151 related articles for article (PubMed ID: 17502122)
1. Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of pyrrolo[3,4-a]carbazole-1,3-diones, pyrrolo[3,4-c]carbazole-1,3-diones, and 2-aminopyridazino[3,4-a]pyrrolo[3,4-c]carbazole-1,3,4,7-tetraone.
Conchon E; Anizon F; Aboab B; Golsteyn RM; Léonce S; Pfeiffer B; Prudhomme M
Eur J Med Chem; 2008 Feb; 43(2):282-92. PubMed ID: 17502122
[TBL] [Abstract][Full Text] [Related]
2. Synthesis, checkpoint kinase 1 inhibitory properties and in vitro antiproliferative activities of new pyrrolocarbazoles.
Conchon E; Anizon F; Aboab B; Golsteyn RM; Léonce S; Pfeiffer B; Prudhomme M
Bioorg Med Chem; 2008 Apr; 16(8):4419-30. PubMed ID: 18321713
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and biological activities of new checkpoint kinase 1 inhibitors structurally related to granulatimide.
Conchon E; Anizon F; Aboab B; Prudhomme M
J Med Chem; 2007 Sep; 50(19):4669-80. PubMed ID: 17722905
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and structure-activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases.
Smaill JB; Lee HH; Palmer BD; Thompson AM; Squire CJ; Baker EN; Booth RJ; Kraker A; Hook K; Denny WA
Bioorg Med Chem Lett; 2008 Feb; 18(3):929-33. PubMed ID: 18191399
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and biological activities of 4-substituted pyrrolo[2,3-a]carbazole Pim kinase inhibitors.
Giraud F; Akué-Gédu R; Nauton L; Candelon N; Debiton E; Théry V; Anizon F; Moreau P
Eur J Med Chem; 2012 Oct; 56():225-36. PubMed ID: 22982527
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases.
Smaill JB; Baker EN; Booth RJ; Bridges AJ; Dickson JM; Dobrusin EM; Ivanovic I; Kraker AJ; Lee HH; Lunney EA; Ortwine DF; Palmer BD; Quin J; Squire CJ; Thompson AM; Denny WA
Eur J Med Chem; 2008 Jun; 43(6):1276-96. PubMed ID: 17869387
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and evaluation of 5-substituted 9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as check point 1 kinase inhibitors.
Sako Y; Ichikawa S; Osada A; Matsuda A
Bioorg Med Chem; 2010 Nov; 18(22):7878-89. PubMed ID: 20943405
[TBL] [Abstract][Full Text] [Related]
8. Kinase inhibitory potencies and in vitro antiproliferative activities of N-10 substituted pyrrolo[2,3-a]carbazole derivatives.
Akué-Gédu R; Letribot B; Saugues E; Debiton E; Anizon F; Moreau P
Bioorg Med Chem Lett; 2012 Jun; 22(11):3807-9. PubMed ID: 22543026
[TBL] [Abstract][Full Text] [Related]
9. Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of indolylpyrazolones and indolylpyridazinedione.
Conchon E; Aboab B; Golsteyn RM; Cruzalegui F; Edmonds T; Léonce S; Pfeiffer B; Prudhomme M
Eur J Med Chem; 2006 Dec; 41(12):1470-7. PubMed ID: 16996169
[TBL] [Abstract][Full Text] [Related]
10. Bis-imide granulatimide analogues as potent Checkpoint 1 kinase inhibitors.
Hénon H; Messaoudi S; Anizon F; Aboab B; Kucharczyk N; Léonce S; Golsteyn RM; Pfeiffer B; Prudhomme M
Eur J Pharmacol; 2007 Jan; 554(2-3):106-12. PubMed ID: 17134696
[TBL] [Abstract][Full Text] [Related]
11. Synthesis of C-glycosyl pyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as a scaffold for check point kinase 1 inhibitors.
Ichikawa S; Tatebayashi N; Matsuda A
J Org Chem; 2013 Dec; 78(23):12065-75. PubMed ID: 24127858
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new Pim kinase inhibitors.
Akué-Gédu R; Rossignol E; Azzaro S; Knapp S; Filippakopoulos P; Bullock AN; Bain J; Cohen P; Prudhomme M; Anizon F; Moreau P
J Med Chem; 2009 Oct; 52(20):6369-81. PubMed ID: 19788246
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and biological evaluation of new dipyrrolo[3,4-a:3,4-c]carbazole-1,3,4,6-tetraones, substituted with various saturated and unsaturated side chains via palladium catalyzed cross-coupling reactions.
Hénon H; Anizon F; Golsteyn RM; Léonce S; Hofmann R; Pfeiffer B; Prudhomme M
Bioorg Med Chem; 2006 Jun; 14(11):3825-34. PubMed ID: 16460946
[TBL] [Abstract][Full Text] [Related]
14. Novel 5-azaindolocarbazoles as cytotoxic agents and Chk1 inhibitors.
Lefoix M; Coudert G; Routier S; Pfeiffer B; Caignard DH; Hickman J; Pierré A; Golsteyn RM; Léonce S; Bossard C; Mérour JY
Bioorg Med Chem; 2008 May; 16(9):5303-21. PubMed ID: 18342518
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological activities of isogranulatimide analogues.
Hugon B; Anizon F; Bailly C; Golsteyn RM; Pierré A; Léonce S; Hickman J; Pfeiffer B; Prudhomme M
Bioorg Med Chem; 2007 Sep; 15(17):5965-80. PubMed ID: 17582773
[TBL] [Abstract][Full Text] [Related]
16. Synthesis, Pim kinase inhibitory potencies and in vitro antiproliferative activities of diversely substituted pyrrolo[2,3-a]carbazoles.
Akué-Gédu R; Nauton L; Théry V; Bain J; Cohen P; Anizon F; Moreau P
Bioorg Med Chem; 2010 Sep; 18(18):6865-73. PubMed ID: 20728368
[TBL] [Abstract][Full Text] [Related]
17. New N-1,N-10-bridged pyrrolo[2,3-a]carbazole-3-carbaldehydes: synthesis and biological activities.
Giraud F; Bourhis M; Nauton L; Théry V; Herfindal L; Døskeland SO; Anizon F; Moreau P
Bioorg Chem; 2014 Dec; 57():108-115. PubMed ID: 25305721
[TBL] [Abstract][Full Text] [Related]
18. Pyrrolocarbazoles as checkpoint 1 kinase inhibitors.
Hénon H; Conchon E; Hugon B; Messaoudi S; Golsteyn RM; Prudhomme M
Anticancer Agents Med Chem; 2008 Aug; 8(6):577-97. PubMed ID: 18690823
[TBL] [Abstract][Full Text] [Related]
19. Use of copper(I) catalyzed azide alkyne cycloaddition (CuAAC) for the preparation of conjugated pyrrolo[2,3-a]carbazole Pim kinase inhibitors.
Letribot B; Akué-Gédu R; Santio NM; El-Ghozzi M; Avignant D; Cisnetti F; Koskinen PJ; Gautier A; Anizon F; Moreau P
Eur J Med Chem; 2012 Apr; 50():304-10. PubMed ID: 22386260
[TBL] [Abstract][Full Text] [Related]
20. Identification of 1,6-dihydropyrazolo[4,3-c]carbazoles and 3,6-dihydropyrazolo[3,4-c]carbazoles as new Pim kinase inhibitors.
Suchaud V; Gavara L; Saugues E; Nauton L; Théry V; Anizon F; Moreau P
Bioorg Med Chem; 2013 Jul; 21(14):4102-11. PubMed ID: 23735828
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
