242 related articles for article (PubMed ID: 17560110)
1. 3-Hydroxy-1,5-dihydro-pyrrol-2-one derivatives as advanced inhibitors of HIV integrase.
Kawasuji T; Fuji M; Yoshinaga T; Sato A; Fujiwara T; Kiyama R
Bioorg Med Chem; 2007 Aug; 15(16):5487-92. PubMed ID: 17560110
[TBL] [Abstract][Full Text] [Related]
2. A platform for designing HIV integrase inhibitors. Part 2: a two-metal binding model as a potential mechanism of HIV integrase inhibitors.
Kawasuji T; Fuji M; Yoshinaga T; Sato A; Fujiwara T; Kiyama R
Bioorg Med Chem; 2006 Dec; 14(24):8420-9. PubMed ID: 17005407
[TBL] [Abstract][Full Text] [Related]
3. A platform for designing HIV integrase inhibitors. Part 1: 2-hydroxy-3-heteroaryl acrylic acid derivatives as novel HIV integrase inhibitor and modeling of hydrophilic and hydrophobic pharmacophores.
Kawasuji T; Yoshinaga T; Sato A; Yodo M; Fujiwara T; Kiyama R
Bioorg Med Chem; 2006 Dec; 14(24):8430-45. PubMed ID: 17010623
[TBL] [Abstract][Full Text] [Related]
4. Design and optimization of tricyclic phtalimide analogues as novel inhibitors of HIV-1 integrase.
Verschueren WG; Dierynck I; Amssoms KI; Hu L; Boonants PM; Pille GM; Daeyaert FF; Hertogs K; Surleraux DL; Wigerinck PB
J Med Chem; 2005 Mar; 48(6):1930-40. PubMed ID: 15771437
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and antiviral activity of 7-benzyl-4-hydroxy-1,5-naphthyridin-2(1H)-one HIV integrase inhibitors.
Boros EE; Edwards CE; Foster SA; Fuji M; Fujiwara T; Garvey EP; Golden PL; Hazen RJ; Jeffrey JL; Johns BA; Kawasuji T; Kiyama R; Koble CS; Kurose N; Miller WH; Mote AL; Murai H; Sato A; Thompson JB; Woodward MC; Yoshinaga T
J Med Chem; 2009 May; 52(9):2754-61. PubMed ID: 19374386
[TBL] [Abstract][Full Text] [Related]
6. Tricyclic HIV integrase inhibitors: VI. SAR studies of 'benzyl flipped' C3-substituted pyrroloquinolines.
Metobo S; Mish M; Jin H; Jabri S; Lansdown R; Chen X; Tsiang M; Wright M; Kim CU
Bioorg Med Chem Lett; 2009 Feb; 19(4):1187-90. PubMed ID: 19167883
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological evaluation of purine derivatives incorporating metal chelating ligands as HIV integrase inhibitors.
Li X; Vince R
Bioorg Med Chem; 2006 Aug; 14(16):5742-55. PubMed ID: 16753300
[TBL] [Abstract][Full Text] [Related]
8. Synthesis of 5-(1-H or 1-alkyl-5-oxopyrrolidin-3-yl)-8-hydroxy-[1,6]-naphthyridine-7-carboxamide inhibitors of HIV-1 integrase.
Melamed JY; Egbertson MS; Varga S; Vacca JP; Moyer G; Gabryelski L; Felock PJ; Stillmock KA; Witmer MV; Schleif W; Hazuda DJ; Leonard Y; Jin L; Ellis JD; Young SD
Bioorg Med Chem Lett; 2008 Oct; 18(19):5307-10. PubMed ID: 18774711
[TBL] [Abstract][Full Text] [Related]
9. Amide-containing diketoacids as HIV-1 integrase inhibitors: synthesis, structure-activity relationship analysis, and biological activity.
Li H; Wang C; Sanchez T; Tan Y; Jiang C; Neamati N; Zhao G
Bioorg Med Chem; 2009 Apr; 17(7):2913-9. PubMed ID: 19269185
[TBL] [Abstract][Full Text] [Related]
10. Design and synthesis of novel nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors from caffeic acid phenethyl ester.
