102 related articles for article (PubMed ID: 17583504)
1. Pyrrolidino-tetrahydroisoquinolines bearing pendant heterocycles as potent dual H3 antagonist and serotonin transporter inhibitors.
Keith JM; Gomez LA; Barbier AJ; Wilson SJ; Boggs JD; Lord B; Mazur C; Aluisio L; Lovenberg TW; Carruthers NI
Bioorg Med Chem Lett; 2007 Aug; 17(15):4374-7. PubMed ID: 17583504
[TBL] [Abstract][Full Text] [Related]
2. Dual serotonin transporter inhibitor/histamine H3 antagonists: development of rigidified H3 pharmacophores.
Keith JM; Barbier AJ; Wilson SJ; Miller K; Boggs JD; Fraser IC; Mazur C; Lovenberg TW; Carruthers NI
Bioorg Med Chem Lett; 2007 Oct; 17(19):5325-9. PubMed ID: 17765543
[TBL] [Abstract][Full Text] [Related]
3. Dual serotonin transporter/histamine H3 ligands: Optimization of the H3 pharmacophore.
Keith JM; Gomez LA; Letavic MA; Ly KS; Jablonowski JA; Seierstad M; Barbier AJ; Wilson SJ; Boggs JD; Fraser IC; Mazur C; Lovenberg TW; Carruthers NI
Bioorg Med Chem Lett; 2007 Feb; 17(3):702-6. PubMed ID: 17107798
[TBL] [Abstract][Full Text] [Related]
4. Structure-activity relationships of arylbenzofuran H3 receptor antagonists.
Gfesser GA; Faghih R; Bennani YL; Curtis MP; Esbenshade TA; Hancock AA; Cowart MD
Bioorg Med Chem Lett; 2005 May; 15(10):2559-63. PubMed ID: 15863316
[TBL] [Abstract][Full Text] [Related]
5. Novel tetrahydroisoquinolines are histamine H3 antagonists and serotonin reuptake inhibitors.
Letavic MA; Keith JM; Jablonowski JA; Stocking EM; Gomez LA; Ly KS; Miller JM; Barbier AJ; Bonaventure P; Boggs JD; Wilson SJ; Miller KL; Lord B; McAllister HM; Tognarelli DJ; Wu J; Abad MC; Schubert C; Lovenberg TW; Carruthers NI
Bioorg Med Chem Lett; 2007 Feb; 17(4):1047-51. PubMed ID: 17127059
[TBL] [Abstract][Full Text] [Related]
6. Pyrrolidino-tetrahydroisoquinolines as potent dual H3 antagonist and serotonin transporter inhibitors.
Keith JM; Gomez LA; Wolin RL; Barbier AJ; Wilson SJ; Boggs JD; Mazur C; Fraser IC; Lord B; Aluisio L; Lovenberg TW; Carruthers NI
Bioorg Med Chem Lett; 2007 May; 17(9):2603-7. PubMed ID: 17317177
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and SAR of novel histamine H3 receptor antagonists.
Jesudason CD; Beavers LS; Cramer JW; Dill J; Finley DR; Lindsley CW; Stevens FC; Gadski RA; Oldham SW; Pickard RT; Siedem CS; Sindelar DK; Singh A; Watson BM; Hipskind PA
Bioorg Med Chem Lett; 2006 Jul; 16(13):3415-8. PubMed ID: 16677814
[TBL] [Abstract][Full Text] [Related]
8. Stereochemical diversity-oriented conformational restriction strategy. Development of potent histamine H3 and/or H4 receptor antagonists with an imidazolylcyclopropane structure.
Watanabe M; Kazuta Y; Hayashi H; Yamada S; Matsuda A; Shuto S
J Med Chem; 2006 Sep; 49(18):5587-96. PubMed ID: 16942032
[TBL] [Abstract][Full Text] [Related]
9. 2-(4-alkylpiperazin-1-yl)quinolines as a new class of imidazole-free histamine H3 receptor antagonists.
Zaragoza F; Stephensen H; Peschke B; Rimvall K
J Med Chem; 2005 Jan; 48(1):306-11. PubMed ID: 15634025
[TBL] [Abstract][Full Text] [Related]
10. Novel substituted pyrrolidines are high affinity histamine H3 receptor antagonists.
Stocking EM; Aluisio L; Atack JR; Bonaventure P; Carruthers NI; Dugovic C; Everson A; Fraser I; Jiang X; Leung P; Lord B; Ly KS; Morton KL; Nepomuceno D; Shah CR; Shelton J; Soyode-Johnson A; Letavic MA
Bioorg Med Chem Lett; 2010 May; 20(9):2755-60. PubMed ID: 20382018
[TBL] [Abstract][Full Text] [Related]
11. Application of the statistical methods in systematic structure-activity relationship analysis of thiazole, benzothiazole and tetrahydroisoquinoline derivatives with biological activity.
