297 related articles for article (PubMed ID: 17500064)
21. The peroxisome proliferator-activated receptor beta/delta agonist, GW501516, regulates the expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells.
Dressel U; Allen TL; Pippal JB; Rohde PR; Lau P; Muscat GE
Mol Endocrinol; 2003 Dec; 17(12):2477-93. PubMed ID: 14525954
[TBL] [Abstract][Full Text] [Related]
22. Selective PPARdelta agonist treatment increases skeletal muscle lipid metabolism without altering mitochondrial energy coupling: an in vivo magnetic resonance spectroscopy study.
Jucker BM; Yang D; Casey WM; Olzinski AR; Williams C; Lenhard SC; Legos JJ; Hawk CT; Sarkar SK; Newsholme SJ
Am J Physiol Endocrinol Metab; 2007 Nov; 293(5):E1256-64. PubMed ID: 17726146
[TBL] [Abstract][Full Text] [Related]
23. Ligand-Activated Peroxisome Proliferator-Activated Receptor δ Attenuates Vascular Oxidative Stress by Inhibiting Thrombospondin-1 Expression.
Ahn MY; Ham SA; Yoo T; Lee WJ; Hwang JS; Paek KS; Lim DS; Han SG; Lee CH; Seo HG
J Vasc Res; 2018; 55(2):75-86. PubMed ID: 29408825
[TBL] [Abstract][Full Text] [Related]
24. Improved insulin sensitivity and islet function after PPARdelta activation in diabetic db/db mice.
Winzell MS; Wulff EM; Olsen GS; Sauerberg P; Gotfredsen CF; Ahrén B
Eur J Pharmacol; 2010 Jan; 626(2-3):297-305. PubMed ID: 19818749
[TBL] [Abstract][Full Text] [Related]
25. Activation of PPARdelta up-regulates fatty acid oxidation and energy uncoupling genes of mitochondria and reduces palmitate-induced apoptosis in pancreatic beta-cells.
Wan J; Jiang L; Lü Q; Ke L; Li X; Tong N
Biochem Biophys Res Commun; 2010 Jan; 391(3):1567-72. PubMed ID: 20040361
[TBL] [Abstract][Full Text] [Related]
26. Roles of PPAR delta in lipid absorption and metabolism: a new target for the treatment of type 2 diabetes.
Luquet S; Gaudel C; Holst D; Lopez-Soriano J; Jehl-Pietri C; Fredenrich A; Grimaldi PA
Biochim Biophys Acta; 2005 May; 1740(2):313-7. PubMed ID: 15949697
[TBL] [Abstract][Full Text] [Related]
27. Activation of PPARδ signaling improves skeletal muscle oxidative metabolism and endurance function in an animal model of ischemic left ventricular dysfunction.
Zizola C; Kennel PJ; Akashi H; Ji R; Castillero E; George I; Homma S; Schulze PC
Am J Physiol Heart Circ Physiol; 2015 May; 308(9):H1078-85. PubMed ID: 25713305
[TBL] [Abstract][Full Text] [Related]
28. BAIBA attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK-PPARδ-dependent pathway in mice.
Jung TW; Hwang HJ; Hong HC; Yoo HJ; Baik SH; Choi KM
Diabetologia; 2015 Sep; 58(9):2096-105. PubMed ID: 26105792
[TBL] [Abstract][Full Text] [Related]
29. Sirtuin 1 Mediates the Actions of Peroxisome Proliferator-Activated Receptor δ on the Oxidized Low-Density Lipoprotein-Triggered Migration and Proliferation of Vascular Smooth Muscle Cells.
Hwang JS; Ham SA; Yoo T; Lee WJ; Paek KS; Lee CH; Seo HG
Mol Pharmacol; 2016 Nov; 90(5):522-529. PubMed ID: 27573670
[TBL] [Abstract][Full Text] [Related]
30. PPAR{delta} agonism activates fatty acid oxidation via PGC-1{alpha} but does not increase mitochondrial gene expression and function.
