These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

648 related articles for article (PubMed ID: 17574421)

  • 1. 9-Substituted berberine derivatives as G-quadruplex stabilizing ligands in telomeric DNA.
    Zhang WJ; Ou TM; Lu YJ; Huang YY; Wu WB; Huang ZS; Zhou JL; Wong KY; Gu LQ
    Bioorg Med Chem; 2007 Aug; 15(16):5493-501. PubMed ID: 17574421
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands.
    Ma Y; Ou TM; Tan JH; Hou JQ; Huang SL; Gu LQ; Huang ZS
    Bioorg Med Chem Lett; 2009 Jul; 19(13):3414-7. PubMed ID: 19477640
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 9-N-Substituted berberine derivatives: stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc.
    Ma Y; Ou TM; Hou JQ; Lu YJ; Tan JH; Gu LQ; Huang ZS
    Bioorg Med Chem; 2008 Aug; 16(16):7582-91. PubMed ID: 18674916
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.
    Lu YJ; Ou TM; Tan JH; Hou JQ; Shao WY; Peng D; Sun N; Wang XD; Wu WB; Bu XZ; Huang ZS; Ma DL; Wong KY; Gu LQ
    J Med Chem; 2008 Oct; 51(20):6381-92. PubMed ID: 18821749
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase.
    Zhou JL; Lu YJ; Ou TM; Zhou JM; Huang ZS; Zhu XF; Du CJ; Bu XZ; Ma L; Gu LQ; Li YM; Chan AS
    J Med Chem; 2005 Nov; 48(23):7315-21. PubMed ID: 16279791
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Detection of telomerase inhibitors based on g-quadruplex ligands by a modified telomeric repeat amplification protocol assay.
    Gomez D; Mergny JL; Riou JF
    Cancer Res; 2002 Jun; 62(12):3365-8. PubMed ID: 12067975
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Symmetrical bisbenzimidazoles with benzenediyl spacer: the role of the shape of the ligand on the stabilization and structural alterations in telomeric G-quadruplex DNA and telomerase inhibition.
    Bhattacharya S; Chaudhuri P; Jain AK; Paul A
    Bioconjug Chem; 2010 Jul; 21(7):1148-59. PubMed ID: 20536245
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Isaindigotone derivatives: a new class of highly selective ligands for telomeric G-quadruplex DNA.
    Tan JH; Ou TM; Hou JQ; Lu YJ; Huang SL; Luo HB; Wu JY; Huang ZS; Wong KY; Gu LQ
    J Med Chem; 2009 May; 52(9):2825-35. PubMed ID: 19354252
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure.
    Rezler EM; Seenisamy J; Bashyam S; Kim MY; White E; Wilson WD; Hurley LH
    J Am Chem Soc; 2005 Jul; 127(26):9439-47. PubMed ID: 15984871
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A new steroid derivative stabilizes g-quadruplexes and induces telomere uncapping in human tumor cells.
    Brassart B; Gomez D; De Cian A; Paterski R; Montagnac A; Qui KH; Temime-Smaali N; Trentesaux C; Mergny JL; Gueritte F; Riou JF
    Mol Pharmacol; 2007 Sep; 72(3):631-40. PubMed ID: 17586599
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [G-quadruplex DNA: myth or reality?].
    Riou JF; Gomez D; Lemarteleur T; Trentesaux C
    Bull Cancer; 2003 Apr; 90(4):305-13. PubMed ID: 12801813
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Disubstituted 2-phenyl-benzopyranopyrimidine derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA.
    Wu WB; Chen SH; Hou JQ; Tan JH; Ou TM; Huang SL; Li D; Gu LQ; Huang ZS
    Org Biomol Chem; 2011 Apr; 9(8):2975-86. PubMed ID: 21373680
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting telomerase and telomeres: a click chemistry approach towards highly selective G-quadruplex ligands.
    Moorhouse AD; Haider S; Gunaratnam M; Munnur D; Neidle S; Moses JE
    Mol Biosyst; 2008 Jun; 4(6):629-42. PubMed ID: 18493662
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of novel 4,5-bis(dialkylaminoalkyl)-substituted acridines as potent telomeric G-quadruplex ligands.
    Laronze-Cochard M; Kim YM; Brassart B; Riou JF; Laronze JY; Sapi J
    Eur J Med Chem; 2009 Oct; 44(10):3880-8. PubMed ID: 19467742
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Remarkable interference with telomeric function by a G-quadruplex selective bisantrene regioisomer.
    Folini M; Pivetta C; Zagotto G; De Marco C; Palumbo M; Zaffaroni N; Sissi C
    Biochem Pharmacol; 2010 Jun; 79(12):1781-90. PubMed ID: 20206144
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Trisubstituted acridines as G-quadruplex telomere targeting agents. Effects of extensions of the 3,6- and 9-side chains on quadruplex binding, telomerase activity, and cell proliferation.
    Moore MJ; Schultes CM; Cuesta J; Cuenca F; Gunaratnam M; Tanious FA; Wilson WD; Neidle S
    J Med Chem; 2006 Jan; 49(2):582-99. PubMed ID: 16420044
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Promoting the formation and stabilization of human telomeric G-quadruplex DNA, inhibition of telomerase and cytotoxicity by phenanthroline derivatives.
    Wang L; Wen Y; Liu J; Zhou J; Li C; Wei C
    Org Biomol Chem; 2011 Apr; 9(8):2648-53. PubMed ID: 21347502
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Disubstituted quinazoline derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA.
    Li Z; Tan JH; He JH; Long Y; Ou TM; Li D; Gu LQ; Huang ZS
    Eur J Med Chem; 2012 Jan; 47(1):299-311. PubMed ID: 22104971
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NMR-Based model of a telomerase-inhibiting compound bound to G-quadruplex DNA.
    Fedoroff OY; Salazar M; Han H; Chemeris VV; Kerwin SM; Hurley LH
    Biochemistry; 1998 Sep; 37(36):12367-74. PubMed ID: 9730808
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural basis for telomeric G-quadruplex targeting by naphthalene diimide ligands.
    Collie GW; Promontorio R; Hampel SM; Micco M; Neidle S; Parkinson GN
    J Am Chem Soc; 2012 Feb; 134(5):2723-31. PubMed ID: 22280460
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.