179 related articles for article (PubMed ID: 17489739)
1. Characterization of human pre-elafin mutants: full antipeptidase activity is essential to preserve lung tissue integrity in experimental emphysema.
Doucet A; Bouchard D; Janelle MF; Bellemare A; Gagné S; Tremblay GM; Bourbonnais Y
Biochem J; 2007 Aug; 405(3):455-63. PubMed ID: 17489739
[TBL] [Abstract][Full Text] [Related]
2. Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution.
Tsunemi M; Matsuura Y; Sakakibara S; Katsube Y
Biochemistry; 1996 Sep; 35(36):11570-6. PubMed ID: 8794736
[TBL] [Abstract][Full Text] [Related]
3. Neutrophil influx into the lungs of beige mice is followed by elastolytic damage and emphysema.
Cavarra E; Martorana PA; de Santi M; Bartalesi B; Cortese S; Gambelli F; Lungarella G
Am J Respir Cell Mol Biol; 1999 Feb; 20(2):264-9. PubMed ID: 9922217
[TBL] [Abstract][Full Text] [Related]
4. Oxidized elafin and trappin poorly inhibit the elastolytic activity of neutrophil elastase and proteinase 3.
Nobar SM; Zani ML; Boudier C; Moreau T; Bieth JG
FEBS J; 2005 Nov; 272(22):5883-93. PubMed ID: 16279952
[TBL] [Abstract][Full Text] [Related]
5. Elafin and its precursor trappin-2 still inhibit neutrophil serine proteinases when they are covalently bound to extracellular matrix proteins by tissue transglutaminase.
Guyot N; Zani ML; Maurel MC; Dallet-Choisy S; Moreau T
Biochemistry; 2005 Nov; 44(47):15610-8. PubMed ID: 16300411
[TBL] [Abstract][Full Text] [Related]
6. Kinetics of the inhibition of neutrophil proteinases by recombinant elafin and pre-elafin (trappin-2) expressed in Pichia pastoris.
Zani ML; Nobar SM; Lacour SA; Lemoine S; Boudier C; Bieth JG; Moreau T
Eur J Biochem; 2004 Jun; 271(12):2370-8. PubMed ID: 15182352
[TBL] [Abstract][Full Text] [Related]
7. Increased local levels of granulocyte colony-stimulating factor are associated with the beneficial effect of pre-elafin (SKALP/trappin-2/WAP3) in experimental emphysema.
Janelle MF; Doucet A; Bouchard D; Bourbonnais Y; Tremblay GM
Biol Chem; 2006 Jul; 387(7):903-9. PubMed ID: 16913840
[TBL] [Abstract][Full Text] [Related]
8. Human pre-elafin inhibits a Pseudomonas aeruginosa-secreted peptidase and prevents its proliferation in complex media.
Bellemare A; Vernoux N; Morisset D; Bourbonnais Y
Antimicrob Agents Chemother; 2008 Feb; 52(2):483-90. PubMed ID: 18025118
[TBL] [Abstract][Full Text] [Related]
9. Protease inhibitors derived from elafin and SLPI and engineered to have enhanced specificity towards neutrophil serine proteases.
Zani ML; Baranger K; Guyot N; Dallet-Choisy S; Moreau T
Protein Sci; 2009 Mar; 18(3):579-94. PubMed ID: 19241385
[TBL] [Abstract][Full Text] [Related]
10. Regulation of secretory leukocyte proteinase inhibitor (SLPI) and elastase-specific inhibitor (ESI/elafin) in human airway epithelial cells by cytokines and neutrophilic enzymes.
Sallenave JM; Shulmann J; Crossley J; Jordana M; Gauldie J
Am J Respir Cell Mol Biol; 1994 Dec; 11(6):733-41. PubMed ID: 7946401
[TBL] [Abstract][Full Text] [Related]
11. Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis.
