1198 related articles for article (PubMed ID: 17485253)
1. MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents.
Kaina B; Christmann M; Naumann S; Roos WP
DNA Repair (Amst); 2007 Aug; 6(8):1079-99. PubMed ID: 17485253
[TBL] [Abstract][Full Text] [Related]
2. Development of a new application of the comet assay to assess levels of O6-methylguanine in genomic DNA (CoMeth).
Ramos AA; Pedro DF; Lima CF; Collins AR; Pereira-Wilson C
Free Radic Biol Med; 2013 Jul; 60():41-8. PubMed ID: 23391575
[TBL] [Abstract][Full Text] [Related]
3. Novel mechanism whereby nuclear factor kappaB mediates DNA damage repair through regulation of O(6)-methylguanine-DNA-methyltransferase.
Lavon I; Fuchs D; Zrihan D; Efroni G; Zelikovitch B; Fellig Y; Siegal T
Cancer Res; 2007 Sep; 67(18):8952-9. PubMed ID: 17875738
[TBL] [Abstract][Full Text] [Related]
4. Apoptosis induced by DNA damage O6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent.
Ochs K; Kaina B
Cancer Res; 2000 Oct; 60(20):5815-24. PubMed ID: 11059778
[TBL] [Abstract][Full Text] [Related]
5. O(6)-methylguanine-DNA methyltransferase (MGMT): impact on cancer risk in response to tobacco smoke.
Christmann M; Kaina B
Mutat Res; 2012 Aug; 736(1-2):64-74. PubMed ID: 21708177
[TBL] [Abstract][Full Text] [Related]
6. Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents.
Srivenugopal KS; Shou J; Mullapudi SR; Lang FF; Rao JS; Ali-Osman F
Clin Cancer Res; 2001 May; 7(5):1398-409. PubMed ID: 11350911
[TBL] [Abstract][Full Text] [Related]
7. The bacterial alkyltransferase-like (eATL) protein protects mammalian cells against methylating agent-induced toxicity.
Tomaszowski KH; Aasland D; Margison GP; Williams E; Pinder SI; Modesti M; Fuchs RP; Kaina B
DNA Repair (Amst); 2015 Apr; 28():14-20. PubMed ID: 25703834
[TBL] [Abstract][Full Text] [Related]
8. Mouse embryonic stem cells are hypersensitive to apoptosis triggered by the DNA damage O(6)-methylguanine due to high E2F1 regulated mismatch repair.
Roos WP; Christmann M; Fraser ST; Kaina B
Cell Death Differ; 2007 Aug; 14(8):1422-32. PubMed ID: 17464330
[TBL] [Abstract][Full Text] [Related]
9. Alkyltransferase-like proteins.
Margison GP; Butt A; Pearson SJ; Wharton S; Watson AJ; Marriott A; Caetano CM; Hollins JJ; Rukazenkova N; Begum G; Santibáñez-Koref MF
DNA Repair (Amst); 2007 Aug; 6(8):1222-8. PubMed ID: 17500045
[TBL] [Abstract][Full Text] [Related]
10. MGMT hypermethylation: a prognostic foe, a predictive friend.
Jacinto FV; Esteller M
DNA Repair (Amst); 2007 Aug; 6(8):1155-60. PubMed ID: 17482895
[TBL] [Abstract][Full Text] [Related]
11. No-observed effect levels are associated with up-regulation of MGMT following MMS exposure.
Doak SH; Brüsehafer K; Dudley E; Quick E; Johnson G; Newton RP; Jenkins GJ
Mutat Res; 2008 Dec; 648(1-2):9-14. PubMed ID: 18992265
[TBL] [Abstract][Full Text] [Related]
12. Alkylation damage in DNA and RNA--repair mechanisms and medical significance.
Drabløs F; Feyzi E; Aas PA; Vaagbø CB; Kavli B; Bratlie MS; Peña-Diaz J; Otterlei M; Slupphaug G; Krokan HE
DNA Repair (Amst); 2004 Nov; 3(11):1389-407. PubMed ID: 15380096
[TBL] [Abstract][Full Text] [Related]
13. Targeting of O6-MeG DNA methyltransferase (MGMT) to mitochondria protects against alkylation induced cell death.
Rasmussen AK; Rasmussen LJ
Mitochondrion; 2005 Dec; 5(6):411-7. PubMed ID: 16233991
[TBL] [Abstract][Full Text] [Related]
14. Promoter methylation of O(6)-methylguanine-DNA-methyltransferase in lung cancer is regulated by p53.
Lai JC; Cheng YW; Goan YG; Chang JT; Wu TC; Chen CY; Lee H
DNA Repair (Amst); 2008 Aug; 7(8):1352-63. PubMed ID: 18555750
[TBL] [Abstract][Full Text] [Related]
15. Role of O6-methylguanine-DNA methyltransferase in the resistance of pancreatic tumors to DNA alkylating agents.
Kokkinakis DM; Ahmed MM; Delgado R; Fruitwala MM; Mohiuddin M; Albores-Saavedra J
Cancer Res; 1997 Dec; 57(23):5360-8. PubMed ID: 9393761
[TBL] [Abstract][Full Text] [Related]
16. p53 is involved in regulation of the DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents.
Grombacher T; Eichhorn U; Kaina B
Oncogene; 1998 Aug; 17(7):845-51. PubMed ID: 9780001
[TBL] [Abstract][Full Text] [Related]
17. The L84F polymorphism in the O6-Methylguanine-DNA-Methyltransferase (MGMT) gene is associated with increased hypoxanthine phosphoribosyltransferase (HPRT) mutant frequency in lymphocytes of tobacco smokers.
Hill CE; Wickliffe JK; Guerin AT; Kinslow CJ; Wolfe KJ; Ammenheuser MM; Abdel-Rahman SZ
Pharmacogenet Genomics; 2007 Sep; 17(9):743-53. PubMed ID: 17700363
[TBL] [Abstract][Full Text] [Related]
18. Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer.
Esteller M; Herman JG
Oncogene; 2004 Jan; 23(1):1-8. PubMed ID: 14712205
[TBL] [Abstract][Full Text] [Related]
19. Epigenetic silencing of the MGMT gene in cancer.
Soejima H; Zhao W; Mukai T
Biochem Cell Biol; 2005 Aug; 83(4):429-37. PubMed ID: 16094446
[TBL] [Abstract][Full Text] [Related]
20. Loss of ATM sensitizes against O6-methylguanine triggered apoptosis, SCEs and chromosomal aberrations.
Debiak M; Nikolova T; Kaina B
DNA Repair (Amst); 2004 Apr; 3(4):359-68. PubMed ID: 15010311
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
