BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 17519385)

  • 1. Applicability of the dopamine and rate hypotheses in explaining the differences in behavioral pharmacology of the chloro-benztropine analogs: studies conducted using intracerebral microdialysis and population pharmacodynamic modeling.
    Othman AA; Newman AH; Eddington ND
    J Pharmacol Exp Ther; 2007 Aug; 322(2):760-9. PubMed ID: 17519385
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Behavioral and neurochemical effects of the dopamine transporter ligand 4-chlorobenztropine alone and in combination with cocaine in vivo.
    Tolliver BK; Newman AH; Katz JL; Ho LB; Fox LM; Hsu K; Berger SP
    J Pharmacol Exp Ther; 1999 Apr; 289(1):110-22. PubMed ID: 10086994
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacodynamic assessment of the benztropine analogues AHN-1055 and AHN-2005 using intracerebral microdialysis to evaluate brain dopamine levels and pharmacokinetic/pharmacodynamic modeling.
    Raje S; Cornish J; Newman AH; Cao J; Katz JL; Eddington ND
    Pharm Res; 2005 Apr; 22(4):603-12. PubMed ID: 15846468
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 3'-Chloro-3 alpha-(diphenylmethoxy)tropane but not 4'-chloro-3 alpha-(diphenylmethoxy)tropane produces a cocaine-like behavioral profile.
    Kline RH; Izenwasser S; Katz JL; Joseph DB; Bowen WD; Newman AH
    J Med Chem; 1997 Mar; 40(6):851-7. PubMed ID: 9083473
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transport, metabolism, and in vivo population pharmacokinetics of the chloro benztropine analogs, a class of compounds extensively evaluated in animal models of drug abuse.
    Othman AA; Syed SA; Newman AH; Eddington ND
    J Pharmacol Exp Ther; 2007 Jan; 320(1):344-53. PubMed ID: 17003230
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dopamine transporter binding without cocaine-like behavioral effects: synthesis and evaluation of benztropine analogs alone and in combination with cocaine in rodents.
    Katz JL; Agoston GE; Alling KL; Kline RH; Forster MJ; Woolverton WL; Kopajtic TA; Newman AH
    Psychopharmacology (Berl); 2001 Apr; 154(4):362-74. PubMed ID: 11349389
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Relations between stimulation of mesolimbic dopamine and place conditioning in rats produced by cocaine or drugs that are tolerant to dopamine transporter conformational change.
    Tanda G; Li SM; Mereu M; Thomas AM; Ebbs AL; Chun LE; Tronci V; Green JL; Zou MF; Kopajtic TA; Newman AH; Katz JL
    Psychopharmacology (Berl); 2013 Sep; 229(2):307-21. PubMed ID: 23612854
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of 4'-chloro-3 alpha-(diphenylmethoxy)-tropane on mesostriatal, mesocortical, and mesolimbic dopamine transmission: comparison with effects of cocaine.
    Tanda G; Ebbs A; Newman AH; Katz JL
    J Pharmacol Exp Ther; 2005 May; 313(2):613-20. PubMed ID: 15681658
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Investigation of the potential pharmacokinetic and pharmaco-dynamic drug interaction between AHN 1-055, a potent benztropine analog used for cocaine abuse, and cocaine after dosing in rats using intracerebral microdialysis.
    Raje S; Cornish J; Newman AH; Cao J; Katz JL; Eddington ND
    Biopharm Drug Dispos; 2006 Jul; 27(5):229-40. PubMed ID: 16586462
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 3'- and 4'-chloro-substituted analogs of benztropine: intravenous self-administration and in vitro radioligand binding studies in rhesus monkeys.
    Woolverton WL; Rowlett JK; Wilcox KM; Paul IA; Kline RH; Newman AH; Katz JL
    Psychopharmacology (Berl); 2000 Jan; 147(4):426-35. PubMed ID: 10672637
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Population pharmacokinetics, brain distribution, and pharmacodynamics of 2nd generation dopamine transporter selective benztropine analogs developed as potential substitute therapeutics for treatment of cocaine abuse.
    Syed SA; Newman AH; Othman AA; Eddington ND
    J Pharm Sci; 2008 May; 97(5):1993-2007. PubMed ID: 17879975
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of N-substituted analogs of benztropine: diminished cocaine-like effects in dopamine transporter ligands.
    Katz JL; Kopajtic TA; Agoston GE; Newman AH
    J Pharmacol Exp Ther; 2004 May; 309(2):650-60. PubMed ID: 14755006
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-{2-[bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and benztropine analogs.
    Desai RI; Kopajtic TA; French D; Newman AH; Katz JL
    J Pharmacol Exp Ther; 2005 Oct; 315(1):397-404. PubMed ID: 16014753
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Further studies of the reinforcing effects of benztropine analogs in rhesus monkeys.
    Woolverton WL; Hecht GS; Agoston GE; Katz JL; Newman AH
    Psychopharmacology (Berl); 2001 Apr; 154(4):375-82. PubMed ID: 11349390
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Place conditioning and locomotor effects of N-substituted, 4',4''-difluorobenztropine analogs in rats.
    Li SM; Newman AH; Katz JL
    J Pharmacol Exp Ther; 2005 Jun; 313(3):1223-30. PubMed ID: 15743929
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of drugs to treat cocaine dependence: behavioral and neurochemical effects of atypical dopamine transport inhibitors.
    Tanda G; Newman AH; Katz JL
    Adv Pharmacol; 2009; 57():253-89. PubMed ID: 20230764
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evaluation of the blood-brain barrier transport, population pharmacokinetics, and brain distribution of benztropine analogs and cocaine using in vitro and in vivo techniques.
    Raje S; Cao J; Newman AH; Gao H; Eddington ND
    J Pharmacol Exp Ther; 2003 Nov; 307(2):801-8. PubMed ID: 12966155
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Assessment of the influence of histaminergic actions on cocaine-like effects of 3alpha-diphenylmethoxytropane analogs.
    Campbell VC; Kopajtic TA; Newman AH; Katz JL
    J Pharmacol Exp Ther; 2005 Nov; 315(2):631-40. PubMed ID: 16055673
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine.
    Chen N; Zhen J; Reith ME
    J Neurochem; 2004 May; 89(4):853-64. PubMed ID: 15140185
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Therapeutic-like properties of a dopamine uptake inhibitor in animal models of amphetamine addiction.
    Velazquez-Sanchez C; Ferragud A; Renau-Piqueras J; Canales JJ
    Int J Neuropsychopharmacol; 2011 Jun; 14(5):655-65. PubMed ID: 20735880
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.