These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

97 related articles for article (PubMed ID: 17575232)

  • 1. Proteomic analysis identifies oxidative stress induction by adaphostin.
    Stockwin LH; Bumke MA; Yu SX; Webb SP; Collins JR; Hollingshead MG; Newton DL
    Clin Cancer Res; 2007 Jun; 13(12):3667-81. PubMed ID: 17575232
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transcriptional profiling identifies altered intracellular labile iron homeostasis as a contributing factor to the toxicity of adaphostin: decreased vascular endothelial growth factor secretion is independent of hypoxia-inducible factor-1 regulation.
    Hose C; Kaur G; Sausville EA; Monks A
    Clin Cancer Res; 2005 Sep; 11(17):6370-81. PubMed ID: 16144942
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Adaphostin cytoxicity in glioblastoma cells is ROS-dependent and is accompanied by upregulation of heme oxygenase-1.
    Long J; Manchandia T; Ban K; Gao S; Miller C; Chandra J
    Cancer Chemother Pharmacol; 2007 Mar; 59(4):527-35. PubMed ID: 16924499
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Combinatorial effects of histone deacetylase inhibitors (HDACi), vorinostat and entinostat, and adaphostin are characterized by distinct redox alterations.
    Rivera-Del Valle N; Cheng T; Irwin ME; Donnella H; Singh MM; Chandra J
    Cancer Chemother Pharmacol; 2018 Mar; 81(3):483-495. PubMed ID: 29313067
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Preclinical pharmacology of the novel antitumor agent adaphostin, a tyrphostin analog that inhibits bcr/abl.
    Li M; Wang H; Hill DL; Stinson S; Veley K; Grossi I; Peggins J; Covey JM; Zhang R
    Cancer Chemother Pharmacol; 2006 May; 57(5):607-14. PubMed ID: 16331493
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Adaphostin and bortezomib induce oxidative injury and apoptosis in imatinib mesylate-resistant hematopoietic cells expressing mutant forms of Bcr/Abl.
    Dasmahapatra G; Nguyen TK; Dent P; Grant S
    Leuk Res; 2006 Oct; 30(10):1263-72. PubMed ID: 16481037
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1.
    Fer ND; Shoemaker RH; Monks A
    J Exp Clin Cancer Res; 2010 Jul; 29(1):91. PubMed ID: 20618971
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modulation of arsenic trioxide-induced apoptosis by genistein and functionally related agents in U937 human leukaemia cells. Regulation by ROS and mitogen-activated protein kinases.
    Sánchez Y; Calle C; de Blas E; Aller P
    Chem Biol Interact; 2009 Nov; 182(1):37-44. PubMed ID: 19720055
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Involvement of reactive oxygen species in adaphostin-induced cytotoxicity in human leukemia cells.
    Chandra J; Hackbarth J; Le S; Loegering D; Bone N; Bruzek LM; Narayanan VL; Adjei AA; Kay NE; Tefferi A; Karp JE; Sausville EA; Kaufmann SH
    Blood; 2003 Dec; 102(13):4512-9. PubMed ID: 12920036
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of mitochondrial respiration as a source of adaphostin-induced reactive oxygen species and cytotoxicity.
    Le SB; Hailer MK; Buhrow S; Wang Q; Flatten K; Pediaditakis P; Bible KC; Lewis LD; Sausville EA; Pang YP; Ames MM; Lemasters JJ; Holmuhamedov EL; Kaufmann SH
    J Biol Chem; 2007 Mar; 282(12):8860-72. PubMed ID: 17213201
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Adaphostin-induced apoptosis in CLL B cells is associated with induction of oxidative stress and exhibits synergy with fludarabine.
    Shanafelt TD; Lee YK; Bone ND; Strege AK; Narayanan VL; Sausville EA; Geyer SM; Kaufmann SH; Kay NE
    Blood; 2005 Mar; 105(5):2099-106. PubMed ID: 15388586
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ICAT as a potential enhancer of monocytic differentiation: implications from the comparative proteome analysis of the HL60 cell line stimulated by all-trans retinoic acid and NSC67657.
    Wang W; Zhang X; Deng K; Huang S; Mao X; Fu Y; Yi Z; Yan Y; Qiu Z
    Cell Biochem Funct; 2009 Aug; 27(6):329-37. PubMed ID: 19569129
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The tyrphostin adaphostin interacts synergistically with proteasome inhibitors to induce apoptosis in human leukemia cells through a reactive oxygen species (ROS)-dependent mechanism.
    Dasmahapatra G; Rahmani M; Dent P; Grant S
    Blood; 2006 Jan; 107(1):232-40. PubMed ID: 16166589
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proteomic profiling of human retinal and choroidal endothelial cells reveals molecular heterogeneity related to tissue of origin.
    Zamora DO; Riviere M; Choi D; Pan Y; Planck SR; Rosenbaum JT; David LL; Smith JR
    Mol Vis; 2007 Oct; 13():2058-65. PubMed ID: 18079679
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Proteomic analysis of liver cancer cells treated with suberonylanilide hydroxamic acid.
    Tong A; Zhang H; Li Z; Gou L; Wang Z; Wei H; Tang M; Liang S; Chen L; Huang C; Wei Y
    Cancer Chemother Pharmacol; 2008 Apr; 61(5):791-802. PubMed ID: 17593366
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Proteomic analysis of an imatinib-resistant K562 cell line highlights opposing roles of heat shock cognate 70 and heat shock 70 proteins in resistance.
    Pocaly M; Lagarde V; Etienne G; Dupouy M; Lapaillerie D; Claverol S; Vilain S; Bonneu M; Turcq B; Mahon FX; Pasquet JM
    Proteomics; 2008 Jun; 8(12):2394-406. PubMed ID: 18563733
    [TBL] [Abstract][Full Text] [Related]  

  • 17. D-Serine exposure resulted in gene expression changes indicative of activation of fibrogenic pathways and down-regulation of energy metabolism and oxidative stress response.
    Soto A; DelRaso NJ; Schlager JJ; Chan VT
    Toxicology; 2008 Jan; 243(1-2):177-92. PubMed ID: 18061331
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Proteomic profiling of proteins associated with methamphetamine-induced neurotoxicity in different regions of rat brain.
    Li X; Wang H; Qiu P; Luo H
    Neurochem Int; 2008 Jan; 52(1-2):256-64. PubMed ID: 17904249
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparative proteome profiling and functional analysis of chronic myelogenous leukemia cell lines.
    Fontana S; Alessandro R; Barranca M; Giordano M; Corrado C; Zanella-Cleon I; Becchi M; Kohn EC; De Leo G
    J Proteome Res; 2007 Nov; 6(11):4330-42. PubMed ID: 17935311
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of platensic alcohol as an adamantane surrogate in antitumor drug lead adaphostin.
    Wen Z; Duan Y; Xiong Y; Huang Y
    Bioorg Med Chem Lett; 2021 Sep; 48():128270. PubMed ID: 34284106
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.