These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 17570666)

  • 1. Novel tetrahydro-beta-carboline-1-carboxylic acids as inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2).
    Trujillo JI; Meyers MJ; Anderson DR; Hegde S; Mahoney MW; Vernier WF; Buchler IP; Wu KK; Yang S; Hartmann SJ; Reitz DB
    Bioorg Med Chem Lett; 2007 Aug; 17(16):4657-63. PubMed ID: 17570666
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2).
    Anderson DR; Meyers MJ; Vernier WF; Mahoney MW; Kurumbail RG; Caspers N; Poda GI; Schindler JF; Reitz DB; Mourey RJ
    J Med Chem; 2007 May; 50(11):2647-54. PubMed ID: 17480064
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The discovery of carboline analogs as potent MAPKAP-K2 inhibitors.
    Wu JP; Wang J; Abeywardane A; Andersen D; Emmanuel M; Gautschi E; Goldberg DR; Kashem MA; Lukas S; Mao W; Martin L; Morwick T; Moss N; Pargellis C; Patel UR; Patnaude L; Peet GW; Skow D; Snow RJ; Ward Y; Werneburg B; White A
    Bioorg Med Chem Lett; 2007 Aug; 17(16):4664-9. PubMed ID: 17576063
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aminocyanopyridine inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2).
    Anderson DR; Hegde S; Reinhard E; Gomez L; Vernier WF; Lee L; Liu S; Sambandam A; Snider PA; Masih L
    Bioorg Med Chem Lett; 2005 Mar; 15(6):1587-90. PubMed ID: 15745802
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and cytotoxic activities of beta-carboline amino acid ester conjugates.
    Zhao M; Bi L; Wang W; Wang C; Baudy-Floc'h M; Ju J; Peng S
    Bioorg Med Chem; 2006 Oct; 14(20):6998-7010. PubMed ID: 16806943
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Analysis of monoamine oxidase enzymatic activity by reversed-phase high performance liquid chromatography and inhibition by beta-carboline alkaloids occurring in foods and plants.
    Herraiz T; Chaparro C
    J Chromatogr A; 2006 Jul; 1120(1-2):237-43. PubMed ID: 16386263
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A class of 3S-2-aminoacyltetrahydro-beta-carboline-3-carboxylic acids: their facile synthesis, inhibition for platelet activation, and high in vivo anti-thrombotic potency.
    Liu J; Jiang X; Zhao M; Zhang X; Zheng M; Peng L; Peng S
    J Med Chem; 2010 Apr; 53(8):3106-16. PubMed ID: 20329729
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel 1-(2-aminopyrazin-3-yl)methyl-2-thioureas as potent inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2).
    Lin S; Lombardo M; Malkani S; Hale JJ; Mills SG; Chapman K; Thompson JE; Zhang WX; Wang R; Cubbon RM; O'Neill EA; Luell S; Carballo-Jane E; Yang L
    Bioorg Med Chem Lett; 2009 Jun; 19(12):3238-42. PubMed ID: 19423344
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, in vitro anti-inflammatory and cytotoxic evaluation, and mechanism of action studies of 1-benzoyl-β-carboline and 1-benzoyl-3-carboxy-β-carboline derivatives.
    Yang ML; Kuo PC; Hwang TL; Chiou WF; Qian K; Lai CY; Lee KH; Wu TS
    Bioorg Med Chem; 2011 Mar; 19(5):1674-82. PubMed ID: 21316977
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel β-carboline-tripeptide conjugates attenuate mesenteric ischemia/reperfusion injury in the rat.
    Bi W; Bi Y; Xue P; Zhang Y; Gao X; Wang Z; Li M; Baudy-Floc'h M; Ngerebara N; Li X; Gibson KM; Bi L
    Eur J Med Chem; 2011 Jun; 46(6):2441-52. PubMed ID: 21474215
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Anti-inflammatory properties of a novel N-phenyl pyridinone inhibitor of p38 mitogen-activated protein kinase: preclinical-to-clinical translation.
