142 related articles for article (PubMed ID: 17497760)
1. Human variability in hepatic and renal elimination: implications for risk assessment.
Dorne JL
J Appl Toxicol; 2007; 27(5):411-20. PubMed ID: 17497760
[TBL] [Abstract][Full Text] [Related]
2. Human variability in xenobiotic metabolism and pathway-related uncertainty factors for chemical risk assessment: a review.
Dorne JL; Walton K; Renwick AG
Food Chem Toxicol; 2005 Feb; 43(2):203-16. PubMed ID: 15621332
[TBL] [Abstract][Full Text] [Related]
3. Metabolism, variability and risk assessment.
Dorne JL
Toxicology; 2010 Feb; 268(3):156-64. PubMed ID: 19932147
[TBL] [Abstract][Full Text] [Related]
4. Impact of inter-individual differences in drug metabolism and pharmacokinetics on safety evaluation.
Dorne JL
Fundam Clin Pharmacol; 2004 Dec; 18(6):609-20. PubMed ID: 15548231
[TBL] [Abstract][Full Text] [Related]
5. The refinement of uncertainty/safety factors in risk assessment by the incorporation of data on toxicokinetic variability in humans.
Dorne JL; Renwick AG
Toxicol Sci; 2005 Jul; 86(1):20-6. PubMed ID: 15800035
[TBL] [Abstract][Full Text] [Related]
6. Physiological-model-based derivation of the adult and child pharmacokinetic intraspecies uncertainty factors for volatile organic compounds.
Pelekis M; Gephart LA; Lerman SE
Regul Toxicol Pharmacol; 2001 Feb; 33(1):12-20. PubMed ID: 11259175
[TBL] [Abstract][Full Text] [Related]
7. Characterization of diuron N-demethylation by mammalian hepatic microsomes and cDNA-expressed human cytochrome P450 enzymes.
Abass K; Reponen P; Turpeinen M; Jalonen J; Pelkonen O
Drug Metab Dispos; 2007 Sep; 35(9):1634-41. PubMed ID: 17576805
[TBL] [Abstract][Full Text] [Related]
8. Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation).
Dorne JL; Walton K; Renwick AG
Food Chem Toxicol; 2004 Mar; 42(3):397-421. PubMed ID: 14871582
[TBL] [Abstract][Full Text] [Related]
9. Human variability and noncancer risk assessment- An analysis of the default uncertainty factor.
Renwick AG; Lazarus NR
Regul Toxicol Pharmacol; 1998 Feb; 27(1 Pt 2):3-20. PubMed ID: 9618319
[TBL] [Abstract][Full Text] [Related]
10. Assessment factors--applications in health risk assessment of chemicals.
Falk-Filipsson A; Hanberg A; Victorin K; Warholm M; Wallén M
Environ Res; 2007 May; 104(1):108-27. PubMed ID: 17166493
[TBL] [Abstract][Full Text] [Related]
11. Physiologically-based pharmacokinetic and toxicokinetic models in cancer risk assessment.
Krishnan K; Johanson G
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2005; 23(1):31-53. PubMed ID: 16291521
[TBL] [Abstract][Full Text] [Related]
12. Characterization of the human kinetic adjustment factor for the health risk assessment of environmental contaminants.
Valcke M; Krishnan K
J Appl Toxicol; 2014 Mar; 34(3):227-40. PubMed ID: 24038072
[TBL] [Abstract][Full Text] [Related]
13. Probabilistic framework for the estimation of the adult and child toxicokinetic intraspecies uncertainty factors.
Pelekis M; Nicolich MJ; Gauthier JS
Risk Anal; 2003 Dec; 23(6):1239-55. PubMed ID: 14641898
[TBL] [Abstract][Full Text] [Related]
14. [Factors contributing to interindividual variability to chemical toxicity].
Lindeman B; Søderlund EJ; Dybing E
Tidsskr Nor Laegeforen; 2002 Feb; 122(6):615-8. PubMed ID: 11998714
[TBL] [Abstract][Full Text] [Related]
15. Population effects and variability.
Dorne JL; Amzal B; Bois F; Crépet A; Tressou J; Verger P
Methods Mol Biol; 2012; 929():521-81. PubMed ID: 23007442
[TBL] [Abstract][Full Text] [Related]
16. The application of non-default uncertainty factors in the U.S. EPA's Integrated Risk Information System (IRIS). Part I: UF(L), UF(S), and "other uncertainty factors".
Stedeford T; Zhao QJ; Dourson ML; Banasik M; Hsu CH
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2007; 25(3):245-79. PubMed ID: 17763048
[TBL] [Abstract][Full Text] [Related]
17. Human clearance prediction: shifting the paradigm.
Lavé T; Chapman K; Goldsmith P; Rowland M
Expert Opin Drug Metab Toxicol; 2009 Sep; 5(9):1039-48. PubMed ID: 19611405
[TBL] [Abstract][Full Text] [Related]
18. An assessment of the impact of physico-chemical and biochemical characteristics on the human kinetic adjustment factor for systemic toxicants.
Valcke M; Krishnan K
Toxicology; 2011 Aug; 286(1-3):36-47. PubMed ID: 21605617
[TBL] [Abstract][Full Text] [Related]
19. Chemical-specific adjustment factors for intraspecies variability of acetone toxicokinetics using a probabilistic approach.
Mörk AK; Johanson G
Toxicol Sci; 2010 Jul; 116(1):336-48. PubMed ID: 20400482
[TBL] [Abstract][Full Text] [Related]
20. Incorporating pharmacokinetic differences between children and adults in assessing children's risks to environmental toxicants.
Ginsberg G; Hattis D; Sonawane B
Toxicol Appl Pharmacol; 2004 Jul; 198(2):164-83. PubMed ID: 15236952
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