Brzezińska EO; Stolarska JD
Acta Pol Pharm; 2009; 66(1):25-35. PubMed ID: 19226965
[TBL] [Abstract][Full Text] [Related]
12. A new family of H3 receptor antagonists based on the natural product Conessine.
Santora VJ; Covel JA; Hayashi R; Hofilena BJ; Ibarra JB; Pulley MD; Weinhouse MI; Sengupta D; Duffield JJ; Semple G; Webb RR; Sage C; Ren A; Pereira G; Knudsen J; Edwards JE; Suarez M; Frazer J; Thomsen W; Hauser E; Whelan K; Grottick AJ
Bioorg Med Chem Lett; 2008 Feb; 18(4):1490-4. PubMed ID: 18194865
[TBL] [Abstract][Full Text] [Related]
13. Pharmacological characterization of JNJ-28583867, a histamine H(3) receptor antagonist and serotonin reuptake inhibitor.
Barbier AJ; Aluisio L; Lord B; Qu Y; Wilson SJ; Boggs JD; Bonaventure P; Miller K; Fraser I; Dvorak L; Pudiak C; Dugovic C; Shelton J; Mazur C; Letavic MA; Carruthers NI; Lovenberg TW
Eur J Pharmacol; 2007 Dec; 576(1-3):43-54. PubMed ID: 17765221
[TBL] [Abstract][Full Text] [Related]
14. The synthesis of substituted fluorenes as novel non-imidazole histamine h(3) inhibitors.
Ting P; Lee J; Albanese M; Tom W; Solomon D; Aslanian R; Shih N; West R
Bioorg Med Chem Lett; 2002 Sep; 12(18):2643-6. PubMed ID: 12182878
[TBL] [Abstract][Full Text] [Related]
15. Trans-4-methyl-3-imidazoyl pyrrolidine as a potent, highly selective histamine H3 receptor agonist in vivo.
Shih NY; Aslanian R; Lupo AT; Orlando S; Piwinski JJ; Green MJ; Ganguly AK; West R; Tozzi S; Kreutner W; Hey JA
Bioorg Med Chem Lett; 1998 Feb; 8(3):243-8. PubMed ID: 9871662
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and structure-activity relationships of novel histamine H1 antagonists: indolylpiperidinyl benzoic acid derivatives.
Fonquerna S; Miralpeix M; Pagès L; Puig C; Cardús A; Antón F; Cárdenas A; Vilella D; Aparici M; Calaf E; Prieto J; Gras J; Huerta JM; Warrellow G; Beleta J; Ryder H
J Med Chem; 2004 Dec; 47(25):6326-37. PubMed ID: 15566302
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of novel gamma-carboline analogues of Dimebon as potent 5-HT6 receptor antagonists.
Ivachtchenko AV; Frolov EB; Mitkin OD; Kysil VM; Khvat AV; Okun IM; Tkachenko SE
Bioorg Med Chem Lett; 2009 Jun; 19(12):3183-7. PubMed ID: 19443217
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and structure-activity relationships for biphenyl H3 receptor antagonists with moderate anti-cholinesterase activity.
Morini G; Comini M; Rivara M; Rivara S; Bordi F; Plazzi PV; Flammini L; Saccani F; Bertoni S; Ballabeni V; Barocelli E; Mor M
Bioorg Med Chem; 2008 Dec; 16(23):9911-24. PubMed ID: 18976927
[TBL] [Abstract][Full Text] [Related]
19. Antiobesity evaluation of histamine H3 receptor (H3R) antagonist analogs of A-331440 with improved safety and efficacy.
Hancock AA; Diehl MS; Fey TA; Bush EN; Faghih R; Miller TR; Krueger KM; Pratt JK; Cowart MD; Dickinson RW; Shapiro R; Knourek-Segel VE; Droz BA; McDowell CA; Krishna G; Brune ME; Esbenshade TA; Jacobson PB
Inflamm Res; 2005 Apr; 54 Suppl 1():S27-9. PubMed ID: 15928821
[No Abstract] [Full Text] [Related]
20. Non-imidazole histamine H3 ligands, part IV: SAR of 1-[2-thiazol-5-yl-(2-aminoethyl)]-4-n-propylpiperazine derivatives.
Frymarkiewicz A; Walczyński K
Eur J Med Chem; 2009 Apr; 44(4):1674-81. PubMed ID: 18990469
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]