198 related articles for article (PubMed ID: 17496912)
1. KSR and CNK: two scaffolds regulating RAS-mediated RAF activation.
Clapéron A; Therrien M
Oncogene; 2007 May; 26(22):3143-58. PubMed ID: 17496912
[TBL] [Abstract][Full Text] [Related]
2. Caenorhabditis elegans CNK-1 promotes Raf activation but is not essential for Ras/Raf signaling.
Rocheleau CE; Rönnlund A; Tuck S; Sundaram MV
Proc Natl Acad Sci U S A; 2005 Aug; 102(33):11757-62. PubMed ID: 16085714
[TBL] [Abstract][Full Text] [Related]
3. A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila.
Douziech M; Sahmi M; Laberge G; Therrien M
Genes Dev; 2006 Apr; 20(7):807-19. PubMed ID: 16600912
[TBL] [Abstract][Full Text] [Related]
4. KSR is a scaffold required for activation of the ERK/MAPK module.
Roy F; Laberge G; Douziech M; Ferland-McCollough D; Therrien M
Genes Dev; 2002 Feb; 16(4):427-38. PubMed ID: 11850406
[TBL] [Abstract][Full Text] [Related]
5. Src42 binding activity regulates Drosophila RAF by a novel CNK-dependent derepression mechanism.
Laberge G; Douziech M; Therrien M
EMBO J; 2005 Feb; 24(3):487-98. PubMed ID: 15660123
[TBL] [Abstract][Full Text] [Related]
6. Kinase suppressor of RAS (KSR) amplifies the differentiation signal provided by low concentrations 1,25-dihydroxyvitamin D3.
Wang X; Studzinski GP
J Cell Physiol; 2004 Mar; 198(3):333-42. PubMed ID: 14755538
[TBL] [Abstract][Full Text] [Related]
7. Deficiency of kinase suppressor of Ras1 prevents oncogenic ras signaling in mice.
Lozano J; Xing R; Cai Z; Jensen HL; Trempus C; Mark W; Cannon R; Kolesnick R
Cancer Res; 2003 Jul; 63(14):4232-8. PubMed ID: 12874031
[TBL] [Abstract][Full Text] [Related]
8. CNK, a RAF-binding multidomain protein required for RAS signaling.
Therrien M; Wong AM; Rubin GM
Cell; 1998 Oct; 95(3):343-53. PubMed ID: 9814705
[TBL] [Abstract][Full Text] [Related]
9. KSR regulation of the Raf-MEK-ERK cascade.
Ritt DA; Daar IO; Morrison DK
Methods Enzymol; 2006; 407():224-37. PubMed ID: 16757327
[TBL] [Abstract][Full Text] [Related]
10. Bimodal regulation of RAF by CNK in Drosophila.
Douziech M; Roy F; Laberge G; Lefrançois M; Armengod AV; Therrien M
EMBO J; 2003 Oct; 22(19):5068-78. PubMed ID: 14517245
[TBL] [Abstract][Full Text] [Related]
11. Constitutive activation of the Raf-MAPK pathway causes negative feedback inhibition of Ras-PI3K-AKT and cellular arrest through the EphA2 receptor.
Menges CW; McCance DJ
Oncogene; 2008 May; 27(20):2934-40. PubMed ID: 18059341
[TBL] [Abstract][Full Text] [Related]
12. Phosphorylation of the kinase suppressor of ras by associated kinases.
Volle DJ; Fulton JA; Chaika OV; McDermott K; Huang H; Steinke LA; Lewis RE
Biochemistry; 1999 Apr; 38(16):5130-7. PubMed ID: 10213618
[TBL] [Abstract][Full Text] [Related]
13. CK2 Is a component of the KSR1 scaffold complex that contributes to Raf kinase activation.
Ritt DA; Zhou M; Conrads TP; Veenstra TD; Copeland TD; Morrison DK
Curr Biol; 2007 Jan; 17(2):179-84. PubMed ID: 17174095
[TBL] [Abstract][Full Text] [Related]
14. CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.
Rajakulendran T; Sahmi M; Kurinov I; Tyers M; Therrien M; Sicheri F
Proc Natl Acad Sci U S A; 2008 Feb; 105(8):2836-41. PubMed ID: 18287031
[TBL] [Abstract][Full Text] [Related]
15. Morphoproteomic profile of mTOR, Ras/Raf kinase/ERK, and NF-kappaB pathways in human gastric adenocarcinoma.
Feng W; Brown RE; Trung CD; Li W; Wang L; Khoury T; Alrawi S; Yao J; Xia K; Tan D
Ann Clin Lab Sci; 2008; 38(3):195-209. PubMed ID: 18715846
[TBL] [Abstract][Full Text] [Related]
16. Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf.
Lanigan TM; Liu A; Huang YZ; Mei L; Margolis B; Guan KL
FASEB J; 2003 Nov; 17(14):2048-60. PubMed ID: 14597674
[TBL] [Abstract][Full Text] [Related]
17. Integrating signals between cAMP and the RAS/RAF/MEK/ERK signalling pathways. Based on the anniversary prize of the Gesellschaft für Biochemie und Molekularbiologie Lecture delivered on 5 July 2003 at the Special FEBS Meeting in Brussels.
Dumaz N; Marais R
FEBS J; 2005 Jul; 272(14):3491-504. PubMed ID: 16008550
[TBL] [Abstract][Full Text] [Related]
18. Critical contribution of linker proteins to Raf kinase activation.
Anselmo AN; Bumeister R; Thomas JM; White MA
J Biol Chem; 2002 Feb; 277(8):5940-3. PubMed ID: 11741918
[TBL] [Abstract][Full Text] [Related]
19. Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.
Yang R; Piperdi S; Gorlick R
Clin Cancer Res; 2008 Oct; 14(20):6396-404. PubMed ID: 18927278
[TBL] [Abstract][Full Text] [Related]
20. The role of scaffold proteins in MEK/ERK signalling.
Sacks DB
Biochem Soc Trans; 2006 Nov; 34(Pt 5):833-6. PubMed ID: 17052209
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
