80 related articles for article (PubMed ID: 17499504)
1. Synthesis and RET protein kinase inhibitory activity of 3-arylureidobenzylidene-indolin-2-ones.
Rizzi E; Cassinelli G; Dallavalle S; Lanzi C; Cincinelli R; Nannei R; Cuccuru G; Zunino F
Bioorg Med Chem Lett; 2007 Jul; 17(14):3962-8. PubMed ID: 17499504
[TBL] [Abstract][Full Text] [Related]
2. Synthesis, modeling, and RET protein kinase inhibitory activity of 3- and 4-substituted beta-carbolin-1-ones.
Cincinelli R; Cassinelli G; Dallavalle S; Lanzi C; Merlini L; Botta M; Tuccinardi T; Martinelli A; Penco S; Zunino F
J Med Chem; 2008 Dec; 51(24):7777-87. PubMed ID: 19053769
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of RET tyrosine kinase by SU5416.
Mologni L; Sala E; Cazzaniga S; Rostagno R; Kuoni T; Puttini M; Bain J; Cleris L; Redaelli S; Riva B; Formelli F; Scapozza L; Gambacorti-Passerini C
J Mol Endocrinol; 2006 Oct; 37(2):199-212. PubMed ID: 17032739
[TBL] [Abstract][Full Text] [Related]
4. Apoptotic cell death induction and angiogenesis inhibition in large established medullary thyroid carcinoma xenografts by Ret inhibitor RPI-1.
Petrangolini G; Cuccuru G; Lanzi C; Tortoreto M; Belluco S; Pratesi G; Cassinelli G; Zunino F
Biochem Pharmacol; 2006 Aug; 72(4):405-14. PubMed ID: 16756963
[TBL] [Abstract][Full Text] [Related]
5. An orally administered multitarget tyrosine kinase inhibitor, SU11248, is a novel potent inhibitor of thyroid oncogenic RET/papillary thyroid cancer kinases.
Kim DW; Jo YS; Jung HS; Chung HK; Song JH; Park KC; Park SH; Hwang JH; Rha SY; Kweon GR; Lee SJ; Jo KW; Shong M
J Clin Endocrinol Metab; 2006 Oct; 91(10):4070-6. PubMed ID: 16849418
[TBL] [Abstract][Full Text] [Related]
6. Structure and activity relationship of 2-(substituted benzoyl)-hydroxyindoles as novel CaMKII inhibitors.
Komiya M; Asano S; Koike N; Koga E; Igarashi J; Nakatani S; Isobe Y
Bioorg Med Chem Lett; 2011 Mar; 21(5):1456-8. PubMed ID: 21292482
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and anti-tyrosine kinase activity of 3-(substituted-benzylidene)-1, 3-dihydro-indolin derivatives: investigation of their role against p60c-Src receptor tyrosine kinase with the application of receptor docking studies.
Olgen S; Akaho E; Nebioglu D
Farmaco; 2005; 60(6-7):497-506. PubMed ID: 15927182
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and pp60c-Src tyrosine kinase inhibitory activities of novel indole-3-imine and amine derivatives substituted at N1 and C5.
Kiliç Z; Isgör YG; Olgen S
Arch Pharm (Weinheim); 2009 Jun; 342(6):333-43. PubMed ID: 19475593
[TBL] [Abstract][Full Text] [Related]
9. Inhibitors of the RET tyrosine kinase based on a 2-(alkylsulfanyl)-4-(3-thienyl)nicotinonitrile scaffold.
Brandt W; Mologni L; Preu L; Lemcke T; Gambacorti-Passerini C; Kunick C
Eur J Med Chem; 2010 Jul; 45(7):2919-27. PubMed ID: 20409618
[TBL] [Abstract][Full Text] [Related]
10. Interplay between Ret and Fap-1 regulates CD95-mediated apoptosis in medullary thyroid cancer cells.
Nicolini V; Cassinelli G; Cuccuru G; Bongarzone I; Petrangolini G; Tortoreto M; Mondellini P; Casalini P; Favini E; Zaffaroni N; Zunino F; Lanzi C
Biochem Pharmacol; 2011 Oct; 82(7):778-88. PubMed ID: 21741956
[TBL] [Abstract][Full Text] [Related]
11. BAY 43-9006 inhibition of oncogenic RET mutants.
Carlomagno F; Anaganti S; Guida T; Salvatore G; Troncone G; Wilhelm SM; Santoro M
J Natl Cancer Inst; 2006 Mar; 98(5):326-34. PubMed ID: 16507829
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and biological evaluation of diversely substituted indolin-2-ones.
