157 related articles for article (PubMed ID: 17566746)
1. Synthesis, resolution, stereochemistry, and molecular modeling of (R)- and (S)-2-acetyl-1-(4'-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline AMPAR antagonists.
Gitto R; Ficarra R; Stancanelli R; Guardo M; De Luca L; Barreca ML; Pagano B; Rotondo A; Bruno G; Russo E; De Sarro G; Chimirri A
Bioorg Med Chem; 2007 Aug; 15(16):5417-23. PubMed ID: 17566746
[TBL] [Abstract][Full Text] [Related]
2. Discovery of a novel and highly potent noncompetitive AMPA receptor antagonist.
Gitto R; Barreca ML; De Luca L; De Sarro G; Ferreri G; Quartarone S; Russo E; Constanti A; Chimirri A
J Med Chem; 2003 Jan; 46(1):197-200. PubMed ID: 12502375
[TBL] [Abstract][Full Text] [Related]
3. Excitatory amino acid receptor antagonists: resolution, absolute stereochemistry, and pharmacology of (S)- and (R)-2-amino-2-(5-tert-butyl-3-hydroxyisoxazol-4-yl)acetic acid (ATAA).
Johansen TN; Frydenvang K; Ebert B; Madsen U; Krogsgaard-Larsen P
Chirality; 1997; 9(5-6):529-36. PubMed ID: 9329180
[TBL] [Abstract][Full Text] [Related]
4. Resolution, absolute stereochemistry, and enantiopharmacology of the GluR1-4 and GluR5 antagonist 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid.
Møller EH; Egebjerg J; Brehm L; Stensbøl TB; Johansen TN; Madsen U; Krogsgaard-Larsen P
Chirality; 1999; 11(10):752-9. PubMed ID: 10561704
[TBL] [Abstract][Full Text] [Related]
5. Bis-tetrahydroisoquinoline derivatives: structure analysis of the three stereoisomers of 1,1'-(propane-1,3-diyl)-bis-(6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline).
Wouters J; Elasaad K; Norberg B; Graulich A; Liégeois JF
Eur J Med Chem; 2010 Jul; 45(7):3240-4. PubMed ID: 20381214
[TBL] [Abstract][Full Text] [Related]
6. Synthesis, theoretical and structural analyses, and enantiopharmacology of 3-carboxy homologs of AMPA.
Brehm L; Greenwood JR; Sløk FA; Holm MM; Nielsen B; Geneser U; Stensbøl TB; Bräuner-Osborne H; Begtrup M; Egebjerg J; Krogsgaard-Larsen P
Chirality; 2004 Aug; 16(7):452-66. PubMed ID: 15236343
[TBL] [Abstract][Full Text] [Related]
7. Closing in on the AMPA receptor: synthesis and evaluation of 2-acetyl-1-(4'-chlorophenyl)-6-methoxy-7-[11C]methoxy-1,2,3,4-tetrahydroisoquinoline as a potential PET tracer.
Arstad E; Gitto R; Chimirri A; Caruso R; Constanti A; Turton D; Hume SP; Ahmad R; Pilowsky LS; Luthra SK
Bioorg Med Chem; 2006 Jul; 14(14):4712-7. PubMed ID: 16621575
[TBL] [Abstract][Full Text] [Related]
8. Improvement of water solubility of non-competitive AMPA receptor antagonists by complexation with beta-cyclodextrin.
Stancanelli R; Crupi V; De Luca L; Ficarra P; Ficarra R; Gitto R; Guardo M; Iraci N; Majolino D; Tommasini S; Venuti V
Bioorg Med Chem; 2008 Sep; 16(18):8706-12. PubMed ID: 18762428
[TBL] [Abstract][Full Text] [Related]
9. Glutamate receptor ligands: synthesis, stereochemistry, and enantiopharmacology of methylated 2-aminoadipic acid analogs.
