347 related articles for article (PubMed ID: 17521388)
1. Werner syndrome protein prevents DNA breaks upon chromatin structure alteration.
Turaga RV; Massip L; Chavez A; Johnson FB; Lebel M
Aging Cell; 2007 Aug; 6(4):471-81. PubMed ID: 17521388
[TBL] [Abstract][Full Text] [Related]
2. WRN helicase defective in the premature aging disorder Werner syndrome genetically interacts with topoisomerase 3 and restores the top3 slow growth phenotype of sgs1 top3.
Aggarwal M; Brosh RM
Aging (Albany NY); 2009 Feb; 1(2):219-33. PubMed ID: 20157511
[TBL] [Abstract][Full Text] [Related]
3. Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice.
Lebel M; Lavoie J; Gaudreault I; Bronsard M; Drouin R
Am J Pathol; 2003 May; 162(5):1559-69. PubMed ID: 12707040
[TBL] [Abstract][Full Text] [Related]
4. Werner protein stimulates topoisomerase I DNA relaxation activity.
Laine JP; Opresko PL; Indig FE; Harrigan JA; von Kobbe C; Bohr VA
Cancer Res; 2003 Nov; 63(21):7136-46. PubMed ID: 14612507
[TBL] [Abstract][Full Text] [Related]
5. WRN protects against topo I but not topo II inhibitors by preventing DNA break formation.
Christmann M; Tomicic MT; Gestrich C; Roos WP; Bohr VA; Kaina B
DNA Repair (Amst); 2008 Dec; 7(12):1999-2009. PubMed ID: 18805512
[TBL] [Abstract][Full Text] [Related]
6. Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteins.
Machwe A; Lozada EM; Xiao L; Orren DK
BMC Mol Biol; 2006 Jan; 7():1. PubMed ID: 16412221
[TBL] [Abstract][Full Text] [Related]
7. Premature aging syndrome gene WRN genetically interacts with a topoisomerase.
Aggarwal M; Brosh RM
Cell Cycle; 2009 Jul; 8(14):2143. PubMed ID: 19587535
[No Abstract] [Full Text] [Related]
8. The Werner syndrome protein functions in repair of Cr(VI)-induced replication-associated DNA damage.
Liu FJ; Barchowsky A; Opresko PL
Toxicol Sci; 2009 Aug; 110(2):307-18. PubMed ID: 19487340
[TBL] [Abstract][Full Text] [Related]
9. WRN translocation from nucleolus to nucleoplasm is regulated by SIRT1 and required for DNA repair and the development of chemoresistance.
Lee SY; Lee H; Kim ES; Park S; Lee J; Ahn B
Mutat Res; 2015 Apr; 774():40-8. PubMed ID: 25801465
[TBL] [Abstract][Full Text] [Related]
10. Functional role of the Werner syndrome RecQ helicase in human fibroblasts.
Dhillon KK; Sidorova J; Saintigny Y; Poot M; Gollahon K; Rabinovitch PS; Monnat RJ
Aging Cell; 2007 Feb; 6(1):53-61. PubMed ID: 17266675
[TBL] [Abstract][Full Text] [Related]
11. Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer.
Agrelo R; Cheng WH; Setien F; Ropero S; Espada J; Fraga MF; Herranz M; Paz MF; Sanchez-Cespedes M; Artiga MJ; Guerrero D; Castells A; von Kobbe C; Bohr VA; Esteller M
Proc Natl Acad Sci U S A; 2006 Jun; 103(23):8822-7. PubMed ID: 16723399
[TBL] [Abstract][Full Text] [Related]
12. p53 modulates RPA-dependent and RPA-independent WRN helicase activity.
Sommers JA; Sharma S; Doherty KM; Karmakar P; Yang Q; Kenny MK; Harris CC; Brosh RM
Cancer Res; 2005 Feb; 65(4):1223-33. PubMed ID: 15735006
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress.
Aggarwal M; Sommers JA; Shoemaker RH; Brosh RM
Proc Natl Acad Sci U S A; 2011 Jan; 108(4):1525-30. PubMed ID: 21220316
[TBL] [Abstract][Full Text] [Related]
14. Werner protein protects nonproliferating cells from oxidative DNA damage.
Szekely AM; Bleichert F; Nümann A; Van Komen S; Manasanch E; Ben Nasr A; Canaan A; Weissman SM
Mol Cell Biol; 2005 Dec; 25(23):10492-506. PubMed ID: 16287861
[TBL] [Abstract][Full Text] [Related]
15. Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing.
Kusumoto R; Dawut L; Marchetti C; Wan Lee J; Vindigni A; Ramsden D; Bohr VA
Biochemistry; 2008 Jul; 47(28):7548-56. PubMed ID: 18558713
[TBL] [Abstract][Full Text] [Related]
16. WRN helicase regulates the ATR-CHK1-induced S-phase checkpoint pathway in response to topoisomerase-I-DNA covalent complexes.
Patro BS; Frøhlich R; Bohr VA; Stevnsner T
J Cell Sci; 2011 Dec; 124(Pt 23):3967-79. PubMed ID: 22159421
[TBL] [Abstract][Full Text] [Related]
17. The Werner syndrome helicase protein is required for cell proliferation, immortalization, and tumorigenesis in Scaffold attachment factor B1 deficient mice.
Lachapelle S; Oesterreich S; Lebel M
Aging (Albany NY); 2011 Mar; 3(3):277-90. PubMed ID: 21464516
[TBL] [Abstract][Full Text] [Related]
18. Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors.
Saydam N; Kanagaraj R; Dietschy T; Garcia PL; Peña-Diaz J; Shevelev I; Stagljar I; Janscak P
Nucleic Acids Res; 2007; 35(17):5706-16. PubMed ID: 17715146
[TBL] [Abstract][Full Text] [Related]
19. RECQL5 plays co-operative and complementary roles with WRN syndrome helicase.
Popuri V; Huang J; Ramamoorthy M; Tadokoro T; Croteau DL; Bohr VA
Nucleic Acids Res; 2013 Jan; 41(2):881-99. PubMed ID: 23180761
[TBL] [Abstract][Full Text] [Related]
20. Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice.
Yamamoto ML; Reliene R; Oshima J; Schiestl RH
Mutat Res; 2008 Sep; 644(1-2):11-6. PubMed ID: 18639560
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]