 stability and processing and induces antitumor cell effects.
    Siddiquee KA; Gunning PT; Glenn M; Katt WP; Zhang S; Schrock C; Sebti SM; Jove R; Hamilton AD; Turkson J
    ACS Chem Biol; 2007 Dec; 2(12):787-98. PubMed ID: 18154266
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A cell-permeable Stat3 SH2 domain mimetic inhibits Stat3 activation and induces antitumor cell effects in vitro.
    Zhao W; Jaganathan S; Turkson J
    J Biol Chem; 2010 Nov; 285(46):35855-65. PubMed ID: 20807764
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells.
    Lin L; Hutzen B; Li PK; Ball S; Zuo M; DeAngelis S; Foust E; Sobo M; Friedman L; Bhasin D; Cen L; Li C; Lin J
    Neoplasia; 2010 Jan; 12(1):39-50. PubMed ID: 20072652
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent.
    Ball DP; Lewis AM; Williams D; Resetca D; Wilson DJ; Gunning PT
    Oncotarget; 2016 Apr; 7(15):20669-79. PubMed ID: 26942696
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Micellar nano-carriers for the delivery of STAT3 dimerization inhibitors to melanoma.
    Soleimani AH; Garg SM; Paiva IM; Vakili MR; Alshareef A; Huang YH; Molavi O; Lai R; Lavasanifar A
    Drug Deliv Transl Res; 2017 Aug; 7(4):571-581. PubMed ID: 28290050
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel inhibitor of STAT3 homodimerization selectively suppresses STAT3 activity and malignant transformation.
    Zhang X; Sun Y; Pireddu R; Yang H; Urlam MK; Lawrence HR; Guida WC; Lawrence NJ; Sebti SM
    Cancer Res; 2013 Mar; 73(6):1922-33. PubMed ID: 23322008
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy.
    Pang M; Ma L; Gong R; Tolbert E; Mao H; Ponnusamy M; Chin YE; Yan H; Dworkin LD; Zhuang S
    Kidney Int; 2010 Aug; 78(3):257-68. PubMed ID: 20520592
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Impact of STAT3 inhibition on survival of osteosarcoma cell lines.
    Wang X; Goldstein D; Crowe PJ; Yang JL
    Anticancer Res; 2014 Nov; 34(11):6537-45. PubMed ID: 25368256
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The STAT3 inhibitor S3I-201 suppresses fibrogenesis and angiogenesis in liver fibrosis.
    Wang Z; Li J; Xiao W; Long J; Zhang H
    Lab Invest; 2018 Dec; 98(12):1600-1613. PubMed ID: 30206312
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ginkgetin inhibits the growth of DU-145 prostate cancer cells through inhibition of signal transducer and activator of transcription 3 activity.
    Jeon YJ; Jung SN; Yun J; Lee CW; Choi J; Lee YJ; Han DC; Kwon BM
    Cancer Sci; 2015 Apr; 106(4):413-20. PubMed ID: 25611086
    [TBL] [Abstract][Full Text] [Related]  

  • 13. STAT3 upregulation in pituitary somatotroph adenomas induces growth hormone hypersecretion.
    Zhou C; Jiao Y; Wang R; Ren SG; Wawrowsky K; Melmed S
    J Clin Invest; 2015 Apr; 125(4):1692-702. PubMed ID: 25774503
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of STAT3 activity delays obesity-induced thyroid carcinogenesis in a mouse model.
    Park JW; Han CR; Zhao L; Willingham MC; Cheng SY
    Endocr Relat Cancer; 2016 Jan; 23(1):53-63. PubMed ID: 26552408
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Strategies and Approaches of Targeting STAT3 for Cancer Treatment.
    Furtek SL; Backos DS; Matheson CJ; Reigan P
    ACS Chem Biol; 2016 Feb; 11(2):308-18. PubMed ID: 26730496
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation.
    Duan Z; Bradner JE; Greenberg E; Levine R; Foster R; Mahoney J; Seiden MV
    Clin Cancer Res; 2006 Nov; 12(22):6844-52. PubMed ID: 17121906
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo.
    Huang W; Dong Z; Chen Y; Wang F; Wang CJ; Peng H; He Y; Hangoc G; Pollok K; Sandusky G; Fu XY; Broxmeyer HE; Zhang ZY; Liu JY; Zhang JT
    Oncogene; 2016 Feb; 35(6):783-92. PubMed ID: 26073084
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening.
    Leung KH; Liu LJ; Lin S; Lu L; Zhong HJ; Susanti D; Rao W; Wang M; Che WI; Chan DS; Leung CH; Chan PW; Ma DL
    Methods; 2015 Jan; 71():38-43. PubMed ID: 25160651
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Involvement of fish signal transducer and activator of transcription 3 (STAT3) in SGIV replication and virus induced paraptosis.
    Huang X; Huang Y; Yang Y; Wei S; Qin Q
    Fish Shellfish Immunol; 2014 Dec; 41(2):308-16. PubMed ID: 25230133
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A specific STAT3-binding peptide exerts antiproliferative effects and antitumor activity by inhibiting STAT3 phosphorylation and signaling.
    Kim D; Lee IH; Kim S; Choi M; Kim H; Ahn S; Saw PE; Jeon H; Lee Y; Jon S
    Cancer Res; 2014 Apr; 74(8):2144-51. PubMed ID: 24576829
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.