BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

924 related articles for article (PubMed ID: 17511655)

  • 1. The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain.
    Stockley JH; O'Neill C
    Biochem Soc Trans; 2007 Jun; 35(Pt 3):574-6. PubMed ID: 17511655
    [TBL] [Abstract][Full Text] [Related]  

  • 2. BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein.
    Farzan M; Schnitzler CE; Vasilieva N; Leung D; Choe H
    Proc Natl Acad Sci U S A; 2000 Aug; 97(17):9712-7. PubMed ID: 10931940
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Altered beta-secretase enzyme kinetics and levels of both BACE1 and BACE2 in the Alzheimer's disease brain.
    Stockley JH; Ravid R; O'Neill C
    FEBS Lett; 2006 Dec; 580(28-29):6550-60. PubMed ID: 17113083
    [TBL] [Abstract][Full Text] [Related]  

  • 4. beta-Secretase, APP and Abeta in Alzheimer's disease.
    Vassar R
    Subcell Biochem; 2005; 38():79-103. PubMed ID: 15709474
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct transcriptional regulation and function of the human BACE2 and BACE1 genes.
    Sun X; Wang Y; Qing H; Christensen MA; Liu Y; Zhou W; Tong Y; Xiao C; Huang Y; Zhang S; Liu X; Song W
    FASEB J; 2005 May; 19(7):739-49. PubMed ID: 15857888
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.
    Sankaranarayanan S; Price EA; Wu G; Crouthamel MC; Shi XP; Tugusheva K; Tyler KX; Kahana J; Ellis J; Jin L; Steele T; Stachel S; Coburn C; Simon AJ
    J Pharmacol Exp Ther; 2008 Mar; 324(3):957-69. PubMed ID: 18156464
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression and activity of beta-site amyloid precursor protein cleaving enzyme in Alzheimer's disease.
    Johnston JA; Liu WW; Todd SA; Coulson DT; Murphy S; Irvine GB; Passmore AP
    Biochem Soc Trans; 2005 Nov; 33(Pt 5):1096-100. PubMed ID: 16246054
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) as a biological candidate marker of Alzheimer's disease.
    Hampel H; Shen Y
    Scand J Clin Lab Invest; 2009; 69(1):8-12. PubMed ID: 18609117
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lack of association between the polymorphisms of beta-site APP-cleaving enzyme 2 (BACE2) 5'-flanking region and sporadic Alzheimer's disease.
    Yu Y; Jia J
    Brain Res; 2009 Feb; 1257():10-5. PubMed ID: 19124009
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity.
    Yan R; Bienkowski MJ; Shuck ME; Miao H; Tory MC; Pauley AM; Brashier JR; Stratman NC; Mathews WR; Buhl AE; Carter DB; Tomasselli AG; Parodi LA; Heinrikson RL; Gurney ME
    Nature; 1999 Dec; 402(6761):533-7. PubMed ID: 10591213
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease.
    Rossner S; Sastre M; Bourne K; Lichtenthaler SF
    Prog Neurobiol; 2006 Jun; 79(2):95-111. PubMed ID: 16904810
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Purification and cloning of amyloid precursor protein beta-secretase from human brain.
    Sinha S; Anderson JP; Barbour R; Basi GS; Caccavello R; Davis D; Doan M; Dovey HF; Frigon N; Hong J; Jacobson-Croak K; Jewett N; Keim P; Knops J; Lieberburg I; Power M; Tan H; Tatsuno G; Tung J; Schenk D; Seubert P; Suomensaari SM; Wang S; Walker D; Zhao J; McConlogue L; John V
    Nature; 1999 Dec; 402(6761):537-40. PubMed ID: 10591214
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Decrease in brain soluble amyloid precursor protein β (sAPPβ) in Alzheimer's disease cortex.
    Wu G; Sankaranarayanan S; Hsieh SH; Simon AJ; Savage MJ
    J Neurosci Res; 2011 Jun; 89(6):822-32. PubMed ID: 21433051
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BACE1 in Alzheimer's disease.
    Sathya M; Premkumar P; Karthick C; Moorthi P; Jayachandran KS; Anusuyadevi M
    Clin Chim Acta; 2012 Dec; 414():171-8. PubMed ID: 22926063
    [TBL] [Abstract][Full Text] [Related]  

  • 16. LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.
    Majercak J; Ray WJ; Espeseth A; Simon A; Shi XP; Wolffe C; Getty K; Marine S; Stec E; Ferrer M; Strulovici B; Bartz S; Gates A; Xu M; Huang Q; Ma L; Shughrue P; Burchard J; Colussi D; Pietrak B; Kahana J; Beher D; Rosahl T; Shearman M; Hazuda D; Sachs AB; Koblan KS; Seabrook GR; Stone DJ
    Proc Natl Acad Sci U S A; 2006 Nov; 103(47):17967-72. PubMed ID: 17098871
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Beta-amyloid secretases and beta-amloid degrading enzyme expression in lens.
    Li G; Percontino L; Sun Q; Qazi AS; Frederikse PH
    Mol Vis; 2003 May; 9():179-83. PubMed ID: 12740567
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism.
    Vingtdeux V; Hamdane M; Gompel M; Bégard S; Drobecq H; Ghestem A; Grosjean ME; Kostanjevecki V; Grognet P; Vanmechelen E; Buée L; Delacourte A; Sergeant N
    Neurobiol Dis; 2005 Nov; 20(2):625-37. PubMed ID: 15936948
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of Abeta11-40/42 peptide deposition in Alzheimer's disease and young Down's syndrome brains: implication of N-terminally truncated Abeta species in the pathogenesis of Alzheimer's disease.
    Liu K; Solano I; Mann D; Lemere C; Mercken M; Trojanowski JQ; Lee VM
    Acta Neuropathol; 2006 Aug; 112(2):163-74. PubMed ID: 16865398
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting BACE with small inhibitory nucleic acids - a future for Alzheimer's disease therapy?
    Nawrot B
    Acta Biochim Pol; 2004; 51(2):431-44. PubMed ID: 15218540
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 47.