These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
173 related articles for article (PubMed ID: 17485500)
1. Comparative antimalarial activities of six pairs of 1,2,4,5-tetraoxanes (peroxide dimers) and 1,2,4,5,7,8-hexaoxonanes (peroxide trimers). Dong Y; Creek D; Chollet J; Matile H; Charman SA; Wittlin S; Wood JK; Vennerstrom JL Antimicrob Agents Chemother; 2007 Aug; 51(8):3033-5. PubMed ID: 17485500 [TBL] [Abstract][Full Text] [Related]
2. Comparison of the reactivity of antimalarial 1,2,4,5-tetraoxanes with 1,2,4-trioxolanes in the presence of ferrous iron salts, heme, and ferrous iron salts/phosphatidylcholine. Bousejra-El Garah F; Wong MH; Amewu RK; Muangnoicharoen S; Maggs JL; Stigliani JL; Park BK; Chadwick J; Ward SA; O'Neill PM J Med Chem; 2011 Oct; 54(19):6443-55. PubMed ID: 21888440 [TBL] [Abstract][Full Text] [Related]
3. Synthesis and antimalarial activity of dihydroperoxides and tetraoxanes conjugated with bis(benzyl)acetone derivatives. Franco LL; de Almeida MV; E Silva LF; Vieira PP; Pohlit AM; Valle MS Chem Biol Drug Des; 2012 May; 79(5):790-7. PubMed ID: 22284812 [TBL] [Abstract][Full Text] [Related]
4. Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles. Ellis GL; Amewu R; Sabbani S; Stocks PA; Shone A; Stanford D; Gibbons P; Davies J; Vivas L; Charnaud S; Bongard E; Hall C; Rimmer K; Lozanom S; Jesús M; Gargallo D; Ward SA; O'Neill PM J Med Chem; 2008 Apr; 51(7):2170-7. PubMed ID: 18341274 [TBL] [Abstract][Full Text] [Related]
5. Tetraoxanes as antimalarials: harnessing the endoperoxide. Fisher LC; Blackie MA Mini Rev Med Chem; 2014 Feb; 14(2):123-35. PubMed ID: 24456270 [TBL] [Abstract][Full Text] [Related]
6. Chemical stability of the peroxide bond enables diversified synthesis of potent tetraoxane antimalarials. Opsenica I; Opsenica D; Smith KS; Milhous WK; Solaja BA J Med Chem; 2008 Apr; 51(7):2261-6. PubMed ID: 18330976 [TBL] [Abstract][Full Text] [Related]
7. Dispiro-1,2,4,5-tetraoxanes: a new class of antimalarial peroxides. Vennerstrom JL; Fu HN; Ellis WY; Ager AL; Wood JK; Andersen SL; Gerena L; Milhous WK J Med Chem; 1992 Aug; 35(16):3023-7. PubMed ID: 1501229 [TBL] [Abstract][Full Text] [Related]
8. Tetraoxanes: synthetic and medicinal chemistry perspective. Kumar N; Singh R; Rawat DS Med Res Rev; 2012 May; 32(3):581-610. PubMed ID: 22675731 [TBL] [Abstract][Full Text] [Related]
11. New chimeric antimalarials with 4-aminoquinoline moiety linked to a tetraoxane skeleton. Opsenica I; Opsenica D; Lanteri CA; Anova L; Milhous WK; Smith KS; Solaja BA J Med Chem; 2008 Oct; 51(19):6216-9. PubMed ID: 18774792 [TBL] [Abstract][Full Text] [Related]
12. Comparative antimalarial activities and ADME profiles of ozonides (1,2,4-trioxolanes) OZ277, OZ439, and their 1,2-dioxolane, 1,2,4-trioxane, and 1,2,4,5-tetraoxane isosteres. Wang X; Dong Y; Wittlin S; Charman SA; Chiu FC; Chollet J; Katneni K; Mannila J; Morizzi J; Ryan E; Scheurer C; Steuten J; Santo Tomas J; Snyder C; Vennerstrom JL J Med Chem; 2013 Mar; 56(6):2547-55. PubMed ID: 23489135 [TBL] [Abstract][Full Text] [Related]
13. Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers. Amewu RK; Chadwick J; Hussain A; Panda S; Rinki R; Janneh O; Ward SA; Miguel C; Burrell-Saward H; Vivas L; O'Neill PM Bioorg Med Chem; 2013 Dec; 21(23):7392-7. PubMed ID: 24148834 [TBL] [Abstract][Full Text] [Related]
14. An efficient route into synthetically challenging bridged achiral 1,2,4,5-tetraoxanes with antimalarial activity. Ellis GL; Amewu R; Hall C; Rimmer K; Ward SA; O'Neill PM Bioorg Med Chem Lett; 2008 Mar; 18(5):1720-4. PubMed ID: 18243702 [TBL] [Abstract][Full Text] [Related]
15. 1,2,4,5-Tetraoxane derivatives/hybrids as potent antimalarial endoperoxides: Chronological advancements, structure-activity relationship (SAR) studies and future perspectives. T A AR; Rajendra TN; Suhas KP; Ippagunta SK; Chaudhary S Med Res Rev; 2024 Sep; 44(5):2266-2290. PubMed ID: 38618882 [TBL] [Abstract][Full Text] [Related]
16. Synthesis and antimalarial activity of 11 dispiro-1,2,4,5-tetraoxane analogues of WR 148999. 7,8,15,16-Tetraoxadispiro[5.2.5.2]hexadecanes substituted at the 1 and 10 positions with unsaturated and polar functional groups. Dong Y; Matile H; Chollet J; Kaminsky R; Wood JK; Vennerstrom JL J Med Chem; 1999 Apr; 42(8):1477-80. PubMed ID: 10212135 [TBL] [Abstract][Full Text] [Related]
17. Influence of stereoisomer of dispiro-1,2,4,5-tetraoxanes on their binding mode with heme and on antimalarial activity: molecular docking studies. Tonmunphean S; Wijitkosoom A; Tantirungrotechai Y Bioorg Med Chem; 2004 May; 12(9):2005-12. PubMed ID: 15080904 [TBL] [Abstract][Full Text] [Related]
18. Antimalarial and antiplasmodial activities of norneolignans. Syntheses and SAR. Skytte DM; Nielsen SF; Chen M; Zhai L; Olsen CE; Christensen SB J Med Chem; 2006 Jan; 49(1):436-40. PubMed ID: 16392829 [TBL] [Abstract][Full Text] [Related]