Kleiner S; Nguyen-Tran V; Baré O; Huang X; Spiegelman B; Wu Z
J Biol Chem; 2009 Jul; 284(28):18624-33. PubMed ID: 19435887
[TBL] [Abstract][Full Text] [Related]
31. Metformin inhibits PPARδ agonist-mediated tumor growth by reducing Glut1 and SLC1A5 expressions of cancer cells.
Ding J; Gou Q; Jin J; Shi J; Liu Q; Hou Y
Eur J Pharmacol; 2019 Aug; 857():172425. PubMed ID: 31150647
[TBL] [Abstract][Full Text] [Related]
32. An ethanol extract of Artemisia iwayomogi activates PPARδ leading to activation of fatty acid oxidation in skeletal muscle.
Cho SY; Jeong HW; Sohn JH; Seo DB; Kim WG; Lee SJ
PLoS One; 2012; 7(3):e33815. PubMed ID: 22479450
[TBL] [Abstract][Full Text] [Related]
33. Peroxisome proliferator-activated receptor delta-agonist, GW501516, ameliorates insulin resistance, improves dyslipidaemia in monosodium L-glutamate metabolic syndrome mice.
Chen W; Wang LL; Liu HY; Long L; Li S
Basic Clin Pharmacol Toxicol; 2008 Sep; 103(3):240-6. PubMed ID: 18684227
[TBL] [Abstract][Full Text] [Related]
34. PPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunction.
Ravnskjaer K; Frigerio F; Boergesen M; Nielsen T; Maechler P; Mandrup S
J Lipid Res; 2010 Jun; 51(6):1370-9. PubMed ID: 19965574
[TBL] [Abstract][Full Text] [Related]
35. CD36-dependent regulation of muscle FoxO1 and PDK4 in the PPAR delta/beta-mediated adaptation to metabolic stress.
Nahlé Z; Hsieh M; Pietka T; Coburn CT; Grimaldi PA; Zhang MQ; Das D; Abumrad NA
J Biol Chem; 2008 May; 283(21):14317-26. PubMed ID: 18308721
[TBL] [Abstract][Full Text] [Related]
36. Genistein stimulates fatty acid oxidation in a leptin receptor-independent manner through the JAK2-mediated phosphorylation and activation of AMPK in skeletal muscle.
Palacios-González B; Zarain-Herzberg A; Flores-Galicia I; Noriega LG; Alemán-Escondrillas G; Zariñan T; Ulloa-Aguirre A; Torres N; Tovar AR
Biochim Biophys Acta; 2014 Jan; 1841(1):132-40. PubMed ID: 24013029
[TBL] [Abstract][Full Text] [Related]
37. Protein kinase N2 regulates AMP kinase signaling and insulin responsiveness of glucose metabolism in skeletal muscle.
Ruby MA; Riedl I; Massart J; Åhlin M; Zierath JR
Am J Physiol Endocrinol Metab; 2017 Oct; 313(4):E483-E491. PubMed ID: 28720584
[TBL] [Abstract][Full Text] [Related]
38. A metabolomic study of the PPARδ agonist GW501516 for enhancing running endurance in Kunming mice.
Chen W; Gao R; Xie X; Zheng Z; Li H; Li S; Dong F; Wang L
Sci Rep; 2015 May; 5():9884. PubMed ID: 25943561
[TBL] [Abstract][Full Text] [Related]
39. Increase of peroxisome proliferator-activated receptor δ (PPARδ) by digoxin to improve lipid metabolism in the heart of diabetic rats.
Chen ZC; Yu BC; Chen LJ; Cheng JT
Horm Metab Res; 2013 May; 45(5):364-71. PubMed ID: 23225238
[TBL] [Abstract][Full Text] [Related]
40. PPARdelta in humans: genetic and pharmacological evidence for a significant metabolic function.
Karpe F; Ehrenborg EE
Curr Opin Lipidol; 2009 Aug; 20(4):333-6. PubMed ID: 19512923
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
