These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 17565155)

  • 1. Structural basis for depletion of heat shock protein 90 client proteins by deguelin.
    Oh SH; Woo JK; Yazici YD; Myers JN; Kim WY; Jin Q; Hong SS; Park HJ; Suh YG; Kim KW; Hong WK; Lee HY
    J Natl Cancer Inst; 2007 Jun; 99(12):949-61. PubMed ID: 17565155
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and Evaluation of a Novel Deguelin Derivative, L80, which Disrupts ATP Binding to the C-terminal Domain of Heat Shock Protein 90.
    Lee SC; Min HY; Choi H; Kim HS; Kim KC; Park SJ; Seong MA; Seo JH; Park HJ; Suh YG; Kim KW; Hong HS; Kim H; Lee MY; Lee J; Lee HY
    Mol Pharmacol; 2015 Aug; 88(2):245-55. PubMed ID: 25976766
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis.
    Chang DJ; An H; Kim KS; Kim HH; Jung J; Lee JM; Kim NJ; Han YT; Yun H; Lee S; Lee G; Lee S; Lee JS; Cha JH; Park JH; Park JW; Lee SC; Kim SG; Kim JH; Lee HY; Kim KW; Suh YG
    J Med Chem; 2012 Dec; 55(24):10863-84. PubMed ID: 23186287
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors.
    Kim HS; Hong M; Ann J; Yoon S; Nguyen CT; Lee SC; Lee HY; Suh YG; Seo JH; Choi H; Kim JY; Kim KW; Kim J; Kim YM; Park SJ; Park HJ; Lee J
    Bioorg Med Chem; 2016 Nov; 24(22):6082-6093. PubMed ID: 27745993
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of novel antiangiogenic anticancer activities of deguelin targeting hypoxia-inducible factor-1 alpha.
    Oh SH; Woo JK; Jin Q; Kang HJ; Jeong JW; Kim KW; Hong WK; Lee HY
    Int J Cancer; 2008 Jan; 122(1):5-14. PubMed ID: 17764071
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Investigation of B,C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents.
    Kim HS; Hoang VH; Hong M; Chul Kim K; Ann J; Nguyen CT; Seo JH; Choi H; Yong Kim J; Kim KW; Sub Byun W; Lee S; Lee S; Suh YG; Chen J; Park HJ; Cho TM; Kim JY; Seo JH; Lee J
    Bioorg Med Chem; 2019 Apr; 27(7):1370-1381. PubMed ID: 30827868
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypoxia-inducible factor 1alpha and antiangiogenic activity of farnesyltransferase inhibitor SCH66336 in human aerodigestive tract cancer.
    Han JY; Oh SH; Morgillo F; Myers JN; Kim E; Hong WK; Lee HY
    J Natl Cancer Inst; 2005 Sep; 97(17):1272-86. PubMed ID: 16145048
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ring-truncated deguelin derivatives as potent Hypoxia Inducible Factor-1α (HIF-1α) inhibitors.
    Kim HS; Hong M; Lee SC; Lee HY; Suh YG; Oh DC; Seo JH; Choi H; Kim JY; Kim KW; Kim JH; Kim J; Kim YM; Park SJ; Park HJ; Lee J
    Eur J Med Chem; 2015 Nov; 104():157-64. PubMed ID: 26457742
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Degradation of HIF-1alpha under hypoxia combined with induction of Hsp90 polyubiquitination in cancer cells by hypericin: a unique cancer therapy.
    Barliya T; Mandel M; Livnat T; Weinberger D; Lavie G
    PLoS One; 2011; 6(9):e22849. PubMed ID: 21949677
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of deguelin-biotin conjugates and investigation into deguelin's interactions.
    Garcia J; Barluenga S; Gorska K; Sasse F; Winssinger N
    Bioorg Med Chem; 2012 Jan; 20(2):672-80. PubMed ID: 22037048
    [TBL] [Abstract][Full Text] [Related]  

  • 11. C-Terminal HSP90 Inhibitors Block the HIF-1 Hypoxic Response by Degrading HIF-1α through the Oxygen-Dependent Degradation Pathway.
    Kataria N; Martinez CA; Kerr B; Zaiter SS; Morgan M; McAlpine SR; Cook KM
    Cell Physiol Biochem; 2019; 53(3):480-495. PubMed ID: 31486323
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Docosahexaenoic Acid-mediated Inhibition of Heat Shock Protein 90-p23 Chaperone Complex and Downstream Client Proteins in Lung and Breast Cancer.
    Mouradian M; Ma IV; Vicente ED; Kikawa KD; Pardini RS
    Nutr Cancer; 2017 Jan; 69(1):92-104. PubMed ID: 27880046
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of novel anti-breast cancer agents derived from deguelin as inhibitors of heat shock protein 90 (HSP90).
    Nguyen CT; Ann J; Sahu R; Byun WS; Lee S; Nam G; Park HJ; Park S; Kim YJ; Kim JY; Seo JH; Lee J
    Bioorg Med Chem Lett; 2020 Sep; 30(17):127374. PubMed ID: 32738983
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, and biological evaluation of truncated deguelin derivatives as Hsp90 inhibitors.
    Yao H; Xu F; Wang G; Xie S; Li W; Yao H; Ma C; Zhu Z; Xu J; Xu S
    Eur J Med Chem; 2019 Apr; 167():485-498. PubMed ID: 30784881
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel C-terminal heat shock protein 90 inhibitor that overcomes STAT3-Wnt-β-catenin signaling-mediated drug resistance and adverse effects.
    Lee HJ; Min HY; Yong YS; Ann J; Nguyen CT; La MT; Hyun SY; Le HT; Kim H; Kwon H; Nam G; Park HJ; Lee J; Lee HY
    Theranostics; 2022; 12(1):105-125. PubMed ID: 34987637
    [No Abstract]   [Full Text] [Related]  

  • 16. HSP90 inhibits apoptosis and promotes growth by regulating HIF-1α abundance in hepatocellular carcinoma.
    Liu X; Chen S; Tu J; Cai W; Xu Q
    Int J Mol Med; 2016 Mar; 37(3):825-35. PubMed ID: 26846697
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hemin, an iron-binding porphyrin, inhibits HIF-1α induction through its binding with heat shock protein 90.
    Lee JM; Lee WH; Kay HY; Kim ES; Moon A; Kim SG
    Int J Cancer; 2012 Feb; 130(3):716-27. PubMed ID: 21413014
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A group of novel HIF-1α inhibitors, glyceollins, blocks HIF-1α synthesis and decreases its stability via inhibition of the PI3K/AKT/mTOR pathway and Hsp90 binding.
    Lee SH; Jee JG; Bae JS; Liu KH; Lee YM
    J Cell Physiol; 2015 Apr; 230(4):853-62. PubMed ID: 25204544
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deguelin Analogue SH-1242 Inhibits Hsp90 Activity and Exerts Potent Anticancer Efficacy with Limited Neurotoxicity.
    Lee SC; Min HY; Choi H; Bae SY; Park KH; Hyun SY; Lee HJ; Moon J; Park SH; Kim JY; An H; Park SJ; Seo JH; Lee S; Kim YM; Park HJ; Lee SK; Lee J; Lee J; Kim KW; Suh YG; Lee HY
    Cancer Res; 2016 Feb; 76(3):686-99. PubMed ID: 26645561
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket.
    Donnelly A; Blagg BS
    Curr Med Chem; 2008; 15(26):2702-17. PubMed ID: 18991631
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.