343 related articles for article (PubMed ID: 17526493)
1. The Mre11-Rad50-Nbs1 complex acts both upstream and downstream of ataxia telangiectasia mutated and Rad3-related protein (ATR) to regulate the S-phase checkpoint following UV treatment.
Olson E; Nievera CJ; Lee AY; Chen L; Wu X
J Biol Chem; 2007 Aug; 282(31):22939-52. PubMed ID: 17526493
[TBL] [Abstract][Full Text] [Related]
2. Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
Takemura H; Rao VA; Sordet O; Furuta T; Miao ZH; Meng L; Zhang H; Pommier Y
J Biol Chem; 2006 Oct; 281(41):30814-23. PubMed ID: 16905549
[TBL] [Abstract][Full Text] [Related]
3. The Mre11/Rad50/Nbs1 complex plays an important role in the prevention of DNA rereplication in mammalian cells.
Lee AY; Liu E; Wu X
J Biol Chem; 2007 Nov; 282(44):32243-55. PubMed ID: 17715134
[TBL] [Abstract][Full Text] [Related]
4. RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint.
Olson E; Nievera CJ; Klimovich V; Fanning E; Wu X
J Biol Chem; 2006 Dec; 281(51):39517-33. PubMed ID: 17035231
[TBL] [Abstract][Full Text] [Related]
5. Functional analysis of FHA and BRCT domains of NBS1 in chromatin association and DNA damage responses.
Zhao S; Renthal W; Lee EY
Nucleic Acids Res; 2002 Nov; 30(22):4815-22. PubMed ID: 12433983
[TBL] [Abstract][Full Text] [Related]
6. Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm.
Cerosaletti K; Concannon P
J Biol Chem; 2004 Sep; 279(37):38813-9. PubMed ID: 15234984
[TBL] [Abstract][Full Text] [Related]
7. ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance.
Ewald B; Sampath D; Plunkett W
Cancer Res; 2008 Oct; 68(19):7947-55. PubMed ID: 18829552
[TBL] [Abstract][Full Text] [Related]
8. Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks.
Robison JG; Elliott J; Dixon K; Oakley GG
J Biol Chem; 2004 Aug; 279(33):34802-10. PubMed ID: 15180989
[TBL] [Abstract][Full Text] [Related]
9. Requirement for NBS1 in the S phase checkpoint response to DNA methylation combined with PARP inhibition.
Horton JK; Stefanick DF; Zeng JY; Carrozza MJ; Wilson SH
DNA Repair (Amst); 2011 Feb; 10(2):225-34. PubMed ID: 21130714
[TBL] [Abstract][Full Text] [Related]
10. Rad50 depletion impacts upon ATR-dependent DNA damage responses.
Zhong H; Bryson A; Eckersdorff M; Ferguson DO
Hum Mol Genet; 2005 Sep; 14(18):2685-93. PubMed ID: 16087684
[TBL] [Abstract][Full Text] [Related]
11. Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.
Lee JH; Mand MR; Deshpande RA; Kinoshita E; Yang SH; Wyman C; Paull TT
J Biol Chem; 2013 May; 288(18):12840-51. PubMed ID: 23525106
[TBL] [Abstract][Full Text] [Related]
12. Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.
Gatei M; Sloper K; Sorensen C; Syljuäsen R; Falck J; Hobson K; Savage K; Lukas J; Zhou BB; Bartek J; Khanna KK
J Biol Chem; 2003 Apr; 278(17):14806-11. PubMed ID: 12588868
[TBL] [Abstract][Full Text] [Related]
13. Mystery of DNA repair: the role of the MRN complex and ATM kinase in DNA damage repair.
Czornak K; Chughtai S; Chrzanowska KH
J Appl Genet; 2008; 49(4):383-96. PubMed ID: 19029686
[TBL] [Abstract][Full Text] [Related]
14. Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage.
Lee JH; Xu B; Lee CH; Ahn JY; Song MS; Lee H; Canman CE; Lee JS; Kastan MB; Lim DS
Mol Cancer Res; 2003 Jul; 1(9):674-81. PubMed ID: 12861053
[TBL] [Abstract][Full Text] [Related]
15. Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection.
Shirata N; Kudoh A; Daikoku T; Tatsumi Y; Fujita M; Kiyono T; Sugaya Y; Isomura H; Ishizaki K; Tsurumi T
J Biol Chem; 2005 Aug; 280(34):30336-41. PubMed ID: 15964848
[TBL] [Abstract][Full Text] [Related]
16. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
Williams RS; Williams JS; Tainer JA
Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
[TBL] [Abstract][Full Text] [Related]
17. Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection.
Carson CT; Orazio NI; Lee DV; Suh J; Bekker-Jensen S; Araujo FD; Lakdawala SS; Lilley CE; Bartek J; Lukas J; Weitzman MD
EMBO J; 2009 Mar; 28(6):652-62. PubMed ID: 19197236
[TBL] [Abstract][Full Text] [Related]
18. Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis.
Taylor AM; Groom A; Byrd PJ
DNA Repair (Amst); 2004; 3(8-9):1219-25. PubMed ID: 15279810
[TBL] [Abstract][Full Text] [Related]
19. The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM.
Yoo HY; Kumagai A; Shevchenko A; Shevchenko A; Dunphy WG
Mol Biol Cell; 2009 May; 20(9):2351-60. PubMed ID: 19279141
[TBL] [Abstract][Full Text] [Related]
20. The role of NBS1 in the modulation of PIKK family proteins ATM and ATR in the cellular response to DNA damage.
Zhou J; Lim CU; Li JJ; Cai L; Zhang Y
Cancer Lett; 2006 Nov; 243(1):9-15. PubMed ID: 16530324
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]