BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 17572486)

  • 1. Examination of Glucocorticoid receptor alpha-mediated transcriptional regulation of P-glycoprotein, CYP3A4, and CYP2C9 genes in placental trophoblast cell lines.
    Pavek P; Cerveny L; Svecova L; Brysch M; Libra A; Vrzal R; Nachtigal P; Staud F; Ulrichova J; Fendrich Z; Dvorak Z
    Placenta; 2007 Oct; 28(10):1004-11. PubMed ID: 17572486
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
    Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dexamethasone-mediated up-regulation of human CYP2A6 involves the glucocorticoid receptor and increased binding of hepatic nuclear factor 4 alpha to the proximal promoter.
    Onica T; Nichols K; Larin M; Ng L; Maslen A; Dvorak Z; Pascussi JM; Vilarem MJ; Maurel P; Kirby GM
    Mol Pharmacol; 2008 Feb; 73(2):451-60. PubMed ID: 17978169
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transcriptional activation of CYP2C9, CYP1A1, and CYP1A2 by hepatocyte nuclear factor 4alpha requires coactivators peroxisomal proliferator activated receptor-gamma coactivator 1alpha and steroid receptor coactivator 1.
    Martínez-Jiménez CP; Castell JV; Gómez-Lechón MJ; Jover R
    Mol Pharmacol; 2006 Nov; 70(5):1681-92. PubMed ID: 16882880
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Induction of cytochrome P450 (CYP)1A1, CYP1A2, and CYP3A4 but not of CYP2C9, CYP2C19, multidrug resistance (MDR-1) and multidrug resistance associated protein (MRP-1) by prototypical inducers in human hepatocytes.
    Runge D; Köhler C; Kostrubsky VE; Jäger D; Lehmann T; Runge DM; May U; Stolz DB; Strom SC; Fleig WE; Michalopoulos GK
    Biochem Biophys Res Commun; 2000 Jun; 273(1):333-41. PubMed ID: 10873607
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha.
    Ferguson SS; Chen Y; LeCluyse EL; Negishi M; Goldstein JA
    Mol Pharmacol; 2005 Sep; 68(3):747-57. PubMed ID: 15933212
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Aryl hydrocarbon receptor and aryl hydrocarbon nuclear translocator expression in human and rat placentas and transcription activity in human trophoblast cultures.
    Stejskalova L; Vecerova L; Peréz LM; Vrzal R; Dvorak Z; Nachtigal P; Pavek P
    Toxicol Sci; 2011 Sep; 123(1):26-36. PubMed ID: 21666223
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation.
    Dvorak Z; Modriansky M; Pichard-Garcia L; Balaguer P; Vilarem MJ; Ulrichová J; Maurel P; Pascussi JM
    Mol Pharmacol; 2003 Jul; 64(1):160-9. PubMed ID: 12815172
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dexamethasone accelerates degradation of aryl hydrocarbon receptor (AHR) and suppresses CYP1A1 induction in placental JEG-3 cell line.
    Stejskalova L; Rulcova A; Vrzal R; Dvorak Z; Pavek P
    Toxicol Lett; 2013 Nov; 223(2):183-91. PubMed ID: 24091107
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glucocorticoid receptor-mediated insulin-like growth factor-I transcriptional regulation in BeWo trophoblast cells before and after syncytialisation.
    He B; Zhang N; Jia Y; Sun Q; Zhao R
    Steroids; 2016 Nov; 115():26-33. PubMed ID: 27500692
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression.
    Li T; Chiang JY
    Drug Metab Dispos; 2006 May; 34(5):756-64. PubMed ID: 16455805
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4α upregulation in primary human hepatocytes.
    Rulcova A; Krausova L; Smutny T; Vrzal R; Dvorak Z; Jover R; Pavek P
    Pharmacol Rep; 2013; 65(5):1322-35. PubMed ID: 24399729
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Involvement of hepatocyte nuclear factor 4alpha in the different expression level between CYP2C9 and CYP2C19 in the human liver.
    Kawashima S; Kobayashi K; Takama K; Higuchi T; Furihata T; Hosokawa M; Chiba K
    Drug Metab Dispos; 2006 Jun; 34(6):1012-8. PubMed ID: 16540586
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of hepatocyte nuclear factors in transcriptional regulation of male-specific CYP2A2.
    Wiwi CA; Waxman DJ
    J Biol Chem; 2005 Feb; 280(5):3259-68. PubMed ID: 15539409
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hepatocyte nuclear factor 4{alpha} regulates rifampicin-mediated induction of CYP2C genes in primary cultures of human hepatocytes.
    Rana R; Chen Y; Ferguson SS; Kissling GE; Surapureddi S; Goldstein JA
    Drug Metab Dispos; 2010 Apr; 38(4):591-9. PubMed ID: 20086032
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Up-regulation of CYP expression in hepatoma cells stably transfected by chimeric nuclear receptors.
    Küblbeck J; Reinisalo M; Mustonen R; Honkakoski P
    Eur J Pharm Sci; 2010 Jul; 40(4):263-72. PubMed ID: 20381613
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.
    Tirona RG; Lee W; Leake BF; Lan LB; Cline CB; Lamba V; Parviz F; Duncan SA; Inoue Y; Gonzalez FJ; Schuetz EG; Kim RB
    Nat Med; 2003 Feb; 9(2):220-4. PubMed ID: 12514743
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gene expression of CYP3A4, ABC-transporters (MDR1 and MRP1-MRP5) and hPXR in three different human colon carcinoma cell lines.
    Pfrunder A; Gutmann H; Beglinger C; Drewe J
    J Pharm Pharmacol; 2003 Jan; 55(1):59-66. PubMed ID: 12625868
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nuclear receptor coactivator 6 mediates the synergistic activation of human cytochrome P-450 2C9 by the constitutive androstane receptor and hepatic nuclear factor-4alpha.
    Surapureddi S; Rana R; Reddy JK; Goldstein JA
    Mol Pharmacol; 2008 Sep; 74(3):913-23. PubMed ID: 18552123
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glucocorticoid receptor-independent transcriptional induction of cytochrome P450 3A1 by metyrapone and its potentiation by glucocorticoid.
    Wright MC; Wang XJ; Pimenta M; Ribeiro V; Paine AJ; Lechner MC
    Mol Pharmacol; 1996 Oct; 50(4):856-63. PubMed ID: 8863830
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.