260 related articles for article (PubMed ID: 17571247)
1. Potential advantages of DNA methyltransferase 1 (DNMT1)-targeted inhibition for cancer therapy.
Jung Y; Park J; Kim TY; Park JH; Jong HS; Im SA; Robertson KD; Bang YJ; Kim TY
J Mol Med (Berl); 2007 Oct; 85(10):1137-48. PubMed ID: 17571247
[TBL] [Abstract][Full Text] [Related]
2. Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation.
Reu FJ; Bae SI; Cherkassky L; Leaman DW; Lindner D; Beaulieu N; MacLeod AR; Borden EC
J Clin Oncol; 2006 Aug; 24(23):3771-9. PubMed ID: 16801630
[TBL] [Abstract][Full Text] [Related]
3. [Effects of 5-Aza-2'-deoxycytidine and trichostatin A on DNA methylation and expression of hMLH1 in ovarian cancer cell line COC1/DDP].
Meng CF; Dai DQ; Guo KJ
Ai Zheng; 2008 Dec; 27(12):1251-5. PubMed ID: 19079988
[TBL] [Abstract][Full Text] [Related]
4. Consequences of combining siRNA-mediated DNA methyltransferase 1 depletion with 5-aza-2'-deoxycytidine in human leukemic KG1 cells.
Vispé S; Deroide A; Davoine E; Desjobert C; Lestienne F; Fournier L; Novosad N; Bréand S; Besse J; Busato F; Tost J; De Vries L; Cussac D; Riond J; Arimondo PB
Oncotarget; 2015 Jun; 6(17):15265-82. PubMed ID: 25948775
[TBL] [Abstract][Full Text] [Related]
5. Cytotoxicity of 5-Aza-2'-deoxycytidine against gastric cancer involves DNA damage in an ATM-P53 dependent signaling pathway and demethylation of P16(INK4A).
Liu J; Xie YS; Wang FL; Zhang LJ; Zhang Y; Luo HS
Biomed Pharmacother; 2013 Feb; 67(1):78-87. PubMed ID: 23201008
[TBL] [Abstract][Full Text] [Related]
6. De novo DNA methyltransferases Dnmt3a and Dnmt3b primarily mediate the cytotoxic effect of 5-aza-2'-deoxycytidine.
Oka M; Meacham AM; Hamazaki T; Rodić N; Chang LJ; Terada N
Oncogene; 2005 Apr; 24(19):3091-9. PubMed ID: 15735669
[TBL] [Abstract][Full Text] [Related]
7. 5-Aza-2'-deoxycytidine induces cytotoxicity in BGC-823 cells via DNA methyltransferase 1 and 3a independent of p53 status.
Liu J; Zhang Y; Xie YS; Wang FL; Zhang LJ; Deng T; Luo HS
Oncol Rep; 2012 Aug; 28(2):545-52. PubMed ID: 22664909
[TBL] [Abstract][Full Text] [Related]
8. Effect of inhibition of MEK pathway on 5-aza-deoxycytidine-suppressed pancreatic cancer cell proliferation.
Wang X; Wang H; Jiang N; Lu W; Zhang XF; Fang JY
Genet Mol Res; 2013 Nov; 12(4):5560-73. PubMed ID: 24301926
[TBL] [Abstract][Full Text] [Related]
9. Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells.
Yang X; Phillips DL; Ferguson AT; Nelson WG; Herman JG; Davidson NE
Cancer Res; 2001 Oct; 61(19):7025-9. PubMed ID: 11585728
[TBL] [Abstract][Full Text] [Related]
10. 5-aza-2'-deoxycytidine-induced genome rearrangements are mediated by DNMT1.
Maslov AY; Lee M; Gundry M; Gravina S; Strogonova N; Tazearslan C; Bendebury A; Suh Y; Vijg J
Oncogene; 2012 Dec; 31(50):5172-9. PubMed ID: 22349820
[TBL] [Abstract][Full Text] [Related]
11. DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells.
Robert MF; Morin S; Beaulieu N; Gauthier F; Chute IC; Barsalou A; MacLeod AR
Nat Genet; 2003 Jan; 33(1):61-5. PubMed ID: 12496760
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer.
McCabe MT; Low JA; Daignault S; Imperiale MJ; Wojno KJ; Day ML
Cancer Res; 2006 Jan; 66(1):385-92. PubMed ID: 16397253
[TBL] [Abstract][Full Text] [Related]
13. DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer.
Mutze K; Langer R; Schumacher F; Becker K; Ott K; Novotny A; Hapfelmeier A; Höfler H; Keller G
Eur J Cancer; 2011 Aug; 47(12):1817-25. PubMed ID: 21458988
[TBL] [Abstract][Full Text] [Related]
14. Expression of RASSF1A, an epigenetically silenced tumor suppressor, overcomes resistance to apoptosis induction by interferons.
Reu FJ; Leaman DW; Maitra RR; Bae SI; Cherkassky L; Fox MW; Rempinski DR; Beaulieu N; MacLeod AR; Borden EC
Cancer Res; 2006 Mar; 66(5):2785-93. PubMed ID: 16510600
[TBL] [Abstract][Full Text] [Related]
15. Depletion of DNA methyltransferase 1 and/or DNA methyltransferase 3b mediates growth arrest and apoptosis in lung and esophageal cancer and malignant pleural mesothelioma cells.
Kassis ES; Zhao M; Hong JA; Chen GA; Nguyen DM; Schrump DS
J Thorac Cardiovasc Surg; 2006 Feb; 131(2):298-306. PubMed ID: 16434257
[TBL] [Abstract][Full Text] [Related]
16. Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation.
Leu YW; Rahmatpanah F; Shi H; Wei SH; Liu JC; Yan PS; Huang TH
Cancer Res; 2003 Oct; 63(19):6110-5. PubMed ID: 14559786
[TBL] [Abstract][Full Text] [Related]
17. Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach.
Gius D; Cui H; Bradbury CM; Cook J; Smart DK; Zhao S; Young L; Brandenburg SA; Hu Y; Bisht KS; Ho AS; Mattson D; Sun L; Munson PJ; Chuang EY; Mitchell JB; Feinberg AP
Cancer Cell; 2004 Oct; 6(4):361-71. PubMed ID: 15488759
[TBL] [Abstract][Full Text] [Related]
18. Change in gene expression profiles of secreted frizzled-related proteins (SFRPs) by sodium butyrate in gastric cancers: induction of promoter demethylation and histone modification causing inhibition of Wnt signaling.
Shin H; Kim JH; Lee YS; Lee YC
Int J Oncol; 2012 May; 40(5):1533-42. PubMed ID: 22246241
[TBL] [Abstract][Full Text] [Related]
19. DNMT3A and DNMT3B mediate autocrine hGH repression of plakoglobin gene transcription and consequent phenotypic conversion of mammary carcinoma cells.
Shafiei F; Rahnama F; Pawella L; Mitchell MD; Gluckman PD; Lobie PE
Oncogene; 2008 Apr; 27(18):2602-12. PubMed ID: 17998942
[TBL] [Abstract][Full Text] [Related]
20. 5-Aza-2'-deoxycytidine induces retinoic acid receptor-beta(2) demethylation and growth inhibition in esophageal squamous carcinoma cells.
Liu Z; Zhang L; Ding F; Li J; Guo M; Li W; Wang Y; Yu Z; Zhan Q; Wu M; Liu Z
Cancer Lett; 2005 Dec; 230(2):271-83. PubMed ID: 16297713
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
