186 related articles for article (PubMed ID: 17546464)
1. Mitochondrial disruption and DNA fragmentation in Trypanosoma cruzi induced by naphthoimidazoles synthesized from beta-lapachone.
Menna-Barreto RF; Corrêa JR; Pinto AV; Soares MJ; de Castro SL
Parasitol Res; 2007 Sep; 101(4):895-905. PubMed ID: 17546464
[TBL] [Abstract][Full Text] [Related]
2. Naphthoimidazoles promote different death phenotypes in Trypanosoma cruzi.
Menna-Barreto RF; Corrêa JR; Cascabulho CM; Fernandes MC; Pinto AV; Soares MJ; De Castro SL
Parasitology; 2009 Apr; 136(5):499-510. PubMed ID: 19281638
[TBL] [Abstract][Full Text] [Related]
3. Mitochondrial disfunction and ROS production are essential for anti-Trypanosoma cruzi activity of β-lapachone-derived naphthoimidazoles.
Bombaça ACS; Viana PG; Santos ACC; Silva TL; Rodrigues ABM; Guimarães ACR; Goulart MOF; da Silva Júnior EN; Menna-Barreto RFS
Free Radic Biol Med; 2019 Jan; 130():408-418. PubMed ID: 30445126
[TBL] [Abstract][Full Text] [Related]
4. Effect of a beta-lapachone-derived naphthoimidazole on Trypanosoma cruzi: identification of target organelles.
Menna-Barreto RF; Henriques-Pons A; Pinto AV; Morgado-Diaz JA; Soares MJ; De Castro SL
J Antimicrob Chemother; 2005 Dec; 56(6):1034-41. PubMed ID: 16269551
[TBL] [Abstract][Full Text] [Related]
5. The effects on Trypanosoma cruzi of novel synthetic naphthoquinones are mediated by mitochondrial dysfunction.
Menna-Barreto RF; Goncalves RL; Costa EM; Silva RS; Pinto AV; Oliveira MF; de Castro SL
Free Radic Biol Med; 2009 Sep; 47(5):644-53. PubMed ID: 19501647
[TBL] [Abstract][Full Text] [Related]
6. Novel N,N-di-alkylnaphthoimidazolium derivative of β-lapachone impaired Trypanosoma cruzi mitochondrial electron transport system.
Bombaça ACS; Silva LA; Chaves OA; da Silva LS; Barbosa JMC; da Silva AM; Ferreira ABB; Menna-Barreto RFS
Biomed Pharmacother; 2021 Mar; 135():111186. PubMed ID: 33395606
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological activity against Trypanosoma cruzi of substituted 1,4-naphthoquinones.
Olímpio da Silva A; da Silva Lopes R; Vieira de Lima R; Santos Suniga Tozatti C; Marques MR; de Albuquerque S; Beatriz A; Pires de Lima D
Eur J Med Chem; 2013 Feb; 60():51-6. PubMed ID: 23279867
[TBL] [Abstract][Full Text] [Related]
8. Trypanosoma cruzi: ultrastructural and metabolic alterations of epimastigotes by beta-lapachone.
Docampo R; Lopes JN; Cruz FS; Souza W
Exp Parasitol; 1977 Jun; 42(1):142-9. PubMed ID: 324785
[No Abstract] [Full Text] [Related]
9. Synthesis and anti-Trypanosoma cruzi activity of derivatives from nor-lapachones and lapachones.
da Silva Júnior EN; de Souza MC; Fernandes MC; Menna-Barreto RF; Pinto Mdo C; de Assis Lopes F; de Simone CA; Andrade CK; Pinto AV; Ferreira VF; de Castro SL
Bioorg Med Chem; 2008 May; 16(9):5030-8. PubMed ID: 18378461
[TBL] [Abstract][Full Text] [Related]
10. Different cell death pathways induced by drugs in Trypanosoma cruzi: an ultrastructural study.
Menna-Barreto RF; Salomão K; Dantas AP; Santa-Rita RM; Soares MJ; Barbosa HS; de Castro SL
Micron; 2009 Feb; 40(2):157-68. PubMed ID: 18849169
[TBL] [Abstract][Full Text] [Related]
