152 related articles for article (PubMed ID: 17500047)
1. Novel role of triazenes in haematological malignancies: pilot study of Temozolomide, Lomeguatrib and IL-2 in the chemo-immunotherapy of acute leukaemia.
Caporaso P; Turriziani M; Venditti A; Marchesi F; Buccisano F; Tirindelli MC; Alvino E; Garbin A; Tortorelli G; Toppo L; Bonmassar E; D'Atri S; Amadori S
DNA Repair (Amst); 2007 Aug; 6(8):1179-86. PubMed ID: 17500047
[TBL] [Abstract][Full Text] [Related]
2. O6-(4-bromothenyl)guanine (PaTrin-2), a novel inhibitor of O6-alkylguanine DNA alkyl-transferase, increases the inhibitory activity of temozolomide against human acute leukaemia cells in vitro.
Turriziani M; Caporaso P; Bonmassar L; Buccisano F; Amadori S; Venditti A; Cantonetti M; D'Atri S; Bonmassar E
Pharmacol Res; 2006 Apr; 53(4):317-23. PubMed ID: 16412662
[TBL] [Abstract][Full Text] [Related]
3. Triazene compounds in the treatment of acute myeloid leukemia: a short review and a case report.
Bonmassar L; Marchesi F; Pascale E; Franzese O; Margison GP; Bianchi A; D'Atri S; Bernardini S; Lattuada D; Bonmassar E; Aquino A
Curr Med Chem; 2013; 20(19):2389-401. PubMed ID: 23521681
[TBL] [Abstract][Full Text] [Related]
4. Triazene compounds: mechanism of action and related DNA repair systems.
Marchesi F; Turriziani M; Tortorelli G; Avvisati G; Torino F; De Vecchis L
Pharmacol Res; 2007 Oct; 56(4):275-87. PubMed ID: 17897837
[TBL] [Abstract][Full Text] [Related]
5. Multidrug Efflux Pumps Attenuate the Effect of MGMT Inhibitors.
Tomaszowski KH; Schirrmacher R; Kaina B
Mol Pharm; 2015 Nov; 12(11):3924-34. PubMed ID: 26379107
[TBL] [Abstract][Full Text] [Related]
6. Targeting methylguanine-DNA methyltransferase in the treatment of neuroblastoma.
Wagner LM; McLendon RE; Yoon KJ; Weiss BD; Billups CA; Danks MK
Clin Cancer Res; 2007 Sep; 13(18 Pt 1):5418-25. PubMed ID: 17875772
[TBL] [Abstract][Full Text] [Related]
7. A single cycle of treatment with temozolomide, alone or combined with O(6)-benzylguanine, induces strong chemoresistance in melanoma cell clones in vitro: role of O(6)-methylguanine-DNA methyltransferase and the mismatch repair system.
Alvino E; Castiglia D; Caporali S; Pepponi R; Caporaso P; Lacal PM; Marra G; Fischer F; Zambruno G; Bonmassar E; Jiricny J; D'Atri S
Int J Oncol; 2006 Oct; 29(4):785-97. PubMed ID: 16964376
[TBL] [Abstract][Full Text] [Related]
8. Lipoic acid inhibits the DNA repair protein O 6-methylguanine-DNA methyltransferase (MGMT) and triggers its depletion in colorectal cancer cells with concomitant autophagy induction.
Göder A; Nagel G; Kraus A; Dörsam B; Seiwert N; Kaina B; Fahrer J
Carcinogenesis; 2015 Aug; 36(8):817-31. PubMed ID: 25998848
[TBL] [Abstract][Full Text] [Related]
9. Phase II study of targeted therapy with temozolomide in acute myeloid leukaemia and high-risk myelodysplastic syndrome patients pre-screened for low O(6) -methylguanine DNA methyltransferase expression.