Motta JP; Magne L; Descamps D; Rolland C; Squarzoni-Dale C; Rousset P; Martin L; Cenac N; Balloy V; Huerre M; Fröhlich LF; Jenne D; Wartelle J; Belaaouaj A; Mas E; Vinel JP; Alric L; Chignard M; Vergnolle N; Sallenave JM
Gastroenterology; 2011 Apr; 140(4):1272-82. PubMed ID: 21199654
[TBL] [Abstract][Full Text] [Related]
12. Anti-inflammatory effect of pre-elafin in lipopolysaccharide-induced acute lung inflammation.
Vachon E; Bourbonnais Y; Bingle CD; Rowe SJ; Janelle MF; Tremblay GM
Biol Chem; 2002; 383(7-8):1249-56. PubMed ID: 12437112
[TBL] [Abstract][Full Text] [Related]
13. Neutrophil recruitment into the lungs is associated with increased lung elastase burden, decreased lung elastin, and emphysema in alpha 1 proteinase inhibitor-deficient mice.
Cavarra E; Martorana PA; Gambelli F; de Santi M; van Even P; Lungarella G
Lab Invest; 1996 Aug; 75(2):273-80. PubMed ID: 8765327
[TBL] [Abstract][Full Text] [Related]
14. The antimicrobial/elastase inhibitor elafin regulates lung dendritic cells and adaptive immunity.
Roghanian A; Williams SE; Sheldrake TA; Brown TI; Oberheim K; Xing Z; Howie SE; Sallenave JM
Am J Respir Cell Mol Biol; 2006 May; 34(5):634-42. PubMed ID: 16424380
[TBL] [Abstract][Full Text] [Related]
15. Secretion of mucus proteinase inhibitor and elafin by Clara cell and type II pneumocyte cell lines.
Sallenave JM; Silva A; Marsden ME; Ryle AP
Am J Respir Cell Mol Biol; 1993 Feb; 8(2):126-33. PubMed ID: 8427705
[TBL] [Abstract][Full Text] [Related]
16. Is neutrophil elastase the missing link between emphysema and fibrosis? Evidence from two mouse models.
Lucattelli M; Bartalesi B; Cavarra E; Fineschi S; Lunghi B; Martorana PA; Lungarella G
Respir Res; 2005 Jul; 6(1):83. PubMed ID: 16045796
[TBL] [Abstract][Full Text] [Related]
17. Regulation of secretory leukocyte proteinase inhibitor (SLPI) production by human bronchial epithelial cells: increase of cell-associated SLPI by neutrophil elastase.
van Wetering S; van der Linden AC; van Sterkenburg MA; Rabe KF; Schalkwijk J; Hiemstra PS
J Investig Med; 2000 Sep; 48(5):359-66. PubMed ID: 10979241
[TBL] [Abstract][Full Text] [Related]
18. Pallid mice with genetic emphysema. Neutrophil elastase burden and elastin loss occur without alteration in the bronchoalveolar lavage cell population.
de Santi MM; Martorana PA; Cavarra E; Lungarella G
Lab Invest; 1995 Jul; 73(1):40-7. PubMed ID: 7603039
[TBL] [Abstract][Full Text] [Related]
19. Intratracheally-instilled antileukoprotease and alpha 1-proteinase inhibitor: effect on human neutrophil elastase-induced experimental emphysema and pulmonary localization.
Rudolphus A; Kramps JA; Mauve I; Dijkman JH
Histochem J; 1994 Oct; 26(10):817-24. PubMed ID: 7883591
[TBL] [Abstract][Full Text] [Related]
20. AZD9668: pharmacological characterization of a novel oral inhibitor of neutrophil elastase.
Stevens T; Ekholm K; Gränse M; Lindahl M; Kozma V; Jungar C; Ottosson T; Falk-Håkansson H; Churg A; Wright JL; Lal H; Sanfridson A
J Pharmacol Exp Ther; 2011 Oct; 339(1):313-20. PubMed ID: 21791628
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]