    Hope HR; Anderson GD; Burnette BL; Compton RP; Devraj RV; Hirsch JL; Keith RH; Li X; Mbalaviele G; Messing DM; Saabye MJ; Schindler JF; Selness SR; Stillwell LI; Webb EG; Zhang J; Monahan JB
    J Pharmacol Exp Ther; 2009 Dec; 331(3):882-95. PubMed ID: 19720877
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological activity of N-aroyl-tetrahydro-gamma-carbolines.
    Bridoux A; Millet R; Pommery J; Pommery N; Henichart JP
    Bioorg Med Chem; 2010 Jun; 18(11):3910-24. PubMed ID: 20451397
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and anti-inflammatory properties of orally active 4-(phenylamino)-pyrrolo[2,1-f][1,2,4]triazine p38alpha mitogen-activated protein kinase inhibitors.
    Hynes J; Dyckman AJ; Lin S; Wrobleski ST; Wu H; Gillooly KM; Kanner SB; Lonial H; Loo D; McIntyre KW; Pitt S; Shen DR; Shuster DJ; Yang X; Zhang R; Behnia K; Zhang H; Marathe PH; Doweyko AM; Tokarski JS; Sack JS; Pokross M; Kiefer SE; Newitt JA; Barrish JC; Dodd J; Schieven GL; Leftheris K
    J Med Chem; 2008 Jan; 51(1):4-16. PubMed ID: 18072718
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, crystal structure and biological activity of beta-carboline based selective CDK4-cyclin D1 inhibitors.
    García MD; Wilson AJ; Emmerson DP; Jenkins PR; Mahale S; Chaudhuri B
    Org Biomol Chem; 2006 Dec; 4(24):4478-84. PubMed ID: 17268643
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Part 1: Structure-Activity Relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase.
    Wurz RP; Pettus LH; Xu S; Henkle B; Sherman L; Plant M; Miner K; McBride H; Wong LM; Saris CJ; Lee MR; Chmait S; Mohr C; Hsieh F; Tasker AS
    Bioorg Med Chem Lett; 2009 Aug; 19(16):4724-8. PubMed ID: 19574047
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification and SAR of squarate inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2).
    Lovering F; Kirincich S; Wang W; Combs K; Resnick L; Sabalski JE; Butera J; Liu J; Parris K; Telliez JB
    Bioorg Med Chem; 2009 May; 17(9):3342-51. PubMed ID: 19364658
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity.
    Martin MW; Newcomb J; Nunes JJ; Boucher C; Chai L; Epstein LF; Faust T; Flores S; Gallant P; Gore A; Gu Y; Hsieh F; Huang X; Kim JL; Middleton S; Morgenstern K; Oliveira-dos-Santos A; Patel VF; Powers D; Rose P; Tudor Y; Turci SM; Welcher AA; Zack D; Zhao H; Zhu L; Zhu X; Ghiron C; Ermann M; Johnston D; Saluste CG
    J Med Chem; 2008 Mar; 51(6):1637-48. PubMed ID: 18278858
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure determination of a tetrahydro-beta-carboline of arthropod origin: a novel alkaloid-toxin subclass from the web of spider Nephila clavipes.
    Marques MR; Mendes MA; Tormena CF; Souza BM; Cesar LM; Rittner R; Palma MS
    Chem Biodivers; 2005 Apr; 2(4):525-34. PubMed ID: 17192002
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A class of oral N-[(1S,3S)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carbonyl]- N'-(amino-acid-acyl)hydrazine: discovery, synthesis, in vitro anti-platelet aggregation/in vivo anti-thrombotic evaluation and 3D QSAR analysis.
    Yao K; Zhao M; Zhang X; Wang Y; Li L; Zheng M; Peng S
    Eur J Med Chem; 2011 Aug; 46(8):3237-49. PubMed ID: 21571404
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antiplatelet activity of beta-carboline alkaloids from Perganum harmala: a possible mechanism through inhibiting PLCgamma2 phosphorylation.
    Im JH; Jin YR; Lee JJ; Yu JY; Han XH; Im SH; Hong JT; Yoo HS; Pyo MY; Yun YP
    Vascul Pharmacol; 2009; 50(5-6):147-52. PubMed ID: 19073282
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.