11. Effect of L-leucine methyl ester on growth and ultrastructure of Trypanosoma cruzi.
Adade CM; Figueiredo RC; De Castro SL; Soares MJ
Acta Trop; 2007 Jan; 101(1):69-79. PubMed ID: 17250794
[TBL] [Abstract][Full Text] [Related]
12. A proteomic analysis of the mechanism of action of naphthoimidazoles in Trypanosoma cruzi epimastigotes in vitro.
Menna-Barreto RF; Beghini DG; Ferreira AT; Pinto AV; De Castro SL; Perales J
J Proteomics; 2010 Nov; 73(12):2306-15. PubMed ID: 20621210
[TBL] [Abstract][Full Text] [Related]
13. A novel triazolic naphthofuranquinone induces autophagy in reservosomes and impairment of mitosis in Trypanosoma cruzi.
Fernandes MC; Da Silva EN; Pinto AV; De Castro SL; Menna-Barreto RF
Parasitology; 2012 Jan; 139(1):26-36. PubMed ID: 21939585
[TBL] [Abstract][Full Text] [Related]
14. In vitro activities of adamantylidene-substituted alkylphosphocholine TCAN26 against Trypanosoma cruzi: Antiproliferative and ultrastructural effects.
Barrias E; Reignault LC; Calogeropoulou T; de Souza W
Exp Parasitol; 2019 Nov; 206():107730. PubMed ID: 31494215
[TBL] [Abstract][Full Text] [Related]
15. Effects of a novel β-lapachone derivative on Trypanosoma cruzi: Parasite death involving apoptosis, autophagy and necrosis.
Dos Anjos DO; Sobral Alves ES; Gonçalves VT; Fontes SS; Nogueira ML; Suarez-Fontes AM; Neves da Costa JB; Rios-Santos F; Vannier-Santos MA
Int J Parasitol Drugs Drug Resist; 2016 Dec; 6(3):207-219. PubMed ID: 27770751
[TBL] [Abstract][Full Text] [Related]
16. Ultrastructural alterations and peroxide formation induced by naphthoquinones in different stages of Trypanosoma cruzi.
Docampo R; De Souza W; Cruz FS; Roitman I; Cover B; Gutteridge WE
Z Parasitenkd; 1978 Nov; 57(3):189-98. PubMed ID: 216177
[TBL] [Abstract][Full Text] [Related]
17. The evaluation of quinonoid compounds against Trypanosoma cruzi: synthesis of imidazolic anthraquinones, nor-beta-lapachone derivatives and beta-lapachone-based 1,2,3-triazoles.
da Silva EN; Guimarães TT; Menna-Barreto RF; Pinto Mdo C; de Simone CA; Pessoa C; Cavalcanti BC; Sabino JR; Andrade CK; Goulart MO; de Castro SL; Pinto AV
Bioorg Med Chem; 2010 May; 18(9):3224-30. PubMed ID: 20378360
[TBL] [Abstract][Full Text] [Related]
18. Studies on the trypanocidal activity of semi-synthetic pyran[b-4,3]naphtho[1,2-d]imidazoles from beta-lapachone.
De Moura KC; Salomão K; Menna-Barreto RF; Emery FS; Pinto Mdo C; Pinto AV; de Castro SL
Eur J Med Chem; 2004 Jul; 39(7):639-45. PubMed ID: 15236845
[TBL] [Abstract][Full Text] [Related]
19. Parallel synthesis of a library of 1,4-naphthoquinones and automated screening of potential inhibitors of trypanothione reductase from Trypanosoma cruzi.
Salmon-Chemin L; Lemaire A; De Freitas S; Deprez B; Sergheraert C; Davioud-Charvet E
Bioorg Med Chem Lett; 2000 Apr; 10(7):631-5. PubMed ID: 10762041
[TBL] [Abstract][Full Text] [Related]
20. Trypanosoma cruzi mitochondrial swelling and membrane potential collapse as primary evidence of the mode of action of naphthoquinone analogues.
Salomão K; De Santana NA; Molina MT; De Castro SL; Menna-Barreto RF
BMC Microbiol; 2013 Sep; 13():196. PubMed ID: 24004461
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
