These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 17468513)

  • 1. Dietary flavonoids induce MLL translocations in primary human CD34+ cells.
    Barjesteh van Waalwijk van Doorn-Khosrovani S; Janssen J; Maas LM; Godschalk RW; Nijhuis JG; van Schooten FJ
    Carcinogenesis; 2007 Aug; 28(8):1703-9. PubMed ID: 17468513
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements.
    Biechonski S; Gourevich D; Rall M; Aqaqe N; Yassin M; Zipin-Roitman A; Trakhtenbrot L; Olender L; Raz Y; Jaffa AJ; Grisaru D; Wiesmuller L; Elad D; Milyavsky M
    Int J Cancer; 2017 Feb; 140(4):864-876. PubMed ID: 27813122
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MLL rearrangements are induced by low doses of etoposide in human fetal hematopoietic stem cells.
    Moneypenny CG; Shao J; Song Y; Gallagher EP
    Carcinogenesis; 2006 Apr; 27(4):874-81. PubMed ID: 16377807
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bioflavonoids promote stable translocations between MLL-AF9 breakpoint cluster regions independent of normal chromosomal context: Model system to screen environmental risks.
    Bariar B; Vestal CG; Deem B; Goodenow D; Ughetta M; Engledove RW; Sahyouni M; Richardson C
    Environ Mol Mutagen; 2019 Mar; 60(2):154-167. PubMed ID: 30387535
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bioflavonoids cause DNA double-strand breaks and chromosomal translocations through topoisomerase II-dependent and -independent mechanisms.
    Goodenow D; Emmanuel F; Berman C; Sahyouni M; Richardson C
    Mutat Res Genet Toxicol Environ Mutagen; 2020 Jan; 849():503144. PubMed ID: 32087851
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prenatal exposure to flavonoids: implication for cancer risk.
    Vanhees K; de Bock L; Godschalk RW; van Schooten FJ; van Waalwijk van Doorn-Khosrovani SB
    Toxicol Sci; 2011 Mar; 120(1):59-67. PubMed ID: 21177254
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Therapy-related acute myeloid leukemia-like MLL rearrangements are induced by etoposide in primary human CD34+ cells and remain stable after clonal expansion.
    Libura J; Slater DJ; Felix CA; Richardson C
    Blood; 2005 Mar; 105(5):2124-31. PubMed ID: 15528316
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia.
    Strick R; Strissel PL; Borgers S; Smith SL; Rowley JD
    Proc Natl Acad Sci U S A; 2000 Apr; 97(9):4790-5. PubMed ID: 10758153
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Etoposide and illegitimate DNA double-strand break repair in the generation of MLL translocations: new insights and new questions.
    Sung PA; Libura J; Richardson C
    DNA Repair (Amst); 2006 Sep; 5(9-10):1109-18. PubMed ID: 16809075
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity.
    Cowell IG; Sondka Z; Smith K; Lee KC; Manville CM; Sidorczuk-Lesthuruge M; Rance HA; Padget K; Jackson GH; Adachi N; Austin CA
    Proc Natl Acad Sci U S A; 2012 Jun; 109(23):8989-94. PubMed ID: 22615413
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chlorpyrifos Induces MLL Translocations Through Caspase 3-Dependent Genomic Instability and Topoisomerase II Inhibition in Human Fetal Liver Hematopoietic Stem Cells.
    Lu C; Liu X; Liu C; Wang J; Li C; Liu Q; Li Y; Li S; Sun S; Yan J; Shao J
    Toxicol Sci; 2015 Oct; 147(2):588-606. PubMed ID: 26198043
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The broken MLL gene is frequently located outside the inherent chromosome territory in human lymphoid cells treated with DNA topoisomerase II poison etoposide.
    Glukhov SI; Rubtsov MA; Alexeyevsky DA; Alexeevski AV; Razin SV; Iarovaia OV
    PLoS One; 2013; 8(9):e75871. PubMed ID: 24086652
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chromosomal translocations involving the MLL gene: molecular mechanisms.
    Aplan PD
    DNA Repair (Amst); 2006 Sep; 5(9-10):1265-72. PubMed ID: 16797254
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Etoposide induces MLL rearrangements and other chromosomal abnormalities in human embryonic stem cells.
    Bueno C; Catalina P; Melen GJ; Montes R; Sánchez L; Ligero G; García-Pérez JL; Menendez P
    Carcinogenesis; 2009 Sep; 30(9):1628-37. PubMed ID: 19587093
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular analysis of 13 cases of MLL/11q23 secondary acute leukemia and identification of topoisomerase II consensus-binding sequences near the chromosomal breakpoint of a secondary leukemia with the t(4;11).
    Domer PH; Head DR; Renganathan N; Raimondi SC; Yang E; Atlas M
    Leukemia; 1995 Aug; 9(8):1305-12. PubMed ID: 7643617
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Etoposide-initiated MLL rearrangements detected at high frequency in human primitive hematopoietic stem cells with in vitro and in vivo long-term repopulating potential.
    Libura J; Ward M; Solecka J; Richardson C
    Eur J Haematol; 2008 Sep; 81(3):185-95. PubMed ID: 18510699
    [TBL] [Abstract][Full Text] [Related]  

  • 17.
    Schneidawind C; Jeong J; Schneidawind D; Kim IS; Duque-Afonso J; Wong SHK; Iwasaki M; Breese EH; Zehnder JL; Porteus M; Cleary ML
    Blood Adv; 2018 Apr; 2(8):832-845. PubMed ID: 29650777
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors.
    Megonigal MD; Cheung NK; Rappaport EF; Nowell PC; Wilson RB; Jones DH; Addya K; Leonard DG; Kushner BH; Williams TM; Lange BJ; Felix CA
    Proc Natl Acad Sci U S A; 2000 Mar; 97(6):2814-9. PubMed ID: 10706619
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Panhandle PCR approaches to cloning MLL genomic breakpoint junctions and fusion transcript sequences.
    Robinson BW; Felix CA
    Methods Mol Biol; 2009; 538():85-114. PubMed ID: 19277575
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Topoisomerase II and the etiology of chromosomal translocations.
    Felix CA; Kolaris CP; Osheroff N
    DNA Repair (Amst); 2006 Sep; 5(9-10):1093-108. PubMed ID: 16857431
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.