BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 17495414)

  • 1. P450 phenotyping of the metabolism of selegiline to desmethylselegiline and methamphetamine.
    Benetton SA; Fang C; Yang YO; Alok R; Year M; Lin CC; Yeh LT
    Drug Metab Pharmacokinet; 2007 Apr; 22(2):78-87. PubMed ID: 17495414
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selegiline metabolism and cytochrome P450 enzymes: in vitro study in human liver microsomes.
    Taavitsainen P; Anttila M; Nyman L; Karnani H; Salonen JS; Pelkonen O
    Pharmacol Toxicol; 2000 May; 86(5):215-21. PubMed ID: 10862503
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CYP2B6 and CYP2C19 as the major enzymes responsible for the metabolism of selegiline, a drug used in the treatment of Parkinson's disease, as revealed from experiments with recombinant enzymes.
    Hidestrand M; Oscarson M; Salonen JS; Nyman L; Pelkonen O; Turpeinen M; Ingelman-Sundberg M
    Drug Metab Dispos; 2001 Nov; 29(11):1480-4. PubMed ID: 11602525
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytochrome P450 isozymes 3A4 and 2B6 are involved in the in vitro human metabolism of thiotepa to TEPA.
    Jacobson PA; Green K; Birnbaum A; Remmel RP
    Cancer Chemother Pharmacol; 2002 Jun; 49(6):461-7. PubMed ID: 12107550
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin.
    Heyn H; White RB; Stevens JC
    Drug Metab Dispos; 1996 Sep; 24(9):948-54. PubMed ID: 8886603
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.
    Renwick AB; Surry D; Price RJ; Lake BG; Evans DC
    Xenobiotica; 2000 Oct; 30(10):955-69. PubMed ID: 11315104
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4.
    Casabar RC; Wallace AD; Hodgson E; Rose RL
    Drug Metab Dispos; 2006 Oct; 34(10):1779-85. PubMed ID: 16855053
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selegiline pharmacokinetics are unaffected by the CYP3A4 inhibitor itraconazole.
    Kivistö KT; Wang JS; Backman JT; Nyman L; Taavitsainen P; Anttila M; Neuvonen PJ
    Eur J Clin Pharmacol; 2001 Apr; 57(1):37-42. PubMed ID: 11372588
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stereoselective metabolism of endosulfan by human liver microsomes and human cytochrome P450 isoforms.
    Lee HK; Moon JK; Chang CH; Choi H; Park HW; Park BS; Lee HS; Hwang EC; Lee YD; Liu KH; Kim JH
    Drug Metab Dispos; 2006 Jul; 34(7):1090-5. PubMed ID: 16581944
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stereo-selective metabolism of methadone by human liver microsomes and cDNA-expressed cytochrome P450s: a reconciliation.
    Chang Y; Fang WB; Lin SN; Moody DE
    Basic Clin Pharmacol Toxicol; 2011 Jan; 108(1):55-62. PubMed ID: 20825389
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabolism of (-)-fenchone by CYP2A6 and CYP2B6 in human liver microsomes.
    Miyazawa M; Gyoubu K
    Xenobiotica; 2007 Feb; 37(2):194-204. PubMed ID: 17484521
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1/*1 genotype.
    Kiang TK; Ho PC; Anari MR; Tong V; Abbott FS; Chang TK
    Toxicol Sci; 2006 Dec; 94(2):261-71. PubMed ID: 16945988
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450.
    Ghosal A; Satoh H; Thomas PE; Bush E; Moore D
    Drug Metab Dispos; 1996 Sep; 24(9):940-7. PubMed ID: 8886602
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CYP2C19 polymorphism is not important for the in vivo metabolism of selegiline.
    Laine K; Anttila M; Nyman L; Wahlberg A; Bertilsson L
    Eur J Clin Pharmacol; 2001 May; 57(2):137-42. PubMed ID: 11417445
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Species difference in stereoselective involvement of CYP3A in the mono-N-dealkylation of disopyramide.
    Zhang L; Fitzloff JF; Engel LC; Cook CS
    Xenobiotica; 2001 Feb; 31(2):73-83. PubMed ID: 11407536
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of CYP2B6 and CYP3A4 in the in vitro N-dechloroethylation of (R)- and (S)-ifosfamide in human liver microsomes.
    Granvil CP; Madan A; Sharkawi M; Parkinson A; Wainer IW
    Drug Metab Dispos; 1999 Apr; 27(4):533-41. PubMed ID: 10101149
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.
    Ramírez J; Innocenti F; Schuetz EG; Flockhart DA; Relling MV; Santucci R; Ratain MJ
    Drug Metab Dispos; 2004 Sep; 32(9):930-6. PubMed ID: 15319333
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Involvement of cytochromes P450 2D6, 2B6 and 2C19 in the metabolism of (-)-deprenyl and N-methyl,N-propargylphenylethylamine.
    Rittenbach KA; Baker GB
    Drug Metab Lett; 2007 Apr; 1(2):97-100. PubMed ID: 19356027
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of human liver microsomal CYP3A4 and CYP2B6 in catalyzing N-dechloroethylation of cyclophosphamide and ifosfamide.
    Huang Z; Roy P; Waxman DJ
    Biochem Pharmacol; 2000 Apr; 59(8):961-72. PubMed ID: 10692561
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytochrome P4502B6 and 2C9 do not metabolize midazolam: kinetic analysis and inhibition study with monoclonal antibodies.
    Hamaoka N; Oda Y; Hase I; Asada A
    Br J Anaesth; 2001 Apr; 86(4):540-4. PubMed ID: 11573629
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.