175 related articles for article (PubMed ID: 17524981)
1. Design, synthesis, and evaluation of in vivo potency and selectivity of epoxysuccinyl-based inhibitors of papain-family cysteine proteases.
Sadaghiani AM; Verhelst SH; Gocheva V; Hill K; Majerova E; Stinson S; Joyce JA; Bogyo M
Chem Biol; 2007 May; 14(5):499-511. PubMed ID: 17524981
[TBL] [Abstract][Full Text] [Related]
2. Mechanistic studies on the inactivation of papain by epoxysuccinyl inhibitors.
Meara JP; Rich DH
J Med Chem; 1996 Aug; 39(17):3357-66. PubMed ID: 8765519
[TBL] [Abstract][Full Text] [Related]
3. Design of potent, selective, and orally bioavailable inhibitors of cysteine protease cathepsin k.
Tavares FX; Boncek V; Deaton DN; Hassell AM; Long ST; Miller AB; Payne AA; Miller LR; Shewchuk LM; Wells-Knecht K; Willard DH; Wright LL; Zhou HQ
J Med Chem; 2004 Jan; 47(3):588-99. PubMed ID: 14736240
[TBL] [Abstract][Full Text] [Related]
4. Novel aza peptide inhibitors and active-site probes of papain-family cysteine proteases.
Verhelst SH; Witte MD; Arastu-Kapur S; Fonovic M; Bogyo M
Chembiochem; 2006 Jun; 7(6):943-50. PubMed ID: 16607671
[TBL] [Abstract][Full Text] [Related]
5. 3,4-disubstituted azetidinones as selective inhibitors of the cysteine protease cathepsin K. Exploring P3 elements for potency and selectivity.
Setti EL; Davis D; Janc JW; Jeffery DA; Cheung H; Yu W
Bioorg Med Chem Lett; 2005 Mar; 15(5):1529-34. PubMed ID: 15713422
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of cysteine proteases by peptides containing aziridine-2,3-dicarboxylic acid building blocks.
Schirmeister T
Biopolymers; 1999; 51(1):87-97. PubMed ID: 10380356
[TBL] [Abstract][Full Text] [Related]
7. Binding modes of a new epoxysuccinyl-peptide inhibitor of cysteine proteases. Where and how do cysteine proteases express their selectivity?
Czaplewski C; Grzonka Z; Jaskólski M; Kasprzykowski F; Kozak M; Politowska E; Ciarkowski J
Biochim Biophys Acta; 1999 May; 1431(2):290-305. PubMed ID: 10350606
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and evaluation of chloromethyl sulfoxides as a new class of selective irreversible cysteine protease inhibitors.
Brouwer AJ; Bunschoten A; Liskamp RM
Bioorg Med Chem; 2007 Nov; 15(22):6985-93. PubMed ID: 17869119
[TBL] [Abstract][Full Text] [Related]
9. Inactivation of cysteine proteases by peptidyl epoxides: characterization of the alkylation sites on the enzyme and the inactivator.
Albeck A; Kliper S
Biochem J; 2000 Feb; 346 Pt 1(Pt 1):71-6. PubMed ID: 10657241
[TBL] [Abstract][Full Text] [Related]
10. Development of cell-active non-peptidyl inhibitors of cysteine cathepsins.
Dana D; Davalos AR; De S; Rathod P; Gamage RK; Huestis J; Afzal N; Zavlanov Y; Paroly SS; Rotenberg SA; Subramaniam G; Mark KJ; Chang EJ; Kumar S
Bioorg Med Chem; 2013 Jun; 21(11):2975-87. PubMed ID: 23623677
[TBL] [Abstract][Full Text] [Related]
11. Syntheses and SH-enzyme inhibitory activities of new epoxysuccinic acid piperazine derivatives against mu-calpain and cathepsin B.
Inoue J; Yoshida Y; Nakamura M; Cui YS; Nagao Y
Drug Des Discov; 1999 Aug; 16(2):165-9. PubMed ID: 10533812
[TBL] [Abstract][Full Text] [Related]
12. Screening for selective small molecule inhibitors of the proteasome using activity-based probes.
Bogyo M
Methods Enzymol; 2005; 399():609-22. PubMed ID: 16338384
[TBL] [Abstract][Full Text] [Related]
13. 4-Amino-2-cyanopyrimidines: novel scaffold for nonpeptidic cathepsin S inhibitors.
Irie O; Yokokawa F; Ehara T; Iwasaki A; Iwaki Y; Hitomi Y; Konishi K; Kishida M; Toyao A; Masuya K; Gunji H; Sakaki J; Iwasaki G; Hirao H; Kanazawa T; Tanabe K; Kosaka T; Hart TW; Hallett A
Bioorg Med Chem Lett; 2008 Aug; 18(16):4642-6. PubMed ID: 18662880
[TBL] [Abstract][Full Text] [Related]
14. Design, Synthesis, and Structure-Activity Relationship Study of Epoxysuccinyl-Peptide Derivatives as Cathepsin B Inhibitors.
Zhang X; Yang X; Wang H; Li S; Guo K; Jiang D; Xiao J; Liang D
Biol Pharm Bull; 2017 Aug; 40(8):1240-1246. PubMed ID: 28502922
[TBL] [Abstract][Full Text] [Related]
15. Solid-phase synthesis of double-headed epoxysuccinyl activity-based probes for selective targeting of papain family cysteine proteases.
Verhelst SH; Bogyo M
Chembiochem; 2005 May; 6(5):824-7. PubMed ID: 15776409
[No Abstract] [Full Text] [Related]
16. Azadipeptide nitriles: highly potent and proteolytically stable inhibitors of papain-like cysteine proteases.
Löser R; Frizler M; Schilling K; Gütschow M
Angew Chem Int Ed Engl; 2008; 47(23):4331-4. PubMed ID: 18404765
[No Abstract] [Full Text] [Related]
17. Peptidyl epoxides extended in the P' direction as cysteine protease inhibitors: effect on affinity and mechanism of inhibition.
Perlman N; Hazan M; Shokhen M; Albeck A
Bioorg Med Chem; 2008 Oct; 16(19):9032-9. PubMed ID: 18789705
[TBL] [Abstract][Full Text] [Related]
18. Theoretical studies of binding modes of two covalent inhibitors of cysteine proteases.
Drabik P; Politowska E; Czaplewski C; Kasprzykowski F; Lankiewicz L; Ciarkowski J
Acta Biochim Pol; 2000; 47(4):1061-6. PubMed ID: 11996096
[TBL] [Abstract][Full Text] [Related]
19. Aza-peptide epoxides: a new class of inhibitors selective for clan CD cysteine proteases.
Asgian JL; James KE; Li ZZ; Carter W; Barrett AJ; Mikolajczyk J; Salvesen GS; Powers JC
J Med Chem; 2002 Nov; 45(23):4958-60. PubMed ID: 12408706
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis, and evaluation of aza-peptide epoxides as selective and potent inhibitors of caspases-1, -3, -6, and -8.
James KE; Asgian JL; Li ZZ; Ekici OD; Rubin JR; Mikolajczyk J; Salvesen GS; Powers JC
J Med Chem; 2004 Mar; 47(6):1553-74. PubMed ID: 14998341
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