Wang P; Liu C; Sanches T; Zhong Y; Liu B; Xiong J; Neamati N; Zhao G
Bioorg Med Chem Lett; 2009 Aug; 19(16):4574-8. PubMed ID: 19625188
[TBL] [Abstract][Full Text] [Related]
11. Triketoacid inhibitors of HIV-integrase: a new chemotype useful for probing the integrase pharmacophore.
Walker MA; Johnson T; Ma Z; Banville J; Remillard R; Kim O; Zhang Y; Staab A; Wong H; Torri A; Samanta H; Lin Z; Deminie C; Terry B; Krystal M; Meanwell N
Bioorg Med Chem Lett; 2006 Jun; 16(11):2920-4. PubMed ID: 16546383
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, biological evaluation and molecular modeling studies of quinolonyl diketo acid derivatives: new structural insight into the HIV-1 integrase inhibition.
Vandurm P; Guiguen A; Cauvin C; Georges B; Le Van K; Michaux C; Cardona C; Mbemba G; Mouscadet JF; Hevesi L; Van Lint C; Wouters J
Eur J Med Chem; 2011 May; 46(5):1749-56. PubMed ID: 21385662
[TBL] [Abstract][Full Text] [Related]
13. Benzyl amide-ketoacid inhibitors of HIV-integrase.
Walker MA; Johnson T; Naidu BN; Banville J; Remillard R; Plamondon S; Martel A; Li C; Torri A; Samanta H; Lin Z; Dicker I; Krystal M; Meanwell NA
Bioorg Med Chem Lett; 2007 Sep; 17(17):4886-90. PubMed ID: 17604626
[TBL] [Abstract][Full Text] [Related]
14. Conformationally restrained carbazolone-containing alpha,gamma-diketo acids as inhibitors of HIV integrase.
Li X; Vince R
Bioorg Med Chem; 2006 May; 14(9):2942-55. PubMed ID: 16386908
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis, and anti-integrase activity of catechol-DKA hybrids.
Maurin C; Bailly F; Mbemba G; Mouscadet JF; Cotelle P
Bioorg Med Chem; 2006 May; 14(9):2978-84. PubMed ID: 16412645
[TBL] [Abstract][Full Text] [Related]
16. From ligand to complexes. Part 2. Remarks on human immunodeficiency virus type 1 integrase inhibition by beta-diketo acid metal complexes.
Bacchi A; Biemmi M; Carcelli M; Carta F; Compari C; Fisicaro E; Rogolino D; Sechi M; Sippel M; Sotriffer CA; Sanchez TW; Neamati N
J Med Chem; 2008 Nov; 51(22):7253-64. PubMed ID: 18983138
[TBL] [Abstract][Full Text] [Related]
17. Design and synthesis of substituted 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamides, novel HIV-1 integrase inhibitors.
Langford HM; Williams PD; Homnick CF; Vacca JP; Felock PJ; Stillmock KA; Witmer MV; Hazuda DJ; Gabryelski LJ; Schleif WA
Bioorg Med Chem Lett; 2008 Jan; 18(2):721-5. PubMed ID: 18078751
[TBL] [Abstract][Full Text] [Related]
18. Ethyl malonate amides: a diketo acid offspring fragment for HIV integrase inhibition.
Serafin K; Mazur P; Bak A; Laine E; Tchertanov L; Mouscadet JF; Polanski J
Bioorg Med Chem; 2011 Aug; 19(16):5000-5. PubMed ID: 21767953
[TBL] [Abstract][Full Text] [Related]
19. Naphthoxazepine inhibitors of HIV-1 integrase: synthesis and biological evaluation.
Garofalo A; Grande F; Brizzi A; Aiello F; Dayam R; Neamati N
ChemMedChem; 2008 Jun; 3(6):986-90. PubMed ID: 18383063
[TBL] [Abstract][Full Text] [Related]
20. 4-Hydroxy-5-pyrrolinone-3-carboxamide HIV-1 integrase inhibitors.
Pace P; Spieser SA; Summa V
Bioorg Med Chem Lett; 2008 Jul; 18(14):3865-9. PubMed ID: 18595690
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]