These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 17556371)

  • 1. Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex.
    Sbrissa D; Ikonomov OC; Fu Z; Ijuin T; Gruenberg J; Takenawa T; Shisheva A
    J Biol Chem; 2007 Aug; 282(33):23878-91. PubMed ID: 17556371
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PIKfyve-ArPIKfyve-Sac3 core complex: contact sites and their consequence for Sac3 phosphatase activity and endocytic membrane homeostasis.
    Ikonomov OC; Sbrissa D; Fenner H; Shisheva A
    J Biol Chem; 2009 Dec; 284(51):35794-806. PubMed ID: 19840946
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ArPIKfyve regulates Sac3 protein abundance and turnover: disruption of the mechanism by Sac3I41T mutation causing Charcot-Marie-Tooth 4J disorder.
    Ikonomov OC; Sbrissa D; Fligger J; Delvecchio K; Shisheva A
    J Biol Chem; 2010 Aug; 285(35):26760-26764. PubMed ID: 20630877
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The PIKfyve-ArPIKfyve-Sac3 triad in human breast cancer: Functional link between elevated Sac3 phosphatase and enhanced proliferation of triple negative cell lines.
    Ikonomov OC; Filios C; Sbrissa D; Chen X; Shisheva A
    Biochem Biophys Res Commun; 2013 Oct; 440(2):342-7. PubMed ID: 24070605
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Protein Complex of Neurodegeneration-related Phosphoinositide Phosphatase Sac3 and ArPIKfyve Binds the Lewy Body-associated Synphilin-1, Preventing Its Aggregation.
    Ikonomov OC; Sbrissa D; Compton LM; Kumar R; Tisdale EJ; Chen X; Shisheva A
    J Biol Chem; 2015 Nov; 290(47):28515-28529. PubMed ID: 26405034
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionality.
    Sbrissa D; Ikonomov OC; Fenner H; Shisheva A
    J Mol Biol; 2008 Dec; 384(4):766-79. PubMed ID: 18950639
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Vac14 protein multimerization is a prerequisite step for Fab1 protein complex assembly and function.
    Alghamdi TA; Ho CY; Mrakovic A; Taylor D; Mao D; Botelho RJ
    J Biol Chem; 2013 Mar; 288(13):9363-72. PubMed ID: 23389034
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ArPIKfyve-PIKfyve interaction and role in insulin-regulated GLUT4 translocation and glucose transport in 3T3-L1 adipocytes.
    Ikonomov OC; Sbrissa D; Dondapati R; Shisheva A
    Exp Cell Res; 2007 Jul; 313(11):2404-16. PubMed ID: 17475247
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytes.
    Ikonomov OC; Sbrissa D; Ijuin T; Takenawa T; Shisheva A
    J Biol Chem; 2009 Sep; 284(36):23961-71. PubMed ID: 19578118
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase.
    Rudge SA; Anderson DM; Emr SD
    Mol Biol Cell; 2004 Jan; 15(1):24-36. PubMed ID: 14528018
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphatidylinositol (3,5)-bisphosphate machinery regulates neurite thickness through neuron-specific endosomal protein NSG1/NEEP21.
    Qi L; Sun C; Sun S; Li A; Hu Q; Liu Y; Zhang Y
    J Biol Chem; 2023 Jan; 299(1):102775. PubMed ID: 36493904
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The vacuolar morphology protein VAC14 plays an important role in sexual development in the filamentous ascomycete Sordaria macrospora.
    Groth A; Ahlmann S; Werner A; Pöggeler S
    Curr Genet; 2022 Aug; 68(3-4):407-427. PubMed ID: 35776170
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Localized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusion.
    Ikonomov OC; Sbrissa D; Shisheva A
    Am J Physiol Cell Physiol; 2006 Aug; 291(2):C393-404. PubMed ID: 16510848
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency.
    Compton LM; Ikonomov OC; Sbrissa D; Garg P; Shisheva A
    Am J Physiol Cell Physiol; 2016 Sep; 311(3):C366-77. PubMed ID: 27335171
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane.
    Ivetac I; Munday AD; Kisseleva MV; Zhang XM; Luff S; Tiganis T; Whisstock JC; Rowe T; Majerus PW; Mitchell CA
    Mol Biol Cell; 2005 May; 16(5):2218-33. PubMed ID: 15716355
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Acquisition of unprecedented phosphatidylinositol 3,5-bisphosphate rise in hyperosmotically stressed 3T3-L1 adipocytes, mediated by ArPIKfyve-PIKfyve pathway.
    Sbrissa D; Shisheva A
    J Biol Chem; 2005 Mar; 280(9):7883-9. PubMed ID: 15546865
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Apilimod, a candidate anticancer therapeutic, arrests not only PtdIns(3,5)P2 but also PtdIns5P synthesis by PIKfyve and induces bafilomycin A1-reversible aberrant endomembrane dilation.
    Sbrissa D; Naisan G; Ikonomov OC; Shisheva A
    PLoS One; 2018; 13(9):e0204532. PubMed ID: 30240452
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ebola virus requires phosphatidylinositol (3,5) bisphosphate production for efficient viral entry.
    Qiu S; Leung A; Bo Y; Kozak RA; Anand SP; Warkentin C; Salambanga FDR; Cui J; Kobinger G; Kobasa D; Côté M
    Virology; 2018 Jan; 513():17-28. PubMed ID: 29031163
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PIKfyve activity regulates reformation of terminal storage lysosomes from endolysosomes.
    Bissig C; Hurbain I; Raposo G; van Niel G
    Traffic; 2017 Nov; 18(11):747-757. PubMed ID: 28857423
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activity.
    Sbrissa D; Ikonomov OC; Strakova J; Dondapati R; Mlak K; Deeb R; Silver R; Shisheva A
    Mol Cell Biol; 2004 Dec; 24(23):10437-47. PubMed ID: 15542851
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.