Guldbrandt M; Johansen TN; Frydenvang K; Bräuner-Osborne H; Stensbøl TB; Nielsen B; Karla R; Santi F; Krogsgaard-Larsen P; Madsen U
Chirality; 2002 May; 14(4):351-63. PubMed ID: 11968078
[TBL] [Abstract][Full Text] [Related]
10. Novel potent anticonvulsant agent containing a tetrahydroisoquinoline skeleton.
Gitto R; Caruso R; Pagano B; De Luca L; Citraro R; Russo E; De Sarro G; Chimirri A
J Med Chem; 2006 Sep; 49(18):5618-22. PubMed ID: 16942035
[TBL] [Abstract][Full Text] [Related]
11. Synthesis, chiral resolution and pharmacological evaluation of a 2,3-benzodiazepine-derived noncompetitive AMPA receptor antagonist.
Calabrò ML; Raneri D; Ficarra P; Mennini T; Colleoni S; Grazioso G; Micale N; Zappalà M; Grasso S
ChemMedChem; 2009 Mar; 4(3):415-20. PubMed ID: 19137515
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, chiral resolution, and enantiopharmacology of a potent 2,3-benzodiazepine derivative as noncompetitive AMPA receptor antagonist.
Zappalà M; Postorino G; Micale N; Caccamese S; Parrinello N; Grazioso G; Roda G; Menniti FS; De Sarro G; Grasso S
J Med Chem; 2006 Jan; 49(2):575-81. PubMed ID: 16420043
[TBL] [Abstract][Full Text] [Related]
13. Synthesis of carbon-11 and fluorine-18 labeled N-acetyl-1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives as new potential PET AMPA receptor ligands.
Gao M; Kong D; Clearfield A; Zheng QH
Bioorg Med Chem Lett; 2006 Apr; 16(8):2229-33. PubMed ID: 16455250
[TBL] [Abstract][Full Text] [Related]
14. Optimization of a LC method for the enantioseparation of a non-competitive glutamate receptor antagonist, by experimental design methodology.
Donato P; Stancanelli R; Calabrò ML; Tommasini S; Cutroneo P; Guardo M; Pagano B; Chimirri A; Ficarra P; Ficarra R
J Pharm Biomed Anal; 2006 Nov; 42(5):543-8. PubMed ID: 16860510
[TBL] [Abstract][Full Text] [Related]
15. Reassessing the melatonin pharmacophore--enantiomeric resolution, pharmacological activity, structure analysis, and molecular modeling of a constrained chiral melatonin analogue.
Rivara S; Diamantini G; Di Giacomo B; Lamba D; Gatti G; Lucini V; Pannacci M; Mor M; Spadoni G; Tarzia G
Bioorg Med Chem; 2006 May; 14(10):3383-91. PubMed ID: 16431121
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and anticonvulsant properties of tetrahydroisoquinoline derivatives.
Gitto R; Caruso R; Orlando V; Quartarone S; Barreca ML; Ferreri G; Russo E; De Sarro G; Chimirri A
Farmaco; 2004 Jan; 59(1):7-12. PubMed ID: 14751310
[TBL] [Abstract][Full Text] [Related]
17. A stereochemical anomaly: the cyclised (R)-AMPA analogue (R)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-5-carboxylic acid [(R)-5-HPCA] resembles (S)-AMPA at glutamate receptors.
Vogensen SB; Greenwood JR; Varming AR; Brehm L; Pickering DS; Nielsen B; Liljefors T; Clausen RP; Johansen TN; Krogsgaard-Larsen P
Org Biomol Chem; 2004 Jan; 2(2):206-13. PubMed ID: 14737644
[TBL] [Abstract][Full Text] [Related]
18. Preparative resolution of 1-aminoindan-1,5-dicarboxylic acid (AIDA) by chiral ligand-exchange chromatography.
Natalini B; Marinozzi M; Bade K; Sardella R; Thomsen C; Pellicciari R
Chirality; 2004 May; 16(5):314-7. PubMed ID: 15069662
[TBL] [Abstract][Full Text] [Related]
19. Synthesis of chiral 1-substituted tetrahydroisoquinolines by the intramolecular 1,3-chirality transfer reaction catalyzed by Bi(OTf)3.
Kawai N; Abe R; Matsuda M; Uenishi J
J Org Chem; 2011 Apr; 76(7):2102-14. PubMed ID: 21355532
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and structure-active relationship of 1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline anticonvulsants.
Gitto R; De Luca L; Ferro S; Agnello S; Russo E; De Sarro G; Chimirri A
Chem Pharm Bull (Tokyo); 2010 Dec; 58(12):1602-5. PubMed ID: 21139262
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]