These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 17497760)

  • 1. Human variability in hepatic and renal elimination: implications for risk assessment.
    Dorne JL
    J Appl Toxicol; 2007; 27(5):411-20. PubMed ID: 17497760
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human variability in xenobiotic metabolism and pathway-related uncertainty factors for chemical risk assessment: a review.
    Dorne JL; Walton K; Renwick AG
    Food Chem Toxicol; 2005 Feb; 43(2):203-16. PubMed ID: 15621332
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolism, variability and risk assessment.
    Dorne JL
    Toxicology; 2010 Feb; 268(3):156-64. PubMed ID: 19932147
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impact of inter-individual differences in drug metabolism and pharmacokinetics on safety evaluation.
    Dorne JL
    Fundam Clin Pharmacol; 2004 Dec; 18(6):609-20. PubMed ID: 15548231
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The refinement of uncertainty/safety factors in risk assessment by the incorporation of data on toxicokinetic variability in humans.
    Dorne JL; Renwick AG
    Toxicol Sci; 2005 Jul; 86(1):20-6. PubMed ID: 15800035
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Physiological-model-based derivation of the adult and child pharmacokinetic intraspecies uncertainty factors for volatile organic compounds.
    Pelekis M; Gephart LA; Lerman SE
    Regul Toxicol Pharmacol; 2001 Feb; 33(1):12-20. PubMed ID: 11259175
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of diuron N-demethylation by mammalian hepatic microsomes and cDNA-expressed human cytochrome P450 enzymes.
    Abass K; Reponen P; Turpeinen M; Jalonen J; Pelkonen O
    Drug Metab Dispos; 2007 Sep; 35(9):1634-41. PubMed ID: 17576805
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation).
    Dorne JL; Walton K; Renwick AG
    Food Chem Toxicol; 2004 Mar; 42(3):397-421. PubMed ID: 14871582
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human variability and noncancer risk assessment- An analysis of the default uncertainty factor.
    Renwick AG; Lazarus NR
    Regul Toxicol Pharmacol; 1998 Feb; 27(1 Pt 2):3-20. PubMed ID: 9618319
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Assessment factors--applications in health risk assessment of chemicals.
    Falk-Filipsson A; Hanberg A; Victorin K; Warholm M; Wallén M
    Environ Res; 2007 May; 104(1):108-27. PubMed ID: 17166493
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Physiologically-based pharmacokinetic and toxicokinetic models in cancer risk assessment.
    Krishnan K; Johanson G
    J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2005; 23(1):31-53. PubMed ID: 16291521
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of the human kinetic adjustment factor for the health risk assessment of environmental contaminants.
    Valcke M; Krishnan K
    J Appl Toxicol; 2014 Mar; 34(3):227-40. PubMed ID: 24038072
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Probabilistic framework for the estimation of the adult and child toxicokinetic intraspecies uncertainty factors.
    Pelekis M; Nicolich MJ; Gauthier JS
    Risk Anal; 2003 Dec; 23(6):1239-55. PubMed ID: 14641898
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Factors contributing to interindividual variability to chemical toxicity].
    Lindeman B; Søderlund EJ; Dybing E
    Tidsskr Nor Laegeforen; 2002 Feb; 122(6):615-8. PubMed ID: 11998714
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Population effects and variability.
    Dorne JL; Amzal B; Bois F; Crépet A; Tressou J; Verger P
    Methods Mol Biol; 2012; 929():521-81. PubMed ID: 23007442
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The application of non-default uncertainty factors in the U.S. EPA's Integrated Risk Information System (IRIS). Part I: UF(L), UF(S), and "other uncertainty factors".
    Stedeford T; Zhao QJ; Dourson ML; Banasik M; Hsu CH
    J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2007; 25(3):245-79. PubMed ID: 17763048
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human clearance prediction: shifting the paradigm.
    Lavé T; Chapman K; Goldsmith P; Rowland M
    Expert Opin Drug Metab Toxicol; 2009 Sep; 5(9):1039-48. PubMed ID: 19611405
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An assessment of the impact of physico-chemical and biochemical characteristics on the human kinetic adjustment factor for systemic toxicants.
    Valcke M; Krishnan K
    Toxicology; 2011 Aug; 286(1-3):36-47. PubMed ID: 21605617
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chemical-specific adjustment factors for intraspecies variability of acetone toxicokinetics using a probabilistic approach.
    Mörk AK; Johanson G
    Toxicol Sci; 2010 Jul; 116(1):336-48. PubMed ID: 20400482
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Incorporating pharmacokinetic differences between children and adults in assessing children's risks to environmental toxicants.
    Ginsberg G; Hattis D; Sonawane B
    Toxicol Appl Pharmacol; 2004 Jul; 198(2):164-83. PubMed ID: 15236952
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.