BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

335 related articles for article (PubMed ID: 17464964)

  • 1. Synthesis and anti-HIV-1 activity of new MKC-442 analogues with an alkynyl-substituted 6-benzyl group.
    Aly YL; Pedersen EB; La Colla P; Loddo R
    Arch Pharm (Weinheim); 2007 May; 340(5):225-35. PubMed ID: 17464964
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of novel MKC-442 analogues with potent activities against HIV-1.
    El-Brollosy NR; Pedersen EB; Nielsen C
    Arch Pharm (Weinheim); 2003 Jul; 336(4-5):236-41. PubMed ID: 12916058
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of novel N-1 (allyloxymethyl) analogues of 6-benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, emivirine) with improved activity against HIV-1 and its mutants.
    El-Brollosy NR; Jørgensen PT; Dahan B; Boel AM; Pedersen EB; Nielsen C
    J Med Chem; 2002 Dec; 45(26):5721-6. PubMed ID: 12477355
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of 6-arylvinyl analogues of the HIV drugs SJ-3366 and Emivirine.
    Wamberg M; Pedersen EB; El-Brollosy NR; Nielsen C
    Bioorg Med Chem; 2004 Mar; 12(5):1141-9. PubMed ID: 14980626
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of 6-(3,5-dichlorobenzyl) derivatives as isosteric analogues of the HIV drug 6-(3,5-dimethylbenzyl)-1-(ethoxymethyl)-5-isopropyluracil (GCA-186).
    Sørensen ER; El-Brollosy NR; Jørgensen PT; Pedersen EB; Nielsen C
    Arch Pharm (Weinheim); 2005 Jul; 338(7):299-304. PubMed ID: 15996003
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Allosteric inhibitors against HIV-1 reverse transcriptase: design and synthesis of MKC-442 analogues having an omega-functionalized acyclic structure.
    Tanaka H; Walker RT; Hopkins AL; Ren J; Jones EY; Fujimoto K; Hayashi M; Miyasaka T; Baba M; Stammers DK; Stuart DI
    Antivir Chem Chemother; 1998 Jul; 9(4):325-32. PubMed ID: 9875411
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 4-Benzyl and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones: in vitro evaluation of new C-3-amino-substituted and C-5,6-alkyl-substituted analogues against clinically important HIV mutant strains.
    Benjahad A; Croisy M; Monneret C; Bisagni E; Mabire D; Coupa S; Poncelet A; Csoka I; Guillemont J; Meyer C; Andries K; Pauwels R; de Béthune MP; Himmel DM; Das K; Arnold E; Nguyen CH; Grierson DS
    J Med Chem; 2005 Mar; 48(6):1948-64. PubMed ID: 15771439
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and antiviral evaluation of 6-(trifluoromethylbenzyl) and 6-(fluorobenzyl) analogues of HIV drugs emivirine and GCA-186.
    El-Brollosy NR; Sørensen ER; Pedersen EB; Sanna G; La Colla P; Loddo R
    Arch Pharm (Weinheim); 2008 Jan; 341(1):9-19. PubMed ID: 18161905
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and antiviral activity of new dimeric inhibitors against HIV-1.
    Danel K; Larsen LM; Pedersen EB; Sanna G; La Colla P; Loddo R
    Bioorg Med Chem; 2008 Jan; 16(1):511-7. PubMed ID: 17904371
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nonnucleoside HIV-1 reverse transcriptase inhibitors; part 3. Synthesis and antiviral activity of 5-alkyl-2-[(aryl and alkyloxyl-carbonylmethyl)thio]-6-(1-naphthylmethyl) pyrimidin-4(3H)-ones.
    He Y; Chen F; Yu X; Wang Y; De Clercq E; Balzarini J; Pannecouque C
    Bioorg Chem; 2004 Dec; 32(6):536-48. PubMed ID: 15530994
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Non-nucleoside HIV-1 reverse-transcriptase inhibitors. Part 10. Synthesis and anti-HIV activity of 5-alkyl-6-(1-naphthylmethyl)pyrimidin-4(3H)-ones with a mono- or disubstituted 2-amino function as novel 'dihydro-alkoxy-benzyl-oxopyrimidine' (DABO) analogues.
    Wang Y; Chen FE; Balzarini J; De Clercq E; Pannecouque C
    Chem Biodivers; 2008 Jan; 5(1):168-76. PubMed ID: 18205120
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of novel uracil non-nucleoside derivatives as potential reverse transcriptase inhibitors of HIV-1.
    El-Brollosy NR; Al-Deeb OA; El-Emam AA; Pedersen EB; La Colla P; Collu G; Sanna G; Loddo R
    Arch Pharm (Weinheim); 2009 Nov; 342(11):663-70. PubMed ID: 19856332
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of 2-(aminocarbonylmethylthio)-1H-imidazoles as novel Capravirine analogues.
    Loksha YM; el-Barbary AA; el-Badawi MA; Nielsen C; Pedersen EB
    Bioorg Med Chem; 2005 Jul; 13(13):4209-20. PubMed ID: 15896963
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of 1-benzyl-3-(3,5-dimethylbenzyl)uracil derivatives with potential anti-HIV activity.
    Isono Y; Sakakibara N; Ordonez P; Hamasaki T; Baba M; Ikejiri M; Maruyama T
    Antivir Chem Chemother; 2011 Oct; 22(2):57-65. PubMed ID: 21984685
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and potent anti-HIV-1 activity of novel 6-benzyluracil analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine.
    Danel K; Larsen E; Pedersen EB; Vestergaard BF; Nielsen C
    J Med Chem; 1996 Jun; 39(12):2427-31. PubMed ID: 8691437
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of furoannelated analogues of Emivirine (MKC-442).
    Wamberg M; Pedersen EB; Nielsen C
    Arch Pharm (Weinheim); 2004 Mar; 337(3):148-51. PubMed ID: 15038059
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and anti-HIV activity evaluation of 1-[(alkenyl or alkynyl or alkyloxy)methyl]-5-alkyl-6-(1-naphthoyl)-2,4-pyrimidinediones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Ji L; Chen FE; Xie B; De Clercq E; Balzarini J; Pannecouque C
    Eur J Med Chem; 2007 Feb; 42(2):198-204. PubMed ID: 17095124
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Non-nucleoside HIV reverse transcriptase inhibitors, Part 6[1]: synthesis and anti-HIV activity of novel 2-[(arylcarbonylmethyl)thio]-6-arylthio DABO analogues.
    Sun GF; Kuang YY; Chen FE; De Clercq E; Balzarini J; Pannecouque C
    Arch Pharm (Weinheim); 2005 Oct; 338(10):457-61. PubMed ID: 16211654
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C variant.
    Ragno R; Mai A; Sbardella G; Artico M; Massa S; Musiu C; Mura M; Marturana F; Cadeddu A; La Colla P
    J Med Chem; 2004 Feb; 47(4):928-34. PubMed ID: 14761194
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family.
    Mai A; Artico M; Ragno R; Sbardella G; Massa S; Musiu C; Mura M; Marturana F; Cadeddu A; Maga G; La Colla P
    Bioorg Med Chem; 2005 Mar; 13(6):2065-77. PubMed ID: 15727860
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.