These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

466 related articles for article (PubMed ID: 17542811)

  • 41. Mechanism of gamma-secretase cleavage activation: is gamma-secretase regulated through autoinhibition involving the presenilin-1 exon 9 loop?
    Knappenberger KS; Tian G; Ye X; Sobotka-Briner C; Ghanekar SV; Greenberg BD; Scott CW
    Biochemistry; 2004 May; 43(20):6208-18. PubMed ID: 15147205
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Mutations in APP have independent effects on Abeta and CTFgamma generation.
    Hecimovic S; Wang J; Dolios G; Martinez M; Wang R; Goate AM
    Neurobiol Dis; 2004 Nov; 17(2):205-18. PubMed ID: 15474359
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Secretase inhibitors for Alzheimer's disease: challenges of a promiscuous protease.
    Pollack SJ; Lewis H
    Curr Opin Investig Drugs; 2005 Jan; 6(1):35-47. PubMed ID: 15675602
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) as a biological candidate marker of Alzheimer's disease.
    Hampel H; Shen Y
    Scand J Clin Lab Invest; 2009; 69(1):8-12. PubMed ID: 18609117
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Effects of huperzine A on amyloid precursor protein processing and beta-amyloid generation in human embryonic kidney 293 APP Swedish mutant cells.
    Peng Y; Jiang L; Lee DY; Schachter SC; Ma Z; Lemere CA
    J Neurosci Res; 2006 Sep; 84(4):903-11. PubMed ID: 16862548
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.
    Sevalle J; Ayral E; Hernandez JF; Martinez J; Checler F
    J Neurochem; 2009 Jul; 110(1):275-83. PubMed ID: 19457123
    [TBL] [Abstract][Full Text] [Related]  

  • 47. The role of low-density receptor-related protein 1 (LRP1) as a competitive substrate of the amyloid precursor protein (APP) for BACE1.
    von Einem B; Schwanzar D; Rehn F; Beyer AS; Weber P; Wagner M; Schneckenburger H; von Arnim CA
    Exp Neurol; 2010 Sep; 225(1):85-93. PubMed ID: 20685197
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Dynamics of Abeta turnover and deposition in different beta-amyloid precursor protein transgenic mouse models following gamma-secretase inhibition.
    Abramowski D; Wiederhold KH; Furrer U; Jaton AL; Neuenschwander A; Runser MJ; Danner S; Reichwald J; Ammaturo D; Staab D; Stoeckli M; Rueeger H; Neumann U; Staufenbiel M
    J Pharmacol Exp Ther; 2008 Nov; 327(2):411-24. PubMed ID: 18687920
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Etazolate, a neuroprotective drug linking GABA(A) receptor pharmacology to amyloid precursor protein processing.
    Marcade M; Bourdin J; Loiseau N; Peillon H; Rayer A; Drouin D; Schweighoffer F; Désiré L
    J Neurochem; 2008 Jul; 106(1):392-404. PubMed ID: 18397369
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Effects of galantamine on β-amyloid release and beta-site cleaving enzyme 1 expression in differentiated human neuroblastoma SH-SY5Y cells.
    Li Q; Wu D; Zhang L; Zhang Y
    Exp Gerontol; 2010 Nov; 45(11):842-7. PubMed ID: 20600777
    [TBL] [Abstract][Full Text] [Related]  

  • 51. LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.
    Majercak J; Ray WJ; Espeseth A; Simon A; Shi XP; Wolffe C; Getty K; Marine S; Stec E; Ferrer M; Strulovici B; Bartz S; Gates A; Xu M; Huang Q; Ma L; Shughrue P; Burchard J; Colussi D; Pietrak B; Kahana J; Beher D; Rosahl T; Shearman M; Hazuda D; Sachs AB; Koblan KS; Seabrook GR; Stone DJ
    Proc Natl Acad Sci U S A; 2006 Nov; 103(47):17967-72. PubMed ID: 17098871
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Is BACE1 a suitable therapeutic target for the treatment of Alzheimer's disease? Current strategies and future directions.
    Klaver DW; Wilce MC; Cui H; Hung AC; Gasperini R; Foa L; Small DH
    Biol Chem; 2010 Aug; 391(8):849-59. PubMed ID: 20731541
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Cholesterol-like effects of selective cyclooxygenase inhibitors and fibrates on cellular membranes and amyloid-beta production.
    Gamerdinger M; Clement AB; Behl C
    Mol Pharmacol; 2007 Jul; 72(1):141-51. PubMed ID: 17395689
    [TBL] [Abstract][Full Text] [Related]  

  • 54. S-Adenosylhomocysteine increases beta-amyloid formation in BV-2 microglial cells by increased expressions of beta-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters.
    Lin HC; Hsieh HM; Chen YH; Hu ML
    Neurotoxicology; 2009 Jul; 30(4):622-7. PubMed ID: 19635394
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for beta-amyloid peptide over-production and localization in Alzheimer's disease.
    Yu WH; Kumar A; Peterhoff C; Shapiro Kulnane L; Uchiyama Y; Lamb BT; Cuervo AM; Nixon RA
    Int J Biochem Cell Biol; 2004 Dec; 36(12):2531-40. PubMed ID: 15325590
    [TBL] [Abstract][Full Text] [Related]  

  • 56. 2,2',4'-trihydroxychalcone from Glycyrrhiza glabra as a new specific BACE1 inhibitor efficiently ameliorates memory impairment in mice.
    Zhu Z; Li C; Wang X; Yang Z; Chen J; Hu L; Jiang H; Shen X
    J Neurochem; 2010 Jul; 114(2):374-85. PubMed ID: 20412384
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Inhibition of gamma-secretase activity by helical beta-peptide foldamers.
    Imamura Y; Watanabe N; Umezawa N; Iwatsubo T; Kato N; Tomita T; Higuchi T
    J Am Chem Soc; 2009 Jun; 131(21):7353-9. PubMed ID: 19432477
    [TBL] [Abstract][Full Text] [Related]  

  • 58. A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo.
    Atwal JK; Chen Y; Chiu C; Mortensen DL; Meilandt WJ; Liu Y; Heise CE; Hoyte K; Luk W; Lu Y; Peng K; Wu P; Rouge L; Zhang Y; Lazarus RA; Scearce-Levie K; Wang W; Wu Y; Tessier-Lavigne M; Watts RJ
    Sci Transl Med; 2011 May; 3(84):84ra43. PubMed ID: 21613622
    [TBL] [Abstract][Full Text] [Related]  

  • 59. BACE inhibitor reduces APP-beta-C-terminal fragment accumulation in axonal swellings of okadaic acid-induced neurodegeneration.
    Yoon SY; Choi JE; Yoon JH; Huh JW; Kim DH
    Neurobiol Dis; 2006 May; 22(2):435-44. PubMed ID: 16480887
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Secretion of long Abeta-related peptides processed at epsilon-cleavage site is dependent on the alpha-secretase pre-cutting.
    Kametani F
    FEBS Lett; 2004 Jul; 570(1-3):73-6. PubMed ID: 15251442
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 24.