385 related articles for article (PubMed ID: 17576805)
1. Characterization of diuron N-demethylation by mammalian hepatic microsomes and cDNA-expressed human cytochrome P450 enzymes.
Abass K; Reponen P; Turpeinen M; Jalonen J; Pelkonen O
Drug Metab Dispos; 2007 Sep; 35(9):1634-41. PubMed ID: 17576805
[TBL] [Abstract][Full Text] [Related]
2. Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: molecular base for interaction potential and variable disposition of active metabolites.
Botsch S; Gautier JC; Beaune P; Eichelbaum M; Kroemer HK
Mol Pharmacol; 1993 Jan; 43(1):120-6. PubMed ID: 8423765
[TBL] [Abstract][Full Text] [Related]
3. Biotransformation of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes.
Yao HT; Wu YS; Chang YW; Hsieh HP; Chen WC; Lan SJ; Chen CT; Chao YS; Chang L; Sun HY; Yeh TK
Drug Metab Dispos; 2007 Jul; 35(7):1042-9. PubMed ID: 17403915
[TBL] [Abstract][Full Text] [Related]
4. Species differences in the toxicity and cytochrome P450 IIIA-dependent metabolism of digitoxin.
Eberhart DC; Gemzik B; Halvorson MR; Parkinson A
Mol Pharmacol; 1991 Nov; 40(5):859-67. PubMed ID: 1944247
[TBL] [Abstract][Full Text] [Related]
5. Identification of human cytochrome p450 isozymes involved in diphenhydramine N-demethylation.
Akutsu T; Kobayashi K; Sakurada K; Ikegaya H; Furihata T; Chiba K
Drug Metab Dispos; 2007 Jan; 35(1):72-8. PubMed ID: 17020955
[TBL] [Abstract][Full Text] [Related]
6. In vitro characterization of the metabolism of haloperidol using recombinant cytochrome p450 enzymes and human liver microsomes.
Fang J; McKay G; Song J; Remillrd A; Li X; Midha K
Drug Metab Dispos; 2001 Dec; 29(12):1638-43. PubMed ID: 11717183
[TBL] [Abstract][Full Text] [Related]
7. Preclinical pharmacokinetics and metabolism of 6-(4-(2,5-difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a]pyridine, a novel and selective p38alpha inhibitor: identification of an active metabolite in preclinical species and human liver microsomes.
Kalgutkar AS; Hatch HL; Kosea F; Nguyen HT; Choo EF; McClure KF; Taylor TJ; Henne KR; Kuperman AV; Dombroski MA; Letavic MA
Biopharm Drug Dispos; 2006 Nov; 27(8):371-86. PubMed ID: 16944451
[TBL] [Abstract][Full Text] [Related]
8. Metabolism of dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate (DDB) by human liver microsomes: characterization of metabolic pathways and of cytochrome P450 isoforms involved.
Baek MS; Kim JY; Myung SW; Yim YH; Jeong JH; Kim DH
Drug Metab Dispos; 2001 Apr; 29(4 Pt 1):381-8. PubMed ID: 11259320
[TBL] [Abstract][Full Text] [Related]
9. Specificity of cDNA-expressed human and rodent cytochrome P450s in the oxidative metabolism of the potent carcinogen 7,12-dimethylbenz[a]anthracene.
Shou M; Korzekwa KR; Krausz KW; Buters JT; Grogan J; Goldfarb I; Hardwick JP; Gonzalez FJ; Gelboin HV
Mol Carcinog; 1996 Dec; 17(4):241-9. PubMed ID: 8989918
[TBL] [Abstract][Full Text] [Related]
10. Studies on the metabolism of the novel, selective cyclooxygenase-2 inhibitor indomethacin phenethylamide in rat, mouse, and human liver microsomes: identification of active metabolites.
