BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 17585201)

  • 1. p21 (CDKN1A) is a negative regulator of p53 stability.
    Broude EV; Demidenko ZN; Vivo C; Swift ME; Davis BM; Blagosklonny MV; Roninson IB
    Cell Cycle; 2007 Jun; 6(12):1468-71. PubMed ID: 17585201
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mdm2 is required for inhibition of Cdk2 activity by p21, thereby contributing to p53-dependent cell cycle arrest.
    Giono LE; Manfredi JJ
    Mol Cell Biol; 2007 Jun; 27(11):4166-78. PubMed ID: 17371838
    [TBL] [Abstract][Full Text] [Related]  

  • 3. p21(Waf1/Cip1/Sdi1) mediates retinoblastoma protein degradation.
    Broude EV; Swift ME; Vivo C; Chang BD; Davis BM; Kalurupalle S; Blagosklonny MV; Roninson IB
    Oncogene; 2007 Oct; 26(48):6954-8. PubMed ID: 17486059
    [TBL] [Abstract][Full Text] [Related]  

  • 4. c-ABL tyrosine kinase modulates p53-dependent p21 induction and ensuing cell fate decision in response to DNA damage.
    Udden SM; Morita-Fujimura Y; Satake M; Ikawa S
    Cell Signal; 2014 Feb; 26(2):444-52. PubMed ID: 24177958
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypersensitivity to chromium-induced DNA damage correlates with constitutive deregulation of upstream p53 kinases in p21-/- HCT116 colon cancer cells.
    Hill R; Leidal AM; Madureira PA; Gillis LD; Cochrane HK; Waisman DM; Chiu A; Lee PW
    DNA Repair (Amst); 2008 Feb; 7(2):239-52. PubMed ID: 18024214
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ras association domain family 1 isoform A suppresses colonic tumor cell growth through p21
    Oh SJ; Lee MG; Moon JR; Lee CK; Chi SG; Kim HJ
    J Gastroenterol Hepatol; 2019 May; 34(5):890-898. PubMed ID: 30226276
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p21
    Lee J; Kim J; Kim EM; Kim U; Kang AR; Park JK; Um HD
    Biochem Biophys Res Commun; 2021 Mar; 543():23-28. PubMed ID: 33503543
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stabilization of P/CAF, as a ubiquitin ligase toward MDM2, suppresses mitotic cell death through p53-p21 activation in HCT116 cells with SIRT2 suppression.
    Li Y; Kokura K; Inoue T
    Biochem Biophys Res Commun; 2019 Jan; 508(1):230-236. PubMed ID: 30482390
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Influence of zinc deficiency on Akt-Mdm2-p53 and Akt-p21 signaling axes in normal and malignant human prostate cells.
    Han CT; Schoene NW; Lei KY
    Am J Physiol Cell Physiol; 2009 Nov; 297(5):C1188-99. PubMed ID: 19657064
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential regulation of p21 (waf1) protein half-life by DNA damage and Nutlin-3 in p53 wild-type tumors and its therapeutic implications.
    Chang LJ; Eastman A
    Cancer Biol Ther; 2012 Sep; 13(11):1047-57. PubMed ID: 22825333
    [TBL] [Abstract][Full Text] [Related]  

  • 11. hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage.
    Moumen A; Masterson P; O'Connor MJ; Jackson SP
    Cell; 2005 Dec; 123(6):1065-78. PubMed ID: 16360036
    [TBL] [Abstract][Full Text] [Related]  

  • 12. p53-mediated control of gene expression via mRNA translation during Endoplasmic Reticulum stress.
    López I; Tournillon AS; Nylander K; Fåhraeus R
    Cell Cycle; 2015; 14(21):3373-8. PubMed ID: 26397130
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.
    Choi HJ; Chung TW; Kang SK; Lee YC; Ko JH; Kim JG; Kim CH
    Glycobiology; 2006 Jul; 16(7):573-83. PubMed ID: 16574813
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The kinetics of p53-binding and histone acetylation at target promoters do not strictly correlate with gene expression after UV damage.
    Magrini R; Russo D; Fronza G; Inga A; Menichini P
    J Cell Biochem; 2007 Apr; 100(5):1276-87. PubMed ID: 17063487
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells.
    Brew CT; Aronchik I; Hsu JC; Sheen JH; Dickson RB; Bjeldanes LF; Firestone GL
    Int J Cancer; 2006 Feb; 118(4):857-68. PubMed ID: 16152627
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hsp90 inhibition has opposing effects on wild-type and mutant p53 and induces p21 expression and cytotoxicity irrespective of p53/ATM status in chronic lymphocytic leukaemia cells.
    Lin K; Rockliffe N; Johnson GG; Sherrington PD; Pettitt AR
    Oncogene; 2008 Apr; 27(17):2445-55. PubMed ID: 17982489
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mdm2 inhibition of p53 induces E2F1 transactivation via p21.
    Wunderlich M; Berberich SJ
    Oncogene; 2002 Jun; 21(28):4414-21. PubMed ID: 12080472
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential targeting of the cyclin-dependent kinase inhibitor, p21CIP1/WAF1, by chelators with anti-proliferative activity in a range of tumor cell-types.
    Moussa RS; Kovacevic Z; Richardson DR
    Oncotarget; 2015 Oct; 6(30):29694-711. PubMed ID: 26335183
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential response between the p53 ubiquitin-protein ligases Pirh2 and MdM2 following DNA damage in human cancer cells.
    Duan W; Gao L; Wu X; Zhang Y; Otterson GA; Villalona-Calero MA
    Exp Cell Res; 2006 Oct; 312(17):3370-8. PubMed ID: 16934800
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential regulation of the p21/WAF-1 and mdm2 genes after high-dose UV irradiation: p53-dependent and p53-independent regulation of the mdm2 gene.
    Wu L; Levine AJ
    Mol Med; 1997 Jul; 3(7):441-51. PubMed ID: 9260156
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.