BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

99 related articles for article (PubMed ID: 17483347)

  • 1. Mammalian target of rapamycin activation impairs hepatocytic differentiation and targets genes moderating lipid homeostasis and hepatocellular growth.
    Parent R; Kolippakkam D; Booth G; Beretta L
    Cancer Res; 2007 May; 67(9):4337-45. PubMed ID: 17483347
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Akt/mammalian target of rapamycin signal transduction pathway is activated in high-risk myelodysplastic syndromes and influences cell survival and proliferation.
    Follo MY; Mongiorgi S; Bosi C; Cappellini A; Finelli C; Chiarini F; Papa V; Libra M; Martinelli G; Cocco L; Martelli AM
    Cancer Res; 2007 May; 67(9):4287-94. PubMed ID: 17483341
    [TBL] [Abstract][Full Text] [Related]  

  • 3. mTOR and P70 S6 kinase expression in primary liver neoplasms.
    Sahin F; Kannangai R; Adegbola O; Wang J; Su G; Torbenson M
    Clin Cancer Res; 2004 Dec; 10(24):8421-5. PubMed ID: 15623621
    [TBL] [Abstract][Full Text] [Related]  

  • 4. V-AKT murine thymoma viral oncogene homolog/mammalian target of rapamycin activation induces a module of metabolic changes contributing to growth in insulin-induced hepatocarcinogenesis.
    Evert M; Calvisi DF; Evert K; De Murtas V; Gasparetti G; Mattu S; Destefanis G; Ladu S; Zimmermann A; Delogu S; Thiel S; Thiele A; Ribback S; Dombrowski F
    Hepatology; 2012 May; 55(5):1473-84. PubMed ID: 22271091
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mammalian target of rapamycin as a novel target in the treatment of hepatocellular carcinoma.
    Guo Y; Liang X; Lu M; Weng T; Liu Y; Ye X
    Hepatogastroenterology; 2010; 57(101):913-8. PubMed ID: 21033251
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Modulation of the activities of AMP-activated protein kinase, protein kinase B, and mammalian target of rapamycin by limiting energy availability with 2-deoxyglucose.
    Jiang W; Zhu Z; Thompson HJ
    Mol Carcinog; 2008 Aug; 47(8):616-28. PubMed ID: 18247380
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: a crucial role of AMPK and mTOR pathways.
    Chiang PC; Lin SC; Pan SL; Kuo CH; Tsai IL; Kuo MT; Wen WC; Chen P; Guh JH
    Biochem Pharmacol; 2010 Jan; 79(2):162-71. PubMed ID: 19723512
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin.
    Han J; Wang B; Xiao Z; Gao Y; Zhao Y; Zhang J; Chen B; Wang X; Dai J
    Mol Cell Neurosci; 2008 Sep; 39(1):118-24. PubMed ID: 18620060
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of mammalian target of rapamycin activity in PTEN-inactive prostate cancer cells by I kappa B kinase alpha.
    Dan HC; Adli M; Baldwin AS
    Cancer Res; 2007 Jul; 67(13):6263-9. PubMed ID: 17616684
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Akt activation protects pancreatic beta cells from AMPK-mediated death through stimulation of mTOR.
    Cai Y; Wang Q; Ling Z; Pipeleers D; McDermott P; Pende M; Heimberg H; Van de Casteele M
    Biochem Pharmacol; 2008 May; 75(10):1981-93. PubMed ID: 18377870
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression of an activated mammalian target of rapamycin in adenocarcinoma of the cervix: A potential biomarker and molecular target therapy.
    Faried LS; Faried A; Kanuma T; Aoki H; Sano T; Nakazato T; Tamura T; Kuwano H; Minegishi T
    Mol Carcinog; 2008 Jun; 47(6):446-57. PubMed ID: 18058806
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sirolimus inhibits human pancreatic carcinoma cell proliferation by a mechanism linked to the targeting of mTOR/HIF-1 alpha/VEGF signaling.
    Wang Y; Zhao Q; Ma S; Yang F; Gong Y; Ke C
    IUBMB Life; 2007 Nov; 59(11):717-21. PubMed ID: 17968710
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hepatocyte iron loading capacity is associated with differentiation and repression of motility in the HepaRG cell line.
    Troadec MB; Glaise D; Lamirault G; Le Cunff M; Guérin E; Le Meur N; Détivaud L; Zindy P; Leroyer P; Guisle I; Duval H; Gripon P; Théret N; Boudjema K; Guguen-Guillouzo C; Brissot P; Léger JJ; Loréal O
    Genomics; 2006 Jan; 87(1):93-103. PubMed ID: 16325370
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Critical and diverse involvement of Akt/mammalian target of rapamycin signaling in human lung carcinomas.
    Dobashi Y; Suzuki S; Matsubara H; Kimura M; Endo S; Ooi A
    Cancer; 2009 Jan; 115(1):107-18. PubMed ID: 19090006
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antagonism of the mammalian target of rapamycin selectively mediates metabolic effects of epidermal growth factor receptor inhibition and protects human malignant glioma cells from hypoxia-induced cell death.
    Ronellenfitsch MW; Brucker DP; Burger MC; Wolking S; Tritschler F; Rieger J; Wick W; Weller M; Steinbach JP
    Brain; 2009 Jun; 132(Pt 6):1509-22. PubMed ID: 19416948
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of mTOR radiosensitizes soft tissue sarcoma and tumor vasculature.
    Murphy JD; Spalding AC; Somnay YR; Markwart S; Ray ME; Hamstra DA
    Clin Cancer Res; 2009 Jan; 15(2):589-96. PubMed ID: 19147764
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Combination of rapamycin and 17-allylamino-17-demethoxygeldanamycin abrogates Akt activation and potentiates mTOR blockade in breast cancer cells.
    Roforth MM; Tan C
    Anticancer Drugs; 2008 Aug; 19(7):681-8. PubMed ID: 18594209
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeted therapy of human osteosarcoma with 17AAG or rapamycin: characterization of induced apoptosis and inhibition of mTOR and Akt/MAPK/Wnt pathways.
    Gazitt Y; Kolaparthi V; Moncada K; Thomas C; Freeman J
    Int J Oncol; 2009 Feb; 34(2):551-61. PubMed ID: 19148492
    [TBL] [Abstract][Full Text] [Related]  

  • 19. IGF-1-stimulated protein synthesis in oligodendrocyte progenitors requires PI3K/mTOR/Akt and MEK/ERK pathways.
    Bibollet-Bahena O; Almazan G
    J Neurochem; 2009 Jun; 109(5):1440-51. PubMed ID: 19453943
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of HIF-1alpha in exponentially growing cells via hypoxic stimulation is independent of the Akt/mTOR pathway.
    Dayan F; Bilton RL; Laferrière J; Trottier E; Roux D; Pouyssegur J; Mazure NM
    J Cell Physiol; 2009 Jan; 218(1):167-74. PubMed ID: 18781596
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.