209 related articles for article (PubMed ID: 17508363)
1. Total synthesis of five thapsigargins: guaianolide natural products exhibiting sub-nanomolar SERCA inhibition.
Andrews SP; Ball M; Wierschem F; Cleator E; Oliver S; Högenauer K; Simic O; Antonello A; Hünger U; Smith MD; Ley SV
Chemistry; 2007; 13(20):5688-712. PubMed ID: 17508363
[TBL] [Abstract][Full Text] [Related]
2. Design and total synthesis of unnatural analogues of the sub-nanomolar SERCA inhibitor thapsigargin.
Andrews SP; Tait MM; Ball M; Ley SV
Org Biomol Chem; 2007 May; 5(9):1427-36. PubMed ID: 17464412
[TBL] [Abstract][Full Text] [Related]
3. Total synthesis of thapsigargin, a potent SERCA pump inhibitor.
Ball M; Andrews SP; Wierschem F; Cleator E; Smith MD; Ley SV
Org Lett; 2007 Feb; 9(4):663-6. PubMed ID: 17256950
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis, and development of novel guaianolide-endoperoxides as potential antimalarial agents.
Sun L; Shah F; Helal MA; Wu Y; Pedduri Y; Chittiboyina AG; Gut J; Rosenthal PJ; Avery MA
J Med Chem; 2010 Nov; 53(21):7864-8. PubMed ID: 20945914
[TBL] [Abstract][Full Text] [Related]
5. Divergent synthesis of thapsigargin analogs.
Chu H; Dünstl G; Felding J; Baran PS
Bioorg Med Chem Lett; 2018 Sep; 28(16):2705-2707. PubMed ID: 29636219
[TBL] [Abstract][Full Text] [Related]
6. Toward the synthesis of thapsigargin: enantioselective synthesis of 7,11-dihydroxyguaianolides.
Manzano FL; Guerra FM; Moreno-Dorado FJ; Jorge ZD; Massanet GM
Org Lett; 2006 Jun; 8(13):2879-82. PubMed ID: 16774280
[TBL] [Abstract][Full Text] [Related]
7. SERCA-inhibiting activity of C-19 terpenolides from Thapsia garganica and their possible biogenesis.
Appendino G; Prosperini S; Valdivia C; Ballero M; Colombano G; Billington RA; Genazzani AA; Sterner O
J Nat Prod; 2005 Aug; 68(8):1213-7. PubMed ID: 16124763
[TBL] [Abstract][Full Text] [Related]
8. Total synthesis of two novel subpicomolar sarco/endoplasmatic reticulum Ca2+-ATPase inhibitors designed by an analysis of the binding site of thapsigargin.
Søhoel H; Liljefors T; Ley SV; Oliver SF; Antonello A; Smith MD; Olsen CE; Isaacs JT; Christensen SB
J Med Chem; 2005 Nov; 48(22):7005-11. PubMed ID: 16250659
[TBL] [Abstract][Full Text] [Related]
9. A Concise, Efficient and Scalable Total Synthesis of Thapsigargin and Nortrilobolide from (R)-(-)-Carvone.
Chen D; Evans PA
J Am Chem Soc; 2017 May; 139(17):6046-6049. PubMed ID: 28422492
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and SERCA activities of structurally simplified cyclopiazonic acid analogues.
Yao S; Gallenkamp D; Wölfel K; Lüke B; Schindler M; Scherkenbeck J
Bioorg Med Chem; 2011 Aug; 19(15):4669-78. PubMed ID: 21719297
[TBL] [Abstract][Full Text] [Related]
11. Chemo- and Regioselective Functionalization of Nortrilobolide: Application for Semisynthesis of the Natural Product 2-Acetoxytrilobolide.
Doan NT; Crestey F; Olsen CE; Christensen SB
J Nat Prod; 2015 Jun; 78(6):1406-14. PubMed ID: 26078214
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase by flavonoids: a quantitative structure-activity relationship study.
Ogunbayo OA; Harris RM; Waring RH; Kirk CJ; Michelangeli F
IUBMB Life; 2008 Dec; 60(12):853-8. PubMed ID: 18785622
[TBL] [Abstract][Full Text] [Related]
13. Synthesis of the thapsigargins.
Ley SV; Antonello A; Balskus EP; Booth DT; Christensen SB; Cleator E; Gold H; Högenauer K; Hünger U; Myers RM; Oliver SF; Simic O; Smith MD; Søhoel H; Woolford AJ
Proc Natl Acad Sci U S A; 2004 Aug; 101(33):12073-8. PubMed ID: 15226504
[TBL] [Abstract][Full Text] [Related]
14. Critical roles of hydrophobicity and orientation of side chains for inactivation of sarcoplasmic reticulum Ca2+-ATPase with thapsigargin and thapsigargin analogs.
Winther AM; Liu H; Sonntag Y; Olesen C; le Maire M; Soehoel H; Olsen CE; Christensen SB; Nissen P; Møller JV
J Biol Chem; 2010 Sep; 285(37):28883-92. PubMed ID: 20551329
[TBL] [Abstract][Full Text] [Related]
15. Molecular determinants of sarco/endoplasmic reticulum calcium ATPase inhibition by hydroquinone-based compounds.
Lape M; Elam C; Versluis M; Kempton R; Paula S
Proteins; 2008 Feb; 70(3):639-49. PubMed ID: 17879345
[TBL] [Abstract][Full Text] [Related]
16. Inhibitor of sarco-endoplasmic reticulum Ca2+-ATPase thapsigargin stimulates production of nitric oxide and secretion of interferon-gamma.
Kmonícková E; Melkusová P; Harmatha J; Vokác K; Farghali H; Zídek Z
Eur J Pharmacol; 2008 Jun; 588(1):85-92. PubMed ID: 18457829
[TBL] [Abstract][Full Text] [Related]
17. From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development.
Christensen SB; Simonsen HT; Engedal N; Nissen P; Møller JV; Denmeade SR; Isaacs JT
Prog Chem Org Nat Prod; 2021; 115():59-114. PubMed ID: 33797641
[TBL] [Abstract][Full Text] [Related]
18. Synthesis of the guaianolide ring system via cycloaddition of a bicyclic carbonyl ylide with allyl propiolate.
Navickas V; Ushakov DB; Maier ME; Ströbele M; Meyer HJ
Org Lett; 2010 Aug; 12(15):3418-21. PubMed ID: 20586455
[TBL] [Abstract][Full Text] [Related]
19. Peptide inhibitors use two related mechanisms to alter the apparent calcium affinity of the sarcoplasmic reticulum calcium pump.
Afara MR; Trieber CA; Ceholski DK; Young HS
Biochemistry; 2008 Sep; 47(36):9522-30. PubMed ID: 18702513
[TBL] [Abstract][Full Text] [Related]
20. Total synthesis of englerin A.
Nicolaou KC; Kang Q; Ng SY; Chen DY
J Am Chem Soc; 2010 Jun; 132(23):8219-22. PubMed ID: 20496885
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]