These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 17475279)

  • 1. The mechanism of inhibition of antibody-based inhibitors of membrane-type serine protease 1 (MT-SP1).
    Farady CJ; Sun J; Darragh MR; Miller SM; Craik CS
    J Mol Biol; 2007 Jun; 369(4):1041-51. PubMed ID: 17475279
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Potent and selective inhibition of membrane-type serine protease 1 by human single-chain antibodies.
    Sun J; Pons J; Craik CS
    Biochemistry; 2003 Feb; 42(4):892-900. PubMed ID: 12549907
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of an Fab-protease complex reveals a highly specific non-canonical mechanism of inhibition.
    Farady CJ; Egea PF; Schneider EL; Darragh MR; Craik CS
    J Mol Biol; 2008 Jul; 380(2):351-60. PubMed ID: 18514224
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site.
    Katz BA; Elrod K; Luong C; Rice MJ; Mackman RL; Sprengeler PA; Spencer J; Hataye J; Janc J; Link J; Litvak J; Rai R; Rice K; Sideris S; Verner E; Young W
    J Mol Biol; 2001 Apr; 307(5):1451-86. PubMed ID: 11292354
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Engineering of a macromolecular scaffold to develop specific protease inhibitors.
    Stoop AA; Craik CS
    Nat Biotechnol; 2003 Sep; 21(9):1063-8. PubMed ID: 12923547
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A reverse binding motif that contributes to specific protease inhibition by antibodies.
    Schneider EL; Lee MS; Baharuddin A; Goetz DH; Farady CJ; Ward M; Wang CI; Craik CS
    J Mol Biol; 2012 Jan; 415(4):699-715. PubMed ID: 22154938
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of alpha-lytic protease by pro region C-terminal steric occlusion of the active site.
    Sohl JL; Shiau AK; Rader SD; Wilk BJ; Agard DA
    Biochemistry; 1997 Apr; 36(13):3894-902. PubMed ID: 9092819
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue.
    Takeuchi T; Shuman MA; Craik CS
    Proc Natl Acad Sci U S A; 1999 Sep; 96(20):11054-61. PubMed ID: 10500122
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Matriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivity.
    Szabo R; Netzel-Arnett S; Hobson JP; Antalis TM; Bugge TH
    Biochem J; 2005 Aug; 390(Pt 1):231-42. PubMed ID: 15853774
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of membrane-type serine protease 1/matriptase by natural and synthetic protease inhibitors.
    Yamasaki Y; Satomi S; Murai N; Tsuzuki S; Fushiki T
    J Nutr Sci Vitaminol (Tokyo); 2003 Feb; 49(1):27-32. PubMed ID: 12882393
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-based design of inhibitors of NS3 serine protease of hepatitis C virus.
    Frecer V; Kabelác M; De Nardi P; Pricl S; Miertus S
    J Mol Graph Model; 2004 Jan; 22(3):209-20. PubMed ID: 14629979
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Conformational lability in serine protease active sites: structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B.
    Shia S; Stamos J; Kirchhofer D; Fan B; Wu J; Corpuz RT; Santell L; Lazarus RA; Eigenbrot C
    J Mol Biol; 2005 Mar; 346(5):1335-49. PubMed ID: 15713485
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Catalytic domain structures of MT-SP1/matriptase, a matrix-degrading transmembrane serine proteinase.
    Friedrich R; Fuentes-Prior P; Ong E; Coombs G; Hunter M; Oehler R; Pierson D; Gonzalez R; Huber R; Bode W; Madison EL
    J Biol Chem; 2002 Jan; 277(3):2160-8. PubMed ID: 11696548
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Improving the species cross-reactivity of an antibody using computational design.
    Farady CJ; Sellers BD; Jacobson MP; Craik CS
    Bioorg Med Chem Lett; 2009 Jul; 19(14):3744-7. PubMed ID: 19477127
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Analysis of subpocket selectivity and identification of potent selective inhibitors for matriptase and matriptase-2.
    Duchêne D; Colombo E; Désilets A; Boudreault PL; Leduc R; Marsault E; Najmanovich R
    J Med Chem; 2014 Dec; 57(23):10198-204. PubMed ID: 25387268
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thermodynamic criterion for the conformation of P1 residues of substrates and of inhibitors in complexes with serine proteinases.
    Qasim MA; Lu SM; Ding J; Bateman KS; James MN; Anderson S; Song J; Markley JL; Ganz PJ; Saunders CW; Laskowski M
    Biochemistry; 1999 Jun; 38(22):7142-50. PubMed ID: 10353824
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-function relationship of serine protease-protein inhibitor interaction.
    Otlewski J; Jaskólski M; Buczek O; Cierpicki T; Czapińska H; Krowarsch D; Smalas AO; Stachowiak D; Szpineta A; Dadlez M
    Acta Biochim Pol; 2001; 48(2):419-28. PubMed ID: 11732612
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Affinity and specificity of serine endopeptidase-protein inhibitor interactions. Empirical free energy calculations based on X-ray crystallographic structures.
    Krystek S; Stouch T; Novotny J
    J Mol Biol; 1993 Dec; 234(3):661-79. PubMed ID: 8254666
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of Selective Matriptase and Hepsin Serine Protease Inhibitors: Useful Chemical Tools for Cancer Cell Biology.
    Damalanka VC; Han Z; Karmakar P; O'Donoghue AJ; La Greca F; Kim T; Pant SM; Helander J; Klefström J; Craik CS; Janetka JW
    J Med Chem; 2019 Jan; 62(2):480-490. PubMed ID: 30571119
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enzymatic characterization of membrane-associated hepatitis C virus NS3-4A heterocomplex serine protease activity expressed in human cells.
    Hamill P; Jean F
    Biochemistry; 2005 May; 44(17):6586-96. PubMed ID: 15850392
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.