Bouchikhi F; Rossignol E; Sancelme M; Aboab B; Anizon F; Fabbro D; Prudhomme M; Moreau P
Eur J Med Chem; 2008 Nov; 43(11):2316-22. PubMed ID: 18313174
[TBL] [Abstract][Full Text] [Related]
13. Novel aminomethylindole derivatives as inhibitors of pp60c-Src tyrosine kinase: synthesis and biological activity.
Işgör YG; Kiliç Z; Olgen S
Chem Biol Drug Des; 2008 Dec; 72(6):599-604. PubMed ID: 19090928
[TBL] [Abstract][Full Text] [Related]
14. Structural modification of an EGFR inhibitor that showed weak off-target activity against RET leading to the discovery of a potent RET inhibitor.
Sun QZ; Xu Y; Liu JJ; Zhang CH; Wang ZR; Zheng RL; Wang WJ; Li LL; Yang SY
Mol Divers; 2014 May; 18(2):403-9. PubMed ID: 24515340
[TBL] [Abstract][Full Text] [Related]
15. A redox-linked novel pathway for arsenic-mediated RET tyrosine kinase activation.
Kato M; Takeda K; Hossain K; Thang ND; Kaneko Y; Kumasaka M; Yamanoshita O; Uemura N; Takahashi M; Ohgami N; Kawamoto Y
J Cell Biochem; 2010 May; 110(2):399-407. PubMed ID: 20235151
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and evaluation of novel 7-azaindazolyl-indolyl-maleimide derivatives as antitumor agents and protein kinase C inhibitors.
Ye Q; Cao J; Zhou X; Lv D; He Q; Yang B; Hu Y
Bioorg Med Chem; 2009 Jul; 17(13):4763-72. PubMed ID: 19447039
[TBL] [Abstract][Full Text] [Related]
17. Antitumor activities of the targeted multi-tyrosine kinase inhibitor lenvatinib (E7080) against RET gene fusion-driven tumor models.
Okamoto K; Kodama K; Takase K; Sugi NH; Yamamoto Y; Iwata M; Tsuruoka A
Cancer Lett; 2013 Oct; 340(1):97-103. PubMed ID: 23856031
[TBL] [Abstract][Full Text] [Related]
18. Identification and synthesis of N'-(2-oxoindolin-3-ylidene)hydrazide derivatives against c-Met kinase.
Liang Z; Zhang D; Ai J; Chen L; Wang H; Kong X; Zheng M; Liu H; Luo C; Geng M; Jiang H; Chen K
Bioorg Med Chem Lett; 2011 Jun; 21(12):3749-54. PubMed ID: 21561768
[TBL] [Abstract][Full Text] [Related]
19. Synthesis, structure-activity relationship and crystallographic studies of 3-substituted indolin-2-one RET inhibitors.
Mologni L; Rostagno R; Brussolo S; Knowles PP; Kjaer S; Murray-Rust J; Rosso E; Zambon A; Scapozza L; McDonald NQ; Lucchini V; Gambacorti-Passerini C
Bioorg Med Chem; 2010 Feb; 18(4):1482-96. PubMed ID: 20117004
[TBL] [Abstract][Full Text] [Related]
20. Tyrosine kinase inhibitors. 6. Structure-activity relationships among N- and 3-substituted 2,2'-diselenobis(1H-indoles) for inhibition of protein tyrosine kinases and comparative in vitro and in vivo studies against selected sulfur congeners.
Showalter HD; Sercel AD; Leja BM; Wolfangel CD; Ambroso LA; Elliott WL; Fry DW; Kraker AJ; Howard CT; Lu GH; Moore CW; Nelson JM; Roberts BJ; Vincent PW; Denny WA; Thompson AM
J Med Chem; 1997 Feb; 40(4):413-26. PubMed ID: 9046331
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]