155 related articles for article (PubMed ID: 17575588)
1. Troglitazone hepatotoxicity: are we getting closer to understanding idiosyncratic liver injury?
Jaeschke H
Toxicol Sci; 2007 May; 97(1):1-3. PubMed ID: 17575588
[No Abstract] [Full Text] [Related]
2. Troglitazone-induced hepatic necrosis in an animal model of silent genetic mitochondrial abnormalities.
Ong MM; Latchoumycandane C; Boelsterli UA
Toxicol Sci; 2007 May; 97(1):205-13. PubMed ID: 17150972
[TBL] [Abstract][Full Text] [Related]
3. The mitochondrial superoxide/thioredoxin-2/Ask1 signaling pathway is critically involved in troglitazone-induced cell injury to human hepatocytes.
Lim PL; Liu J; Go ML; Boelsterli UA
Toxicol Sci; 2008 Feb; 101(2):341-9. PubMed ID: 17975114
[TBL] [Abstract][Full Text] [Related]
4. Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2(+/-) mice: two-stage oxidative injury.
Lee YH; Chung MC; Lin Q; Boelsterli UA
Toxicol Appl Pharmacol; 2008 Aug; 231(1):43-51. PubMed ID: 18495193
[TBL] [Abstract][Full Text] [Related]
5. Integrative toxicoproteomics implicates impaired mitochondrial glutathione import as an off-target effect of troglitazone.
Lee YH; Goh WW; Ng CK; Raida M; Wong L; Lin Q; Boelsterli UA; Chung MC
J Proteome Res; 2013 Jun; 12(6):2933-45. PubMed ID: 23659346
[TBL] [Abstract][Full Text] [Related]
6. Increased susceptibility to troglitazone-induced mitochondrial permeability transition in type 2 diabetes mellitus model rat.
Segawa M; Sekine S; Sato T; Ito K
J Toxicol Sci; 2018; 43(5):339-351. PubMed ID: 29743445
[TBL] [Abstract][Full Text] [Related]
7. Mechanisms of troglitazone hepatotoxicity.
Smith MT
Chem Res Toxicol; 2003 Jun; 16(6):679-87. PubMed ID: 12807350
[No Abstract] [Full Text] [Related]
8. Mitochondrial permeability transition as a potential determinant of hepatotoxicity of antidiabetic thiazolidinediones.
Masubuchi Y; Kano S; Horie T
Toxicology; 2006 May; 222(3):233-9. PubMed ID: 16621215
[TBL] [Abstract][Full Text] [Related]
9. Usefulness of in vitro combination assays of mitochondrial dysfunction and apoptosis for the estimation of potential risk of idiosyncratic drug induced liver injury.
Goda K; Takahashi T; Kobayashi A; Shoda T; Kuno H; Sugai S
J Toxicol Sci; 2016; 41(5):605-15. PubMed ID: 27665770
[TBL] [Abstract][Full Text] [Related]
10. Agree that idiosyncratic hepatotoxicity in TRO-treated patients is uncertain, but concerned about the data.
Kostrubsky VE; Rahbari R; Lodola A; Davies T
Toxicol Sci; 2003 Feb; 71(2):282; author reply 282-4. PubMed ID: 12563115
[No Abstract] [Full Text] [Related]
11. Troglitazone induces cytotoxicity in part by promoting the degradation of peroxisome proliferator-activated receptor γ co-activator-1α protein.
Liao X; Wang Y; Wong CW
Br J Pharmacol; 2010 Oct; 161(4):771-81. PubMed ID: 20860658
[TBL] [Abstract][Full Text] [Related]
12. Multiple mechanisms underlying troglitazone-induced mitochondrial permeability transition.
Okuda T; Norioka M; Shitara Y; Horie T
Toxicol Appl Pharmacol; 2010 Nov; 248(3):242-8. PubMed ID: 20709092
[TBL] [Abstract][Full Text] [Related]
13. Characterizing the mechanism of thiazolidinedione-induced hepatotoxicity: An in vitro model in mitochondria.
Hu D; Wu CQ; Li ZJ; Liu Y; Fan X; Wang QJ; Ding RG
Toxicol Appl Pharmacol; 2015 Apr; 284(2):134-41. PubMed ID: 25727309
[TBL] [Abstract][Full Text] [Related]
14. Troglitazone.
Yokoi T
Handb Exp Pharmacol; 2010; (196):419-35. PubMed ID: 20020270
[TBL] [Abstract][Full Text] [Related]
15. Application of systems pharmacology to explore mechanisms of hepatotoxicity.
Shon J; Abernethy DR
Clin Pharmacol Ther; 2014 Nov; 96(5):536-7. PubMed ID: 25336266
[TBL] [Abstract][Full Text] [Related]
16. Involvement of organic anion transporting polypeptides in the transport of troglitazone sulfate: implications for understanding troglitazone hepatotoxicity.
Nozawa T; Sugiura S; Nakajima M; Goto A; Yokoi T; Nezu J; Tsuji A; Tamai I
Drug Metab Dispos; 2004 Mar; 32(3):291-4. PubMed ID: 14977862
[TBL] [Abstract][Full Text] [Related]
17. Sensitivity of liver injury in heterozygous Sod2 knockout mice treated with troglitazone or acetaminophen.
Fujimoto K; Kumagai K; Ito K; Arakawa S; Ando Y; Oda S; Yamoto T; Manabe S
Toxicol Pathol; 2009 Feb; 37(2):193-200. PubMed ID: 19332662
[TBL] [Abstract][Full Text] [Related]
18. Real-time concurrent monitoring of apoptosis, cytosolic calcium, and mitochondria permeability transition for hypermulticolor high-content screening of drug-induced mitochondrial dysfunction-mediated hepatotoxicity.
Kim JA; Han E; Eun CJ; Tak YK; Song JM
Toxicol Lett; 2012 Oct; 214(2):175-81. PubMed ID: 22981620
[TBL] [Abstract][Full Text] [Related]
19. Systems pharmacology modeling predicts delayed presentation and species differences in bile acid-mediated troglitazone hepatotoxicity.
Yang K; Woodhead JL; Watkins PB; Howell BA; Brouwer KL
Clin Pharmacol Ther; 2014 Nov; 96(5):589-98. PubMed ID: 25068506
[TBL] [Abstract][Full Text] [Related]
20. Mitochondrial dysfunction and delayed hepatotoxicity: another lesson from troglitazone.
Julie NL; Julie IM; Kende AI; Wilson GL
Diabetologia; 2008 Nov; 51(11):2108-16. PubMed ID: 18726085
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]