BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

444 related articles for article (PubMed ID: 17520061)

  • 1. Molecular mechanisms of the diabetogenic effects of arsenic: inhibition of insulin signaling by arsenite and methylarsonous acid.
    Paul DS; Harmon AW; Devesa V; Thomas DJ; Stýblo M
    Environ Health Perspect; 2007 May; 115(5):734-42. PubMed ID: 17520061
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of insulin-dependent glucose uptake by trivalent arsenicals: possible mechanism of arsenic-induced diabetes.
    Walton FS; Harmon AW; Paul DS; Drobná Z; Patel YM; Styblo M
    Toxicol Appl Pharmacol; 2004 Aug; 198(3):424-33. PubMed ID: 15276423
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of phosphoinositide metabolism, Akt phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes.
    Ono H; Katagiri H; Funaki M; Anai M; Inukai K; Fukushima Y; Sakoda H; Ogihara T; Onishi Y; Fujishiro M; Kikuchi M; Oka Y; Asano T
    Mol Endocrinol; 2001 Aug; 15(8):1411-22. PubMed ID: 11463863
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prolonged inorganic arsenite exposure suppresses insulin-stimulated AKT S473 phosphorylation and glucose uptake in 3T3-L1 adipocytes: involvement of the adaptive antioxidant response.
    Xue P; Hou Y; Zhang Q; Woods CG; Yarborough K; Liu H; Sun G; Andersen ME; Pi J
    Biochem Biophys Res Commun; 2011 Apr; 407(2):360-5. PubMed ID: 21396911
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical protein kinase C but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes.
    Egawa K; Maegawa H; Shi K; Nakamura T; Obata T; Yoshizaki T; Morino K; Shimizu S; Nishio Y; Suzuki E; Kashiwagi A
    J Biol Chem; 2002 Oct; 277(41):38863-9. PubMed ID: 12147684
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes.
    Tremblay F; Gagnon A; Veilleux A; Sorisky A; Marette A
    Endocrinology; 2005 Mar; 146(3):1328-37. PubMed ID: 15576463
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nelfinavir-induced insulin resistance is associated with impaired plasma membrane recruitment of the PI 3-kinase effectors Akt/PKB and PKC-zeta.
    Ben-Romano R; Rudich A; Tirosh A; Potashnik R; Sasaoka T; Riesenberg K; Schlaeffer F; Bashan N
    Diabetologia; 2004 Jun; 47(6):1107-17. PubMed ID: 15168016
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Loss of PTEN expression does not contribute to PDK-1 activity and PKC activation-loop phosphorylation in Jurkat leukaemic T cells.
    Freeley M; Park J; Yang KJ; Wange RL; Volkov Y; Kelleher D; Long A
    Cell Signal; 2007 Dec; 19(12):2444-57. PubMed ID: 17826953
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Postreceptoral adipocyte insulin resistance induced by nelfinavir is caused by insensitivity of PKB/Akt to phosphatidylinositol-3,4,5-trisphosphate.
    Kachko I; Maissel A; Mazor L; Ben-Romano R; Watson RT; Hou JC; Pessin JE; Bashan N; Rudich A
    Endocrinology; 2009 Jun; 150(6):2618-26. PubMed ID: 19179444
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Exposures to arsenite and methylarsonite produce insulin resistance and impair insulin-dependent glycogen metabolism in hepatocytes.
    Zhang C; Fennel EMJ; Douillet C; Stýblo M
    Arch Toxicol; 2017 Dec; 91(12):3811-3821. PubMed ID: 28952001
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes.
    Tang X; Powelka AM; Soriano NA; Czech MP; Guilherme A
    J Biol Chem; 2005 Jun; 280(23):22523-9. PubMed ID: 15824124
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Arsenite and its trivalent methylated metabolites inhibit glucose-stimulated calcium influx and insulin secretion in murine pancreatic islets.
    Huang M; Douillet C; Stýblo M
    Arch Toxicol; 2019 Sep; 93(9):2525-2533. PubMed ID: 31332465
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of PDK1 in insulin-signaling pathway for glucose metabolism in 3T3-L1 adipocytes.
    Yamada T; Katagiri H; Asano T; Tsuru M; Inukai K; Ono H; Kodama T; Kikuchi M; Oka Y
    Am J Physiol Endocrinol Metab; 2002 Jun; 282(6):E1385-94. PubMed ID: 12006370
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Requirement for 3-phosphoinositide-kependent dinase-1 (PDK-1) in insulin-induced glucose uptake in immortalized brown adipocytes.
    Sakaue H; Nishizawa A; Ogawa W; Teshigawara K; Mori T; Takashima Y; Noda T; Kasuga M
    J Biol Chem; 2003 Oct; 278(40):38870-4. PubMed ID: 12855688
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system A amino acid uptake.
    Green CJ; Göransson O; Kular GS; Leslie NR; Gray A; Alessi DR; Sakamoto K; Hundal HS
    J Biol Chem; 2008 Oct; 283(41):27653-27667. PubMed ID: 18669636
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The effects of intracellular calcium depletion on insulin signaling in 3T3-L1 adipocytes.
    Worrall DS; Olefsky JM
    Mol Endocrinol; 2002 Feb; 16(2):378-89. PubMed ID: 11818508
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells.
    Jiang ZY; Zhou QL; Holik J; Patel S; Leszyk J; Coleman K; Chouinard M; Czech MP
    J Biol Chem; 2005 Jun; 280(22):21622-8. PubMed ID: 15799971
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.
    Ugi S; Imamura T; Maegawa H; Egawa K; Yoshizaki T; Shi K; Obata T; Ebina Y; Kashiwagi A; Olefsky JM
    Mol Cell Biol; 2004 Oct; 24(19):8778-89. PubMed ID: 15367694
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Methylated trivalent arsenicals are potent inhibitors of glucose stimulated insulin secretion by murine pancreatic islets.
    Douillet C; Currier J; Saunders J; Bodnar WM; Matoušek T; Stýblo M
    Toxicol Appl Pharmacol; 2013 Feb; 267(1):11-5. PubMed ID: 23261974
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanism of inhibition of insulin-stimulated glucose transport by 4-bromocrotonic acid in 3T3-L1 adipocytes.
    Chai SP; Fong JC
    Cell Signal; 2003 Mar; 15(3):269-77. PubMed ID: 12531425
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.