BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

418 related articles for article (PubMed ID: 17554858)

  • 1. Molecular optimization using computational multi-objective methods.
    Nicolaou CA; Brown N; Pattichis CS
    Curr Opin Drug Discov Devel; 2007 May; 10(3):316-24. PubMed ID: 17554858
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Informatics and modeling challenges in fragment-based drug discovery.
    Hubbard RE; Chen I; Davis B
    Curr Opin Drug Discov Devel; 2007 May; 10(3):289-97. PubMed ID: 17554855
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lead optimization via high-throughput molecular docking.
    Joseph-McCarthy D; Baber JC; Feyfant E; Thompson DC; Humblet C
    Curr Opin Drug Discov Devel; 2007 May; 10(3):264-74. PubMed ID: 17554852
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ranking poses in structure-based lead discovery and optimization: current trends in scoring function development.
    Rajamani R; Good AC
    Curr Opin Drug Discov Devel; 2007 May; 10(3):308-15. PubMed ID: 17554857
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular modeling of hydration in drug design.
    Mancera RL
    Curr Opin Drug Discov Devel; 2007 May; 10(3):275-80. PubMed ID: 17554853
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Importance of molecular computer modeling in anticancer drug development.
    Geromichalos GD
    J BUON; 2007 Sep; 12 Suppl 1():S101-18. PubMed ID: 17935268
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In silico identification of bioisosteric functional groups.
    Ertl P
    Curr Opin Drug Discov Devel; 2007 May; 10(3):281-8. PubMed ID: 17554854
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Desirability-based methods of multiobjective optimization and ranking for global QSAR studies. Filtering safe and potent drug candidates from combinatorial libraries.
    Cruz-Monteagudo M; Borges F; Cordeiro MN; Cagide Fajin JL; Morell C; Ruiz RM; Cañizares-Carmenate Y; Dominguez ER
    J Comb Chem; 2008; 10(6):897-913. PubMed ID: 18855460
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Strategies of multi-objective optimization in drug discovery and development.
    Nicolotti O; Giangreco I; Introcaso A; Leonetti F; Stefanachi A; Carotti A
    Expert Opin Drug Discov; 2011 Sep; 6(9):871-84. PubMed ID: 22646211
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Physics-based methods for studying protein-ligand interactions.
    Huang N; Jacobson MP
    Curr Opin Drug Discov Devel; 2007 May; 10(3):325-31. PubMed ID: 17554859
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pocket extraction on proteins via the Voronoi diagram of spheres.
    Kim D; Cho CH; Cho Y; Ryu J; Bhak J; Kim DS
    J Mol Graph Model; 2008 Apr; 26(7):1104-12. PubMed ID: 18023220
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Basic overview of chemoinformatics.
    Engel T
    J Chem Inf Model; 2006; 46(6):2267-77. PubMed ID: 17125169
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The use of protein-ligand interaction fingerprints in docking.
    Brewerton SC
    Curr Opin Drug Discov Devel; 2008 May; 11(3):356-64. PubMed ID: 18428089
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Virtual high-throughput screening of molecular databases.
    Seifert MH; Kraus J; Kramer B
    Curr Opin Drug Discov Devel; 2007 May; 10(3):298-307. PubMed ID: 17554856
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Recent trends in library design: 'rational design' revisited.
    Schnur DM
    Curr Opin Drug Discov Devel; 2008 May; 11(3):375-80. PubMed ID: 18428091
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pareto optimization in computational protein design with multiple objectives.
    Suárez M; Tortosa P; Carrera J; Jaramillo A
    J Comput Chem; 2008 Dec; 29(16):2704-11. PubMed ID: 18496793
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-based drug metabolism predictions for drug design.
    Sun H; Scott DO
    Chem Biol Drug Des; 2010 Jan; 75(1):3-17. PubMed ID: 19878193
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthetic library design.
    Huwe CM
    Drug Discov Today; 2006 Aug; 11(15-16):763-7. PubMed ID: 16846805
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Designing a new Diels-Alderase: a combinatorial, semirational approach including dynamic optimization.
    Linder M; Johansson AJ; Olsson TS; Liebeschuetz J; Brinck T
    J Chem Inf Model; 2011 Aug; 51(8):1906-17. PubMed ID: 21780795
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Conformational sampling of bioactive molecules: a comparative study.
    Agrafiotis DK; Gibbs AC; Zhu F; Izrailev S; Martin E
    J Chem Inf Model; 2007; 47(3):1067-86. PubMed ID: 17411028
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.