Brandwein JM; Kassis J; Leber B; Hogge D; Howson-Jan K; Minden MD; Galarneau A; Pouliot JF
Br J Haematol; 2014 Dec; 167(5):664-70. PubMed ID: 25160658
[TBL] [Abstract][Full Text] [Related]
10. Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours.
von Bueren AO; Bacolod MD; Hagel C; Heinimann K; Fedier A; Kordes U; Pietsch T; Koster J; Grotzer MA; Friedman HS; Marra G; Kool M; Rutkowski S
Br J Cancer; 2012 Oct; 107(8):1399-408. PubMed ID: 22976800
[TBL] [Abstract][Full Text] [Related]
11. Lomeguatrib, a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase: phase I safety, pharmacodynamic, and pharmacokinetic trial and evaluation in combination with temozolomide in patients with advanced solid tumors.
Ranson M; Middleton MR; Bridgewater J; Lee SM; Dawson M; Jowle D; Halbert G; Waller S; McGrath H; Gumbrell L; McElhinney RS; Donnelly D; McMurry TB; Margison GP
Clin Cancer Res; 2006 Mar; 12(5):1577-84. PubMed ID: 16533784
[TBL] [Abstract][Full Text] [Related]
12. Chemotherapeutic resistance in anaplastic astrocytoma cell lines treated with a temozolomide-lomeguatrib combination.
Ugur HC; Taspinar M; Ilgaz S; Sert F; Canpinar H; Rey JA; Castresana JS; Sunguroglu A
Mol Biol Rep; 2014 Feb; 41(2):697-703. PubMed ID: 24368590
[TBL] [Abstract][Full Text] [Related]
13. MGMT inhibitors--The Trinity College-Paterson Institute experience, a chemist's perception.
McMurry TB
DNA Repair (Amst); 2007 Aug; 6(8):1161-9. PubMed ID: 17485250
[TBL] [Abstract][Full Text] [Related]
14. A novel approach to overcome temozolomide resistance in glioma and melanoma: Inactivation of MGMT by gene therapy.
Jiang G; Wei ZP; Pei DS; Xin Y; Liu YQ; Zheng JN
Biochem Biophys Res Commun; 2011 Mar; 406(3):311-4. PubMed ID: 21329652
[TBL] [Abstract][Full Text] [Related]
15. The P140K mutant of human O(6)-methylguanine-DNA-methyltransferase (MGMT) confers resistance in vitro and in vivo to temozolomide in combination with the novel MGMT inactivator O(6)-(4-bromothenyl)guanine.
Woolford LB; Southgate TD; Margison GP; Milsom MD; Fairbairn LJ
J Gene Med; 2006 Jan; 8(1):29-34. PubMed ID: 16075413
[TBL] [Abstract][Full Text] [Related]
16. Drug-induced xenogenization of tumors: A possible role in the immune control of malignant cell growth in the brain?
Franzese O; Battaini F; Graziani G; Tentori L; Barbaccia ML; Aquino A; Roselli M; Fuggetta MP; Bonmassar E; Torino F
Pharmacol Res; 2018 May; 131():1-6. PubMed ID: 29530602
[TBL] [Abstract][Full Text] [Related]
17. Biochemical correlates of temozolomide sensitivity in pediatric solid tumor xenograft models.
Middlemas DS; Stewart CF; Kirstein MN; Poquette C; Friedman HS; Houghton PJ; Brent TP
Clin Cancer Res; 2000 Mar; 6(3):998-1007. PubMed ID: 10741727
[TBL] [Abstract][Full Text] [Related]
18. Sensitization of pancreatic tumor xenografts to carmustine and temozolomide by inactivation of their O6-Methylguanine-DNA methyltransferase with O6-benzylguanine or O6-benzyl-2'-deoxyguanosine.
Kokkinakis DM; Ahmed MM; Chendil D; Moschel RC; Pegg AE
Clin Cancer Res; 2003 Sep; 9(10 Pt 1):3801-7. PubMed ID: 14506174
[TBL] [Abstract][Full Text] [Related]
19. The role of temozolomide in the treatment of aggressive pituitary tumors.
Liu JK; Patel J; Eloy JA
J Clin Neurosci; 2015 Jun; 22(6):923-9. PubMed ID: 25772801
[TBL] [Abstract][Full Text] [Related]
20. MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
Donson AM; Addo-Yobo SO; Handler MH; Gore L; Foreman NK
Pediatr Blood Cancer; 2007 Apr; 48(4):403-7. PubMed ID: 16609952
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