Remmel RP; Crews BC; Kozak KR; Kalgutkar AS; Marnett LJ
Drug Metab Dispos; 2004 Jan; 32(1):113-22. PubMed ID: 14709628
[TBL] [Abstract][Full Text] [Related]
11. Comparative metabolism of cinobufagin in liver microsomes from mouse, rat, dog, minipig, monkey, and human.
Ma XC; Ning J; Ge GB; Liang SC; Wang XL; Zhang BJ; Huang SS; Li JK; Yang L
Drug Metab Dispos; 2011 Apr; 39(4):675-82. PubMed ID: 21205911
[TBL] [Abstract][Full Text] [Related]
12. The involvement of cytochrome P450 3A4 in the N-demethylation of L-alpha-acetylmethadol (LAAM), norLAAM, and methadone.
Moody DE; Alburges ME; Parker RJ; Collins JM; Strong JM
Drug Metab Dispos; 1997 Dec; 25(12):1347-53. PubMed ID: 9394023
[TBL] [Abstract][Full Text] [Related]
13. Characterization of the cytochrome P450 enzymes involved in the metabolism of a new cardioprotective agent KR-33028.
Kim H; Yoon YJ; Kim H; Kang S; Cheon HG; Yoo SE; Shin JG; Liu KH
Toxicol Lett; 2006 Oct; 166(2):105-14. PubMed ID: 16857327
[TBL] [Abstract][Full Text] [Related]
14. Catalyzation of cocaine N-demethylation by cytochromes P4502B, P4503A, and P4502D in fish liver.
Arinç E; Bozcaarmutlu A
J Biochem Mol Toxicol; 2003; 17(3):169-76. PubMed ID: 12815613
[TBL] [Abstract][Full Text] [Related]
15. Characterization of triptolide hydroxylation by cytochrome P450 in human and rat liver microsomes.
Li W; Liu Y; He YQ; Zhang JW; Gao Y; Ge GB; Liu HX; Huo H; Liu HT; Wang LM; Sun J; Wang Q; Yang L
Xenobiotica; 2008 Dec; 38(12):1551-65. PubMed ID: 18982531
[TBL] [Abstract][Full Text] [Related]
16. Metabolism of 2-amino-alpha-carboline. A food-borne heterocyclic amine mutagen and carcinogen by human and rodent liver microsomes and by human cytochrome P4501A2.
Raza H; King RS; Squires RB; Guengerich FP; Miller DW; Freeman JP; Lang NP; Kadlubar FF
Drug Metab Dispos; 1996 Apr; 24(4):395-400. PubMed ID: 8801053
[TBL] [Abstract][Full Text] [Related]
17. Characterization of human liver cytochrome P450 enzymes involved in the metabolism of a new H+/K+-ATPase inhibitor KR-60436.
Ji HY; Lee HW; Kim HH; Choi JK; Lee HS
Toxicol Lett; 2005 Jan; 155(1):103-14. PubMed ID: 15585365
[TBL] [Abstract][Full Text] [Related]
18. 3-ketocholanoic acid is the major in vitro human hepatic microsomal metabolite of lithocholic acid.
Deo AK; Bandiera SM
Drug Metab Dispos; 2009 Sep; 37(9):1938-47. PubMed ID: 19487251
[TBL] [Abstract][Full Text] [Related]
19. In vitro identification of the human cytochrome P-450 enzymes involved in the N-demethylation of azelastine.
Imai T; Taketani M; Suzu T; Kusube K; Otagiri M
Drug Metab Dispos; 1999 Aug; 27(8):942-6. PubMed ID: 10421623
[TBL] [Abstract][Full Text] [Related]
20. Contribution of individual cytochrome P450 isozymes to the O-demethylation of the psychotropic beta-carboline alkaloids harmaline and harmine.
Yu AM; Idle JR; Krausz KW; Küpfer A; Gonzalez FJ
J Pharmacol Exp Ther; 2003 Apr; 305(1):315-22. PubMed ID: 12649384
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
