BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 17490876)

  • 1. Evaluation of 4'-substituted bicyclic pyridones as non-steroidal inhibitors of steroid 5alpha-reductase.
    McCarthy AR; Hartmann RW; Abell AD
    Bioorg Med Chem Lett; 2007 Jul; 17(13):3603-7. PubMed ID: 17490876
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design and synthesis of novel 2-pyridone peptidomimetic falcipain 2/3 inhibitors.
    Verissimo E; Berry N; Gibbons P; Cristiano ML; Rosenthal PJ; Gut J; Ward SA; O'Neill PM
    Bioorg Med Chem Lett; 2008 Jul; 18(14):4210-4. PubMed ID: 18554905
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phenylimidazole derivatives as new inhibitors of bacterial enoyl-ACP reductase FabK.
    Kitagawa H; Ozawa T; Takahata S; Iida M
    Bioorg Med Chem Lett; 2007 Sep; 17(17):4982-6. PubMed ID: 17600706
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of substituted pyrazolo[1,5-a]quinazolin-5(4H)-one as potent poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors.
    Orvieto F; Branca D; Giomini C; Jones P; Koch U; Ontoria JM; Palumbi MC; Rowley M; Toniatti C; Muraglia E
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4196-200. PubMed ID: 19541484
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Neighboring group participation. Part 15. Stereoselective synthesis of some steroidal tetrahydrooxazin-2-ones, as novel presumed inhibitors of human 5alpha-reductase.
    Wölfling J; Hackler L; Mernyák E; Schneider G; Tóth I; Szécsi M; Julesz J; Sohár P; Csámpai A
    Steroids; 2004 Jul; 69(7):451-60. PubMed ID: 15246775
    [TBL] [Abstract][Full Text] [Related]  

  • 6. New 5alpha-reductase inhibitors: in vitro and in vivo effects.
    Pérez-Ornelas V; Cabeza M; Bratoeff E; Heuze I; Sánchez M; Ramírez E; Naranjo-Rodríguez E
    Steroids; 2005 Mar; 70(3):217-24. PubMed ID: 15763601
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selective non-steroidal inhibitors of 5 alpha-reductase type 1.
    Occhiato EG; Guarna A; Danza G; Serio M
    J Steroid Biochem Mol Biol; 2004 Jan; 88(1):1-16. PubMed ID: 15026079
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel C-6 substituted and unsubstituted pregnane derivatives as 5alpha-reductase inhibitors and their effect on hamster flank organs diameter size.
    Cabeza M; Zambrano A; Heuze I; Carrizales E; Palacios A; Segura T; Valencia N; Bratoeff E
    Steroids; 2009 Oct; 74(10-11):793-802. PubMed ID: 19406144
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 3,3-diphenylpentane skeleton as a steroid skeleton substitute: novel inhibitors of human 5alpha-reductase 1.
    Hosoda S; Hashimoto Y
    Bioorg Med Chem Lett; 2007 Oct; 17(19):5414-8. PubMed ID: 17686629
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel 5alpha-reductase inhibitors: synthesis, structure-activity studies, and pharmacokinetic profile of phenoxybenzoylphenyl acetic acids.
    Salem OI; Frotscher M; Scherer C; Neugebauer A; Biemel K; Streiber M; Maas R; Hartmann RW
    J Med Chem; 2006 Jan; 49(2):748-59. PubMed ID: 16420060
    [TBL] [Abstract][Full Text] [Related]  

  • 11. First synthesis of alpha-aminoalkyl-(N-substituted)thiocarbamoyl-phosphinates: inhibitors of aminopeptidase N (APN/CD13) with the new zinc-binding group.
    Grzywa R; Oleksyszyn J
    Bioorg Med Chem Lett; 2008 Jul; 18(13):3734-6. PubMed ID: 18524593
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and activity of 8-substituted benzo[c]quinolizin-3-ones as dual inhibitors of human 5alpha-reductases 1 and 2.
    Ferrali A; Menchi G; Occhiato EG; Danza G; Mancina R; Serio M; Guarna A
    Bioorg Med Chem Lett; 2005 Jan; 15(1):145-8. PubMed ID: 15582428
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 4-(1H-indazol-5-yl)-6-phenylpyrimidin-2(1H)-one analogs as potent CDC7 inhibitors.
    Shafer CM; Lindvall M; Bellamacina C; Gesner TG; Yabannavar A; Jia W; Lin S; Walter A
    Bioorg Med Chem Lett; 2008 Aug; 18(16):4482-5. PubMed ID: 18672368
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development and evaluation of a pharmacophore model for inhibitors of aldosterone synthase (CYP11B2).
    Ulmschneider S; Negri M; Voets M; Hartmann RW
    Bioorg Med Chem Lett; 2006 Jan; 16(1):25-30. PubMed ID: 16246562
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cyclohex-1-ene carboxylic acids: synthesis and biological evaluation of novel inhibitors of human 5 alpha reductase.
    Baston E; Salem OI; Hartmann RW
    Arch Pharm (Weinheim); 2003 Mar; 336(1):31-8. PubMed ID: 12666251
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Achieving multi-isoform PI3K inhibition in a series of substituted 3,4-dihydro-2H-benzo[1,4]oxazines.
    Perry B; Alexander R; Bennett G; Buckley G; Ceska T; Crabbe T; Dale V; Gowers L; Horsley H; James L; Jenkins K; Crépy K; Kulisa C; Lightfoot H; Lock C; Mack S; Morgan T; Nicolas AL; Pitt W; Sabin V; Wright S
    Bioorg Med Chem Lett; 2008 Aug; 18(16):4700-4. PubMed ID: 18644721
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Substituted 6-phenyl-2-naphthols. Potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1): design, synthesis, biological evaluation, and pharmacokinetics.
    Marchais-Oberwinkler S; Kruchten P; Frotscher M; Ziegler E; Neugebauer A; Bhoga U; Bey E; Müller-Vieira U; Messinger J; Thole H; Hartmann RW
    J Med Chem; 2008 Aug; 51(15):4685-98. PubMed ID: 18630892
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and evaluation of alpha,beta-unsaturated alpha-aryl-substituted fosmidomycin analogues as DXR inhibitors.
    Devreux V; Wiesner J; Jomaa H; Van der Eycken J; Van Calenbergh S
    Bioorg Med Chem Lett; 2007 Sep; 17(17):4920-3. PubMed ID: 17583502
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of 2-pyrimidyl-5-amidothiophenes as potent inhibitors for AKT: synthesis and SAR studies.
    Lin X; Murray JM; Rico AC; Wang MX; Chu DT; Zhou Y; Del Rosario M; Kaufman S; Ma S; Fang E; Crawford K; Jefferson AB
    Bioorg Med Chem Lett; 2006 Aug; 16(16):4163-8. PubMed ID: 16765046
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 5α-reductase inhibitors, antiviral and anti-tumor activities of some steroidal cyanopyridinone derivatives.
    Al-Mohizea AM; Al-Omar MA; Abdalla MM; Amr AG
    Int J Biol Macromol; 2012 Jan; 50(1):171-9. PubMed ID: 22057085
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.